🌟After an incredible 10 years, we bid a fond farewell to @DrRomanBelle as he embarks on an exciting new chapter! Roman’s contributions to our chemical biology research, his scientific insight and dedication have left a lasting mark on our work. 🌟

RT @YuanfenYang: Joint statement from myself and Abtisam Mohamed MP.

In our chem bio research groups, we are committed to fostering an inclusive environment where everyone can thrive and make a difference. Special thanks to all the women in the Kawamura Research Group and @mcallister_lab for their contributions to the field of science! #IDWGS2025

The cost of #Wegovy to prevent one stroke in the US is double what’s paid by Britain’s health service, reveals new analysis by Airfinity. Read our feature in @Bloomberg to find out more. bloomberg.com/news/articles/…

Join our @ScienceUnga Webinar: Data for Pandemic Preparedness: New approaches for medical countermeasure (MCM) delivery Live next Wednesday 18th September 2024, 3pm ET/ 8pm BST. Register for free through the UNGA Science Summit online portal below. sciencesummitunga.vfairs.com…

Today I finally got to witness chaos with Ed Miliband. Quite orderly actually. Don't forget your photo ID when you vote #Labour on July 4th. It's rose season 🌹🌹🌹🌹🌹

Compass Oxon had a fabulous day yesterday campaigning in Banbury for voters to support @UKLabour candidate, @SEANLWOODCOCK. Bravo and a huge thank you to everyone involved. #WinAsOne

This weekend, Airfinity is at #ACC24, @ACCinTouch's annual scientific conference. Get in touch via obesity@airfinity.com if you would like to get a free briefing with our Chief Medical Officer @hsillesen and Senior Director @BhaskarScience

Today, @VerveTx is announcing updates to our PCSK9 program: 1. voluntarily pausing enrollment in the Heart-1 trail of VERVE-101 2. prioritizing clinical development of VERVE-102 which uses a different LNP delivery system 3. announcing clinical trial application have been cleared in U.K. & Canada for Heart-2 trial of VERVE-102 4. expect initiation of Heart-2 trial this quarter Details: 1. 13 patients dosed so far in Heart-1 trial, 6 at 0.45 mg/kg dose 2. Efficacy: up to 73% reduction in LDL-C and durability out to 270 days after single treatment 3. However, at potentially therapeutic doses, seeing laboratory abnormalities 4. last patient dosed at 0.45 mg/kg experienced a Grade 3 drug-induced transient increase in serum alanine aminotransferase as well as a serious adverse event of Grade 3 drug-induced thrombocytopenia (a drop in the platelet count) 5. Lab changes transient, reversible, asymptomatic 6. Nevertheless, have elected to pause enrollment to investigate in order understand mechanism, if means to mitigate 7. Regulators informed; IND, CTAs for Heart-1 trial remain active 8. We believe lab safety findings attributable to lipid nanoparticle delivery system 9. For now, prioritizing development of VERVE-102 10. VERVE-102 uses an LNP with an ionizable lipid that has been tested in third-party clinical trials and well-tolerated 11. VERVE-102 also adds a GalNAc liver-targeting ligand 12. Expect to start Heart-2 trial of VERVE-102 in 2Q '24 Link to PR: ir.vervetx.com/news-releases…

Had an excellent time at the @BriTANicK show yesterday at the @sohotheatre! An absolutely fantastically crafted show, go see them if you get the chance! Also, bonus run-in with @TheJacobTrueman of the Fratocrats :)

UK plant science twitter, can you help? Is anyone growing whole cell Arabidopsis thaliana cultures and would be happy to share some with us? Ours sadly died but we need some for more experiments! Many thanks :-)

Very exciting to see @KlemSimelis’ #phdresearch on targeting TET #enzymes using #cyclicpeptide inhibitors in #Bioorganic & #MedicinalChemistry! A great collaboration with the Suga group & @SchofieldOxford. Read Klem's paper online: sciencedirect.com/science/ar… #chemicalbiology

📣 Applications now open for a funded #PhD #chemicalbiology #cyclicpeptides. Exciting opportunity for doctoral research with the Kawamura Research Group and @MosmedC at Newcastle Uni @ChemistryNCL, in collaboration with @novonordisk. More information: ncl.ac.uk/postgraduate/fees-…

Congratulations @DrRomanBelle on this paper in Journal for Medicinal Chemistry regarding new means for investigating TET #enzymes, and thanks to our collaborators @Prof_Tom_Brown, @SchofieldOxford, @sk_kriaucionis and Nicola Burgess-Brown. @OxfordChemistry @ChemistryNCL

Women, nb, and under-represented people of colour are welcome to DM me if they have any questions about standing for election. We have a supportive team here in Banbury 🌹

The Fabians have our seat of Earley and Woodley as the crucial marginal Labour needs to win for a majority. If you want a change of government, turn up to make it happen: DM me, or find our next campaign event at yuanforearleyandwoodley.org/…

Seeing adverts for super competitive Junior Research Fellowships at Oxford. The salaries don’t make the cut for the minimum wage required for a skilled worker visa- people should realllyy think twice before they start moralising about potential career options to intl students ✋

Thank you @KawamuraGroup and @TPSmithSci for your boundless support and energy in getting this paper over the line! P.S. It was about time I changed my Twitter handle to a more professional one :D