Fib-4 is the most widely accepted and used NIT (non-invasive test) for MASLD and MASH initial assessments. In this video fireside chat,
@wpbrouwer shares the recent study presented at
#easlcongress 2023: "METABOLIC DYSFUNCTION ASSOCIATED FIBROSIS-5 (MAF-5) SCORE ACCURATELY IDENTIFIES AT-RISK LIVER FIBROSIS AND PREDICTS PROGNOSIS IN A POPULATION-BASED SETTING".
From the
@EASLnews presentation:
"The MAF-5 is a validated, age-independent, inexpensive referral tool to identify patients at high risk of liver fibrosis in the primary care setting.
• It outperformed other NITs in the primary care setting especially in the younger and older populations and had a stable performance across (heterogeneous) populations
• It was significantly associated with biopsy-proven fibrosis severity in NAFLD/NASH patients
• MAF-5 was significantly associated with all-cause mortality
• The MAF-5 score may therefore be a good alternative for the FIB-4 for use in the referral pathway for liver-health evaluation."
Authors also include, Laurens van Kleef,
@FrancqueSven, Jhon E. Prieto-Ortiz, Milan J. Sonneveld, Carlos B. Sanchez-Luque, Robin G. Prieto-Ortiz, Wilhelmus J. Kwanten, Luisa Vonghia, An Verrijken, Christophe De Block, Zouhir Gadi, Harry Janssen, Robert J. de Knegt.