Xin Jin on using genomic tools to understand brain development #singlecellgenomicsday Incredible resolution of brain architecture at multiple scales from the Perturb-CLEAR method
Thanks to our wonderful speakers, audience members, @ATJCagan, and @genome_gov (via @cegs_ica) for such an enjoyable #singlecellgenomicsday 2024! After 8 years of SCGD its incredible to see innovation in the field accelerating- see you next year!
TimeVault is one of the most exciting innovations highlighted at today’s Single‑Cell Genomics Day — a genetically encoded system enabling transcriptome “time‑storage” in mammalian cells.
The Nobel-winning trio uncovered a critical part of the immune system called regulatory T cells. Think of them as peacekeepers or referees. These cells help the immune system stay calm and avoid friendly fire.
👏 A huge congratulations to Brunkow, Ramsdell, and Sakaguchi for helping us better understand the delicate balance of immunity and tolerance. The immune system’s true sophistication lies in its ability to distinguish between threat and self—and to choose peace when needed.
🧬✨ Big news from the world of science: The 2025 Nobel Prize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi for their groundbreaking discoveries about how our immune system knows when not to attack.
In simple terms: our immune system is like a powerful security force. It’s trained to detect and destroy invaders like viruses and bacteria. But sometimes, it gets confused and starts attacking our own healthy cells. This is what happens in autoimmune diseases.
🏃♂️💓 Curious how intense exercise affects your heart’s right ventricle? Here’s what science says: Intense endurance exercise—like marathon running or long-distance cycling—can temporarily affect the right side of the heart, specifically the right ventricle.
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🧠 Why It Matters:Most heart research focuses on the left ventricle (the side that pumps blood to the body), but studies now show that the right ventricle also adapts—and sometimes struggles—under extreme physical stress.
📌 Bottom Line: Exercise is essential, but like anything, balance matters. It is important to understand how the heart adapts to physical demands—and why recovery and monitoring are key for those pushing their limits.