Does a central PE automatically mean a higher-risk patient?
In this multicenter Annals of Emergency Medicine study of more than 1,700 ED patients with acute PE, central thrombus location was associated with advanced intervention use but not with in-hospital death, clinical deterioration, or 30-day mortality.
The findings suggest that RV dysfunction, tachycardia, and biomarker elevation may provide more clinically relevant information when assessing short-term risk.
Paper: Associations of the Composite Pulmonary
Embolism Shock Score in the Emergency
Department With Short-Term Clinical Outcomes
Weekes AJ, et al. Ann Emerg Med. 2026.