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Agostinis Lab @AgostinisLab

Laboratory of Cell Death Research and Therapy @vib_ccb @KU_Leuven

Joined April 2017
  • Tweets 232
  • Following 180
  • Followers 672
47 Photos and videos
doi.org/10.1038/s41556-025-0… 🚨 Where does #lipid peroxidation kick off in #ferroptosis?🔥Excited to reveal #ER-#mitochondria #contactsites as ignition point of the lipid peroxidation cascade! Huge kudos to our @SassanoLivia &our amazing collaborators making this breakthrough possible

Endoplasmic reticulum–mitochondria contacts are prime hotspots of phospholipid peroxidation driving...

Nature Cell Biology - Sassano et al. identify endoplasmic reticulum–mitochondria contact sites as the intracellular location where phospholipid peroxidation first occurs to promote...

nature.com
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It is time to leave! Together with a growing number of people and colleagues, we will no longer post or use our X account. You can find us here: @agostinislab.bsky.social. Hope to see you there soon!👋
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🥳 Happy to share our new preprint where we describe the molecular machinery regulating iron transport between lysosomes and mitochondria, how it controls the melanoma drug tolerant persister state and the consequences of its perturbation on ferroptosis 👉 researchsquare.com/article/r…
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Congrats @Franci_Rizz 👏🏻@Julie_bonnereau and all collaborators 🙏 and thanks to our funding agencies @FWOVlaanderen @Stkstichting @vib_ccb
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Absolutely! @CSHANews #Ferroptosis meeting was a huge success! We had a wonderful time in the beautiful Suzhou and discussed exciting science. Thanks to the organisers and to all participants for making this a memorable event! 👏👏👏
James Olzmann@OlzmannLab
8 Nov 2024
Had an amazing time at the @CSHANews #Ferroptosis meeting in Suzhou China! Amazing science and colleagues. Huge thank you to the organizers! 🤩
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🤩Thrilled to share our new study on the autocrine role of melanoma-secreted ApoE in controlling ferroptosis susceptibility across melanoma cell states👇@Sanket4578 et al. 1/3 science.org/doi/epdf/10.1126…

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We show that melanoma cell-derived ApoE reshapes lipid architecture and enhances the antioxidant system of the drug-tolerant melanoma cells shielding them from ferroptosis. 2/3
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Congratulations to our PhD student Sanket @Sanket4578 and a big thanks to all our collaborators @lab_marine @bstockwell @LambrechtsDlab Francesca Bosisio, Johannes Swimmen 🙏
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Agostinis Lab retweeted
The Conrad Lab@Conrad_Lab
11 Oct 2024
Thanks for your inspiring talk Francesca!
Francesca Rizzollo@Franci_Rizz
11 Oct 2024
Had a wonderful time at the 30th #ECDO24 in Luxembourg! Loved the inspiring talks of the pioneers of Ferroptosis @Conrad_Lab and @bstockwell and all the other incredibile scientists I had the honour to share the stage with 🤩
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Celebrating the 30th ECDO anniversary 🥳 at the ECDO meeting in Luxembourg with great colleagues @MMittelbrunn, @aksimonlab 🙌🏻 cell death-autophagy- immunology ! #ECDO2024 #celldeath
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Congrats to our Francesca Rizzollo, @Franci_Rizz for winning the 2024 Small World in Motion Competition | Nikon’s Small World:nikonsmallworld.com/gallerie…

Melanoma cells showing mitochondria and lysosome dynamics | 2024 Small World in Motion Competition

Nikky Corthout - Melanoma cells showing mitochondria and lysosome dynamics

nikonsmallworld.com
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It was a great pleasure to host Dr. Jessalyn Ubellacker (@HarvardChanSPH) at the CCB. Jessalyin gave a great talk on how melanoma cells metastasizing to the lymph node remodel their ferroptosis dependencies...and we had a wonderful time together in Leuven.
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Agostinis Lab retweeted
Brent Stockwell@bstockwell
4 Sep 2024
Looking forward to the CSHA #Ferroptosis #conference in Suzhou Nov 3-8! Abstract deadline has been extended to Sept 20th. Hope to see everyone there!
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Many congratulations to our postdoc @Julie_bonnereau for winning the @embojournal poster prize at #MRS2024 🥳👏🏻
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💡Another great talk of the last session of #ImmunoOnco24 from Johanna Olweus @JOIweus @UniOslo_Med on the identification of new T cell receptors and how they can be exploited to improve immunotherapy!!!
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Marta Lewandowska from @Mestagtx is giving an excellent talk at #ImmunoOnco24 on the interface of fibroblasts and immune cells interaction!
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🎯In the last session @CoukosGeorge @Ludwig_Cancer at #ImmunoOnco24 gave an enlightening talk on which T cells make it to the tumor in responder and non-responder cancer patients!
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How can we exploit T cells to improve immunotherapy in gliomas? Mind blowing talk from @platten_michael @Plattenlab on #ImmunoOnco24!!!
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Another great talk at #ImmunoOnco24 conference! Amanda Lund @theLundlab @nyulangone is explaining how we can target tumor-associated lymphangiogenesis to modulate metastasis!!!
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💡We just got a deep dive in the T cell dynamics in patients with triple negative breast cancer from Marleen Kok at #ImmunoOnco24 . Very interesting talk on the benefits of immunotherapy in TNBC!
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