Joined March 2017
- Tweets 56
- Following 680
- Followers 146
- Likes 1,022
1 Photos and videos
Conor Walker retweeted
2 Oct 2024
Super excited to share my lab's latest work on quantifying the private information leakage from single cell count matrices. Led by very first postdoc in the g2lab, brilliant @BioConorWalker, we showed that individuals can be reidentified 1/n cell.com/cell/fulltext/S0092…
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Conor Walker retweeted
9 Apr 2024
If you were looking for evidence that isoforms are cool, all-pervasive in the 🧠, and everybody should study them at the single cell level, our work on mouse development and brain-region variability from the @hagentilgner lab is now live @NatureNeuro! 1/
nature.com/articles/s41593-0…
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Conor Walker retweeted
20 Jul 2022
A few months ago we posted a pre-print regarding a new approach to likelihood-based phylogenetics at short divergence scales (e.g. genomic epidemiology). I have now further optimized the code and updated the preprint doi.org/10.1101/2022.03.22.4…
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Conor Walker retweeted
10 Jul 2022
We've made a draft human pangenome! 47 haplotype-resolved assemblies, two reference genomes, and five pangenome graphs!
ALT Structural haplotypes of HLA-A in the PGGB HPRCy1 graph
10 Jul 2022
A Draft Human Pangenome Reference biorxiv.org/cgi/content/shor… #bioRxiv
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Conor Walker retweeted
27 May 2022
This is a brilliant preprint. It describes an experimental method for separately sequencing the paternal and maternal genomes. This goes beyond the standard "experimental phasing" - the method can also tell which chr is maternal and which is paternal.
biorxiv.org/content/10.1101/…
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Conor Walker retweeted
9 May 2022
We've known for a long time that a large fraction of noncoding GWAS hits are not currently explained by eQTLs. Why?? I'm excited to share our new preprint on this! Take home: GWAS and eQTL assays maximize power for different types of variants. (1/n)
biorxiv.org/content/10.1101/…
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Conor Walker retweeted
23 Mar 2022
Groundbreaking work from @Nicola_De_Maio @EBIgoldman and colleagues
"we rewrite the classical Felsenstein pruning algorithm so that we can infer phylogenetic trees on at least 10 times larger datasets with higher accuracy than existing maximum likelihood methods. "
23 Mar 2022
Maximum likelihood pandemic-scale phylogenetics biorxiv.org/cgi/content/shor… #biorxiv_bioinfo
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Conor Walker retweeted
16 Mar 2022
Really chuffed to share our latest work from Sanjana Lab out in @nature today (nature.com/articles/s41586-0…).
We tested >12,000 genes to find positive regulators of T cell proliferation to be used for next-gen #immunotherapies.
A thread...
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18 Jan 2022
Looking forward to starting my new position with @gamzeandgursoy at @nygenome! I will be working on developing methods for genomic #privacy.
g2lab.org/people/
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18 Jan 2022
A huge thank you to @Nick_Goldman, @aylwyn_scally, @Nicola_De_Maio, and members of @EBIgoldman for their supervision and support during my #PhD.
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Conor Walker retweeted
24 Sep 2021
Simulating pandemic-scale genome sequencing datasets, e.g to benchmark your new analysis methods? Try phastSim, now updated to include indels (biorxiv.org/content/10.1101/…)
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Glad to see this out. Here, we track ~700 clones across >300 individuals over ~13 years to unravel key aspects of clonal haematopoiesis (when there are genetically-defined subpopulations of haematopoietic stem cells in your bone marrow).
13 Aug 2021
The longitudinal dynamics and natural history of clonal haematopoiesis biorxiv.org/cgi/content/shor… #bioRxiv
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Conor Walker retweeted
6 Aug 2021
Congrats to the 2021 @EvolComp Talk & Poster awardees for #ismbeccb2021
Best talk - Elise Parey (@CamLBerthelot lab)
Best poster - Vignesh Sridhar (@Vigs_24, @JRaviLab)
Honorable mentions
Talks -
@punto_c
@BioConorWalker
@matteodelabre
Posters - @elliotmajlessi
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Conor Walker retweeted
3 Aug 2021
We are still looking to hire a postdoc bioinformatician on this fascinating project. Please read/RT/pass on to anyone who might be interested:
x.com/emblebi/status/1422516…
🎉 Congratulations on recent @EU_Commission @HorizonEU funding awarded to researchers at @IITalk, @uni_lu, @CNRS, @UniPadova and EMBL-EBI’s @EBIgoldman and colleagues. Find out more 👇
ebi.ac.uk/about/news/press-r…
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Conor Walker retweeted
15 Jul 2021
We are re-advertising this position! Please check-out 👇 the original thread 👇, pass to anyone you think might be interested, share with colleagues, RT ...
x.com/EBIgoldman/status/1384…
20 Apr 2021
Postdoc position in @EBIgoldman Group at @emblebi, to join new multinatl collab project creating proof-of-principle high-throughput nanopore device for determining amino acid sequence and identity of proteins
Full details at embl.org/jobs/position/EBI01…
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Conor Walker retweeted
11 May 2021
The impressively huge scale of SARS-CoV-2 sequencing has really stretched our ability to do phylogenetics, and is leading to some fantastic advances in methods. Here's one that @Nicola_De_Maio from the @EBIgoldman group at @emblebi contributed to.
x.com/emblebi/status/1392006…
#SARSCoV2 is spreading through human populations & evolving. Ultrafast Sample placement on Existing tRees (UShER) is a game-changing new tool which can be used to track this evolution in real time & reconstruct the source of new cases. @NatureGenet @ucsc
nature.com/articles/s41588-0…
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Conor Walker retweeted
7 May 2021
Last call; closing date on Monday. Please apply! If you don't apply, at least promise me you'll RT or pass to a friend.
x.com/EBIgoldman/status/1384…
20 Apr 2021
Postdoc position in @EBIgoldman Group at @emblebi, to join new multinatl collab project creating proof-of-principle high-throughput nanopore device for determining amino acid sequence and identity of proteins
Full details at embl.org/jobs/position/EBI01…
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Conor Walker retweeted
20 Apr 2021
Postdoc position in @EBIgoldman Group at @emblebi, to join new multinatl collab project creating proof-of-principle high-throughput nanopore device for determining amino acid sequence and identity of proteins
Full details at embl.org/jobs/position/EBI01…
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Conor Walker retweeted
19 Mar 2021
For those of you who love to explain complex mutation clusters parsimoniously (who doesn't?), the final version of @BioConorWalker's paper is now out at journals.plos.org/plosgeneti… - also feat. @aylwyn_scally and @Nicola_De_Maio. And me. Cool figures too: this 👇 is part of S.Fig 10
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Conor Walker retweeted
18 Mar 2021
We developed a new method (phastSim) to simulate sequence evolution along huge phylogenies, in particular pandemic-scale ones like in SARS-CoV-2 doi.org/10.1101/2021.03.15.4… with @EBIgoldman @RussCorbett @BioConorWalker @weilgunyl @yatishturakhia
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