Trust your instincts.
I recently had my whole genome sequenced because of the number of cancers I have had over the years. The doctors at Stanford wanted to see if there was anything obvious going on.
My first melanoma was at age 33 on my shoulder. 7 since (arguing with the doctor's medical records vs my memory about whether it's 6 or 7), a whole bunch of basal cells, a squamous, and a renal cell kidney cancer (down to one kidney).
We got the genetics results a couple of weeks ago, and I am heterozygous MITF E318K
nature.com/articles/s41598-0… . It's a dominant autosomal cancer driver. Summary: puts me at risk for melanoma and kidney cancer-- so it all tracks with my history. Add in light skin, reddish hair, and Celtic heritage.
Given my family history, it is likely a mutation that occurred only in me, as no one else in the family has the same issues. The biology of MITF is fascinating. Being in the field of cancer research helps me understand how to mitigate risk.
So-- a public service announcement. Genetics drives a lot of cancer outcomes. If available-- get your genetics done and see your doctor if you have concerns. It does not go away if you ignore it.
The recent melanoma I had (biopsy last Wednesday, diagnosis today) was because I had a sense that a "spot" on my arm was wrong. All good, a bit of snip-snip and it will be taken care of. Another scar-- who cares? I've been at this for 30 years. I'll be perfectly fine... I get checked 3 to 4 times a year.
Trust your instincts with cancer. Save your own life. Be open to your friends who might have concerns. Help them feel comfortable getting themselves checked.
Cancer caught early can be cancer cured.