Synthetic organic chemistry group focused on the incorporation, homologation and functionalisation of organoboron compounds. Group ran account.
Joined September 2018
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151 Photos and videos
May 28
We would also like to say goodbye to Denisa, who is returning to the Czech Republic to finish her PhD. We hope you enjoyed your research visit in our group. All the best, Denisa! 🎉
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May 28
Today, we are *simultaneously* (pun intended; cf. JACS 2024, 146, 13719–13726) sad and delighted as Dr. Shen wraps up his time in our group. Sad to lose a postdoc powerhouse, but thrilled to see him kick off his independent career back in China. All the best, Hong Cheng! 🎉
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May 5
Avengers! Assemble... alkyl phosphonates.
Check out our new @angew_chem paper for the direct C(sp3)–H phosphonylation of unactivated alkanes ⚗️ Using an iron photocatalyst.
Congrats Team!
onlinelibrary.wiley.com/doi/…
@BristolChem #photocatalysis
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Apr 24
Our latest work with @duarte_group shows the unexpected exo-C2 lithiation of ABP and ABH, allowing access to ring-opening products with full stereocontrol.
Congrats Team!
#OrganicChemistry #StrainRelease @BristolChem
pubs.acs.org/doi/10.1021/jac…
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Apr 20
🎉 Chuffed to see our JACS paper is among the most read articles this month!
See how a boron-mediated Ni/photoredox strategy for hydroalkylation of olefins enabled the access to quaternary carbons.
pubs.acs.org/doi/10.1021/jac…
Congrats Team!
#Photoredox #Organoborons @BristolChem
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Apr 2
Mixed emotions… 😊 Proud that Dr. Liang Wei is starting his independent career at Huazhong University of Science and Technology 🇨🇳✨, but sad to say goodbye to one of the kindest and brightest postdocs in the Aggarwal Lab.
All the best, Liang! 🚀
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Mar 8
Au revoir, auf Wiedersehen, arrivederci! 👋
Time flies✈️,our three visiting researchers are now back to their home universities to continue their research journeys.
All the best to @GrossAdrien5 (🇫🇷 → Uni Freiburg 🇩🇪), Fin (Uni Hannover 🇩🇪), and Federica (Uni Pavia 🇮🇹)!
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Feb 25
Breaking the rule-of-five in [2 2] cycloadditions!⚡
Check out our @NatureSynthesis article where a radical stabilization strategy enabled Photo EnT route to elusive 3D-isosteres of 6 membered N-heterocycles.
nature.com/articles/s44160-0…
#Photocatalysis #bioisosteres @BristolChem
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Feb 2
The Bristol Synthesis Meeting is back!
📅 31 March 2026
Enjoy engaging and insightful chemistry talks from our esteemed guest speakers this spring.
The deadline for registration is 20th March 2026.
@LeonoriLab @BalskusLab @dixon_group @Huckgroup @BristolChem @DonnaBlackmond
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Feb 1
🎉 Huge congratulations to Hanwen on successfully defending his PhD thesis! He is now Dr. Zhang (张瀚文). Wishing you all the best to your future career!
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Jan 7
We skipped the year 2025, but Boron Ir skipped dienes!
Check out Liang and Zhouwen’s @J_A_C_S paper:
pubs.acs.org/doi/10.1021/jac…
...to see how to access skipped 1,4-dienes enantioselectivity. Congrats to the team! 🎉
@BristolChem #Organoborons
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15 Dec 2025
🌊🧪 Ready for the sequel of our marine polyketide study?
✅ Bioactivity & chemogenomic profiling
✅ Ultra-high-res. NMR
✅ Modular total synthesis
➡️ Caylobolide B unlocked!
doi.org/10.1002/anie.2025231…
Superb collaborative effort with the Luesch and Butts groups.
@BristolChem
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4 Dec 2025
Congratulations to Tom on successfully defending his thesis! He is now Dr. Plowright. Wishing him all the very best in his future career!
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4 Dec 2025
🚀Organoboron update!
Shubham, Tapas, and Hong-Cheng dive into 'Recent Advances in Stereospecific Transformations of Organoboron Reagents.'
Now out in the new open-access journal Transformative Chemistry. onlinelibrary.wiley.com/doi/…
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6 Oct 2025
⚛️ When Ir meets boranes, chemistry hits different!
Now in @J_A_C_S: Our Ir-catalyzed allylation via intermolecular 1,4-boronate rearrangement enables enantioselective access to (R)-pyricuol in 2 steps. 🎉 Congrats Team!
🔗 [pubs.acs.org/doi/10.1021/jac…]
@BristolChem @bobbypaton
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25 Aug 2025
🎉 Huge congratulations to Dr. Malcolm George on successfully defending his PhD thesis! He’s now joining Pharmaron as a Senior Scientist in Process Chemistry. Wishing him every success in this exciting new chapter! 👏
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5 Aug 2025
💍 Looking for a ring? try one with Bpins!
Check out our intramolecular lithiation–borylation route to 1,3-bis-boronic ester carbocycles, now out in @angew_chem.
Congrats Chris and team!
🔗onlinelibrary.wiley.com/doi/…
In collaboration with @merckgroup. #Organoborons @bristolchem
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28 Jul 2025
🌊 From a marine sponge to @angew_chem Novit!
Mycapolyol E: fully synthesized and structurally confirmed via boronic ester homologation.
20 steps (LLS). 12 stereocenters.
Congrats @sheenagh_aiken, @DylanRigby6 & team!
🔗 dx.doi.org/10.1002/anov.7000…
@BristolChem #TotalSynthesis
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3 Jul 2025
🌪️🔥🌊🌍 Mastering all four? We did it with alkenes!
Our @Nature paper with @bobbypaton lab reveals a modular boron-mediated strategy solving the long-standing challenge of accessing tetrasubstituted alkenes with full stereo-control. Congrats team!
nature.com/articles/s41586-0…
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