Published today in the journal Device, our collaborative paper titled, “Analysis and Management of Thermal Loads Generated In Vivo by Miniaturized Optoelectronic Implantable Devices,” consisting of equal parts experiment and theory, with additional content in animal model evaluations, all enabled by an interdisciplinary team of students and postdoctoral fellows in my group and the groups of Professors Yonggang Huang (
@NorthwesternU), Yevgenia (Genia) Kozorovitskiy (
@NorthwesternU),
@AvilaROAD (former jointly advised PhD student with Prof. Huang, now on the faculty at
@RiceUniversity), Abraham Vázquez-Guardado (former postdoc, now on the faculty at North Carolina State University) and
@YiyuanYang15146 (former PhD student, now on the faculty at National University of Singapore). At 22 pages of dense content, this paper is – in our view – a good example of academic rigor in the engineering science of bioelectronic systems. The results define essential, quantitative thermal considerations relevant to broad classes of active, miniaturized implantable devices -- with a focus on microscale light emitting diodes in filamentary probes for optogenetic studies that rely on behavioral studies of small, freely moving animals. An interesting side note is that this manuscript received detailed comments and strong, positive evaluations from six (!) different referees – an indication, perhaps, of some combination of interest in the content and dedication of the editors at Device! Of the >1000 papers that I’ve co-authored, only a small number (<5%) has received comments from six or more referees; in our experience, receiving even five referee reports is relatively rare (maybe ~10%). Thanks to everyone involved – the editors, the referees, the senior co-authors and, most importantly, the students and postdocs who did the bulk of the work: all of them, but most prominently Dr.
@MingzhengWu (postdoc in my group), Kaiqing Zhang (postdoc in Prof. Huang’s group, now on the faculty at
@CengJ17469) Priscilla Fok (visiting PhD student in my group from
@NTUsg),
@haohuizhang1994 (postdoc in Prof. Huang’s group) and Andrew Efimov (PhD student in my group)!