Assistant Professor at UCLA in the Department of Biological Chemistry
Joined March 2019
- Tweets 235
- Following 735
- Followers 1,506
- Likes 1,552
18 Photos and videos
Feb 25
(1/5) How does glioblastoma maintain its immense heterogeneity? 🧠Two new companion papers from the Bhaduri Lab @UCLA now on @bioRxiv offer a lineage-resolved view of GBM hierarchies. Let’s dive in! 🧵👇
biorxiv.org/content/10.64898…
biorxiv.org/content/10.1101/…
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Feb 25
(4/5) Next: Meet the NVP (Neurovascular Progenitor) 🧬. This rare population co-expresses neural and perivascular programs. Using patient-derived lineage tracing, we proved NVPs can bridge the gap, giving rise to both neural and mesenchymal fates.
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Feb 25
(5/5) Why it matters: In vivo ablation of NVP-associated programs remodels the tumor and significantly extends survival. These studies move us from descriptive atlases to a mechanistic, targetable understanding of tumor organization. Check them out!
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9 Oct 2025
I'm incredibly proud to be a part of the V Foundation's new PSA campaign because they’re 💯% in for Victory Over Cancer®!
The V Foundation gives 💯% of every dollar donated directly to lifesaving cancer research—no exceptions.
I'm so honored to be on this team!
We’re 💯% in for Victory Over Cancer®. We need to give everything we’ve got.
That’s why the V Foundation gives 100% of every dollar donated directly to lifesaving cancer research.
Our new PSA campaign showcases the incredible team it takes to achieve Victory Over Cancer®, featuring Cancer Survivor @chauntelowe and V Foundation Grantee, @BhaduriLab.
Give đź’Ż% today: v.org/donate.
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24 Jun 2025
So excited to share this paper led by @ShivaniBaisi_MD! Check out iHOTT!!
23 Jun 2025
🧵Excited to share our new preprint introducing iHOTT - an autologous tumor-immune co-culture model that captures patient-specific responses in #Glioblastoma
💥Now on @biorxivpreprint: biorxiv.org/content/10.1101/…
đź“ťFrom @BhaduriLab in collaboration with @UCLANsgy
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6 May 2025
Excited to present our new preprint led by @claudianguyen95 uncovering how thalamic input shapes human cortical development! We discover that thalamic axons promote upper layer cortical neurogenesis through NRXN1-mediated contacts with outer radial glia. biorxiv.org/content/10.1101/…
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6 May 2025
Our findings suggest that the early entry of thalamocortical afferents in human and nonhuman primate cortex mediates communication with cortical progenitors. This demonstrates that the human thalamus actively sculpts cortical architecture during early development! 🧩
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6 May 2025
A huge thank you to the amazing collaborators and members of the Bhaduri Lab for their contributions to this study! Antoni Martija, @prnano9, @Jalbsoto, Dan Jaklic, @MilJessenya, Rista White, @JacquiMMartn1, Dakshesh Rana, @GeschwindLab
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Aparna Bhaduri retweeted
1 May 2025
📢 Paper out! FCDII is more complex than expected - somatic mTOR-activating mutations affect multiple cell lineages, yet only a fraction become cytomegalic. Dysmorphic neurons show mitochondrial dysfunction. #Epilepsy #BrainMosaicism #Neurodevelpment
30 Apr 2025
Single-cell genotyping and transcriptomic analysis reveals cell-type specific and non-autonomous effects of mTOR pathway mutations in mosaic focal cortical dysplasia type II (FCDII)
@BaulacS @SaraBaldassari4 @KlinglerEsther @InstitutCerveau
nature.com/articles/s41593-0…
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A new UCLA study leverages computational methods and existing data to bring us closer to answering the question: How does the brain build itself?
@dgsomucla
@UCLAHealth
@UCLAstemcell newsroom.ucla.edu/stories/cr…
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Aparna Bhaduri retweeted
29 Apr 2025
Parallel meta-analyses of the human cortex in development (seven datasets) and adulthood (16 datasets) generated over 500 gene co-expression networks describing of cortical development, centering on peak stages of neurogenesis
@BhaduriLab @prnano9
nature.com/articles/s41593-0…
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1 May 2025
Congrats @prnano9! We are thrilled that this paper is out, check it out!
1 May 2025
It’s out! The first paper from my postdoc – and first from the @BhaduriLab – is now live @NatureNeuroscience. 🧠✨ (1/5)
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Aparna Bhaduri retweeted
How does the brain build itself & how can this knowledge help fight brain cancer? A new @NatureNeuro study from the @BhaduriLab creates “meta-atlases” of the brain, revealing gene programs active in both development and brain tumors like glioblastoma.
bit.ly/4lS2sqr
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