The Betz Lab is interested in the mechanics of cellular systems especially concerning cancer progression, collective cell migration and cell fate decision.
If you want to literally play with a microscope, try our new LEGO based one: biorxiv.org/content/10.1101/…. Plans and multi-language guides to teach kids are on GitHub: github.com/tobetz/LegoMicros…. Sub-micron resolution thanks to a smartphone lens. Please RT, so that it reaches the kids!
Jochen Guck just passed away. He was not only a brilliant mind, amazing researcher, and outstanding person — he was also one of the best friends one could ever have. Jochen, you will be missed so deeply. Your spirit and laughter will stay in our hearts forever.
After 8 amazing months at the NYU/Center for Soft Matter Research I had to say goodbye😭to a wonderful group of colleagues and students. Thanks for the hospitality and patience in teaching me active swimmers and holographic tweezers🤩. Next thing to do: Setting it up in Germany💪
I am so proud. Dorian's poster was selected for the posterprize at this years spring meeting of the German Physical Society🥳. Well deserved 🫠. Three prizes by my students in three years. I am so lucky that I can call this talented crowd of passionate researchers the BetzLab 🤩
Getting tissue stress from images is tough, and elastic tension sensors are a way to solve this. Still, the analysis is complex. Try our GUI gitlab.gwdg.de/betzlab_publi… implementing analytical solutions to obtain surface stresses AND shape parameters of beads and nuclei.
You are a biologist and want to get an idea why looking at intracellular active mechanics is important for cellular function? Check out our recent review preprint: arxiv.org/abs/2501.14538
We try to give an intuitive access, but also provide details in extensive toolboxes.
Congrats to all the authors, especially Wolfram and Malte for an amazing work. The paper is a beautiful icing on the amazing achivement of the heart muscle patches! It's such a gamechanger!!
What a day! Perfect weather for the beautiful Göttingen tradition to give a kiss to the famous 'Gänseliesel'.🥳 Till was pulled to the fountain in a special cart and stepped in the footprints of many famous scholars by offering some flowers and a kiss to the statue 🤩.
Happy and exhausted after an amazing week of active cytoskeleton talks at the #WEH818 seminar in Bad Honnef. We had a whopping 44 talks, 33 posters, a 13km hike, and lots of incredible discussions. Congrats to the poster prize winners👇 and thanks to all for an amazing seminar🤩
The schedule of the #weh818 seminar on the cytoskeleton as active matter is as dense as the cytoskeleton itself, but we do not want to miss any of its great talks. Here a few pictures, from the talks by Francois Nedelec, Erwin Frey @PhysOfLifeLMU, Martin Lenz @lenz_lab and Gijsje Koenderink @BiosoftLab (who just joined the Royal Netherlands Academy of Arts and Sciences)
Amazing first day of the #WEH818 Seminar on the 'Cytoskeleton as Active Matter'. Besides the cool talks and fun discussions, we had an impressive lineup of Poster-Presenter Flash talks.
Congratulations to @LeonLettermann for winning this year‘s Klaus Arnold publication prize by the German Biophysical Society #DGfB#DGfB24 for his recent paper in @PNASNews on a geometrical theory for gliding motility 👍🎉🥇
Paper alert: nature.com/articles/s41563-0…@NatureMaterials introduces the “Mean Back Relaxation” which quantifies non-equilibrium from simple passive particle trajectories. Amazing theory (M. Krüger, G.Knotz) and experiments @MunkerTill to obtain cell mechanics by simple observation🧐
What a surprise goodbye from my group, showing up at the station. Best farewell ever 🥹🥰. Now they will have a productive 8 months, as I will not bother them with meetings, journal clubs and updates 🤔.
And I look forward learning about Active Droplets and Tweezers @nyu_csmr.🤓
Amazing week in the Alps during the combined lab retreat with the Gunawan and Raz lab. Not only top science and great hikes, but we all also made many new friends and create hopefully new collaborations🤩.
Preprint alert! We show that the electrical maturation of neurons is regulated by environmental mechanics in vitro & in vivo, and we identify a mechanotransduction pathway. A tour de force by Eva Kreysing et al, great collaboration with @ThoraKaradottir. biorxiv.org/content/10.1101/…
What a great PhD defense by Till, who earned highest distictions🤩. He developped a mechanical fingerprint that can be used to classify intracellular viscoelasticity and activity. On top he established a new way to get activity and mechanics from passive observation. SO PROUD🤓
Welcome to a new cohort of PhD students🥳. Jannis, Dorian and Noémie focus on intracellular mechanics, while Tim is about to combine AFM, Spinning Disk microscopy and micropipette aspiration in a single setup to disentangle the contributions of membrane and cortical tension. 🤩