🧠 Is creativity mostly just high intelligence? A new twin study in @ICAJournal says no. There’s a large genetically independent component. @timothycbates analyzed intelligence test scores and creativity data in three domains: business, military, politics/leadership). Key findings: ➡️Creative achievement is highly heritable (h² ≈ .56), shared environment ≈ 0 ➡️Latent creativity and general intelligence are genetically independent. ➡️g explains only ~10% of the genetic variance in creative achievement These findings support a hybrid view: g helps in many domains, but creativity has substantial unique genetic architecture. As Bates explains, "the genetic architecture of real-world creative achievement is not merely a downstream consequence of general intelligence but reflects a separate, heritable system that operates across artistic, scientific, and enterprising domains" (p. 6). Read the full open-access paper: doi.org/10.65550/001c.162501

Is this true? If so, what causes it to be true? x.com/eryney_ok/status/20630…

Interesting proof-of-concept for multiplex base editing in embryos. That said, we were surprised by the lack of optimization and benchmarking. The study does not explore guide stoichiometry, delivery parameters, RNA stabilization strategies, or next-generation ABE variants designed to improve editing precision and reduce bystander activity. We were also surprised by the comparison against Cas9 rather than against the current generation of adenine base editors. Finally, editing outcomes in MII-stage embryos cannot always be inferred from observations in HEK293 or hESC systems, making developmental context an important variable to consider. At Origin Genomics, we believe these questions are the real frontier. We're building experimental systems to systematically study how editor architecture, delivery, guide design, and developmental context influence editing outcomes in human embryos. The paper demonstrates feasibility. The more interesting question is how much further efficiency and precision can be pushed with systematic optimization.