Joined May 2019
- Tweets 246
- Following 262
- Followers 262
- Likes 1,002
6 Photos and videos
Pinned Tweet
22 Jun 2023
I'm beyond excited to share the product of my dissertation, and the latest work of @CaluLab_Bmore, now published in @SfNJournals #JNeurosci
It’s got Pavlovian behavior, opto, eCBs, photometry, and dopamine (which of course is doing something unexpected)!
jneurosci.org/content/43/25/…
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Sam Bacharach retweeted
14 May 2025
Excited to share our newest paper led by @kuldeepshrivas3 out now in @NatureComms
nature.com/articles/s41467-0…
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Sam Bacharach retweeted
31 Dec 2024
The fireworks in your mind. 🧠✨ This sparkling video shows the neurotransmitter glutamate being released into synapses, made possible by an indicator developed by @abhi_aggarwal1, @PodgorskiLab, and team.
#HappyNewYear #NYE
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Sam Bacharach retweeted
7 Nov 2024
We found that in vivo peptide release and signaling gradually enhances the response of satiety-promoting hypothalamic neurons to each bite of food during a meal. These consequences of each bite take minutes to manifest, and could help explain why slow eating enhances satiety.
7 Nov 2024
I am thrilled to share the published version of our study on how neuropeptide signals regulate feeding in the hypothalamus! We imaged endogenous peptide signals in subcellular compartments during behavior. Below is an updated summary: rdcu.be/dZlI3
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Sam Bacharach retweeted
26 Sep 2024
Hey NRSA recipients, this is the heroine who your awards are named after 👇💕
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Evidence is mounting that blockbuster anti-obesity drugs might also curb alcohol cravings, and more. go.nature.com/3XT8NrM
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Sam Bacharach retweeted
1 Aug 2024
🚨 Glucagon-like peptide-1 (GLP-1) and substance use disorders: An emerging pharmacotherapeutic target
sciencedirect.com/science/ar…
@Lorenzo__Leggio @PharmacolRes @NIDAnews @NIAAAnews @IRPatNIH
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Sam Bacharach retweeted
1 Aug 2024
Be mindful about axon collateralization! We have changed some experimental strategies based on this discovery. Proud to have the cover image for this journal issue and also a “Featured Article” designation! Happy times.
jneurosci.org/content/44/31/…
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Sam Bacharach retweeted
10 Jul 2024
Today in @Nature--
@MonellSc researchers, led by @AmberAlhadeff, share new findings that point towards a possible way to reduce adverse side effects of popular next-generation obesity medications like GLP1-based drugs, known as semaglutide and marketed as Ozempic® and Wegovy®
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Sam Bacharach retweeted
10 Jul 2024
Drugs like Ozempic are great for weight loss, but they make some people feel sick. We discovered that the brain circuits mediating the appetite suppression are distinct from those that mediate nausea – a finding that may be leveraged to develop more selective GLP1-based drugs.
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Sam Bacharach retweeted
9 Jul 2024
A feature-specific reward prediction error (RPE) model: individual VTA #dopamine neurons report RPEs for different aspects of an animal’s situation, explaining heterogeneity in DA signals
@rachel_s_l @SagivYotam @nathanieldaw @IlanaWitten
nature.com/articles/s41593-0…
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Sam Bacharach retweeted
8 Jul 2024
@CaluLab_Bmore’s David Martin et al study officially is out 🎉, Psychedelic effects on Dopamine signaling:
nature.com/articles/s41386-0…
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Sam Bacharach retweeted
21 Jun 2024
How can some people - like meditators and free divers - control their own heart rates?? An impossibly cool paper where the answer comes from training rats 🐀 to regulate their 🫀
Top-down brain circuits for operant bradycardia | Science science.org/doi/10.1126/scie…
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Sam Bacharach retweeted
13 Jun 2024
New research from our group on differences between VTA glutamate neuron subtypes in their signaling of rewarding and aversive experiences
12 Jun 2024
Salience signaling and stimulus scaling of ventral tegmental area glutamate neuron subtypes biorxiv.org/cgi/content/shor… #biorxiv_neursci
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Sam Bacharach retweeted
21 May 2024
A fear conditioned cue orchestrates a suite of behaviors in rats
elifesciences.org/articles/8…
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Sam Bacharach retweeted
20 May 2024
Root lab is recruiting four research assistants to aid in stress-related research (jobs.colorado.edu/jobs/JobDe…) and ongoing projects (jobs.colorado.edu/jobs/JobDe…). Boulder is a great place to be, reach out if have questions!
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Sam Bacharach retweeted
13 May 2024
So excited to have our most recent #dopamine paper led by @_sjmillard and @ivybhoang out in @NatureNeuro today!
rdcu.be/dHL7l
15 Aug 2022
Beyond excited to have our new paper up on @biorxiv_neursci! Led by @_sjmillard, we reveal the cognitive basis of intracranial self-stimulation (ICSS) of midbrain dopamine neurons. biorxiv.org/content/10.1101/…
A 🧵
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Sam Bacharach retweeted
5 May 2024
From someone who has studied this field for over 2 decades, I can comfortably say that virtually everything said here is inaccurate. It is incredibly disturbing to me that someone claiming to be a scientist can talk with such authority on something they clearly know nothing about
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Sam Bacharach retweeted
3 Apr 2024
Something very very bad is happening to me or I am tired
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Sam Bacharach retweeted
1 Apr 2024
Check out recent work of @CaluLab_Bmore’s David Martin et al examining Psychedelic effects on NAc dopamine signaling of Pavlovian reward associations!
1 Apr 2024
The psychedelic, DOI, increases dopamine release in nucleus accumbens to predictable rewards and reward cues biorxiv.org/cgi/content/shor… #biorxiv_neursci
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Sam Bacharach retweeted
17 Mar 2024
A few days ago, the journal eLife published a self-study on the first year of its new publishing model, and it is well worth a look. Here are some notes based on my own experience with the journal as author and reviewing editor: markusmeister.com/2024/03/17….
29 Feb 2024
Thousands of authors have put their trust in our vision for publishing.
Today, we look back at the first year of our new model in numbers. 1/3
elifesciences.org/inside-eli…
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