Research lab at the University of Adelaide with a focus on structural biology, protein chemistry, drug discovery, and enzymology

Joined July 2018
34 Photos and videos
Was lucky to meet up with former PhD students from BruningLab: Andrew Marshall (UWA), Andrew Thompson (Oxford/WEHI) and Jordan Pederick (UA)
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Congratulations @StephNguyenPhD and good luck on all future protein preps. I’m sure there will be many.
Ayyy the letter has arrived! Ya girl is officially #PhDone A quick moment of celebration in the lab before I get back to my protein prep 🥲 @UniAdelSciences @BruningLab
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Congratulations Dan on delivering a great poster! Very well deserved!
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A brand new review written by @FrkicRebecca sheds light on how we can treat type 2 #diabetes by inhibiting PPARy phosphorylation
"The therapeutic potential of inhibiting PPARγ phosphorylation to treat type 2 #diabetes" @UniofAdelaide @FrkicRebecca #JBCReviews #drugdesign qoo.ly/3dmtmj
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Some fantastic work from @acmarshallphd from his time in Adelaide
By tweaking this #enzyme in only a handful of places we made it activated by K ions… some #proteins are remarkably engineerable! @BruningLab portlandpress.com/biochemj/a…... (1/3)
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Bruning Structural Lab retweeted
Latest work from the lab is published doi.org/10.1002/chem.2021027… #biocatalysis, #ozchem, #P450s Lead by Master students Rebecca @RebeccaChao29 and Ian @LordOfSpatulas @AdelaideChem @UQ_SCMB
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Bruning Structural Lab retweeted
🔥 New advance article for RSC Chemical Biology! 🔥 Andrew Abell, @BruningLab et al @UniofAdelaide exploring a cell permeable bimane-constrained PCNA-interacting #peptide! #chembio #bimane 🧐 Read the #TransparentPeerReview #OpenAccess article 👉ow.ly/6cEG50FIwyp
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That’s a wrap for @StephNguyenPhD who gave her completion seminar last week. She’s off to @WEHI_research to continue on her structural biology journey. Best of luck!
It's been an absolute pleasure having you @StephNguyenPhD as a student with the @BruningLab ☺️ Super happy for you!!! @WEHI_research is going to be very lucky to have you!!! 🎉🎉💪💪 @AdelaideProtein @UniAdelSciences
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Exciting work coming from @StephNguyenPhD. Read the preprint on @biorxivpreprint!
So excited to be part of this work on #SARSCoV2. Available to read on @biorxivpreprint! biorxiv.org/content/10.1101/…
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Bruning Structural Lab retweeted
Another year, another synchrotron trip! ⚡️💎
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Bruning Structural Lab retweeted
New work from My lab and collaborators at UQ on understanding the mechanism of stereoselective P450 catalysed epoxidations pubs.acs.org/doi/10.1021/acs… #ozchem #P450 @AdelaideChem @UQ_SCMB
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A comprehensive review written by @StephNguyenPhD and @TruongJia - an interesting read for #antifungal enthusiasts
Aaand it’s published! I’ve written a review for @FrontMolBioSci with @TruongJia and @BruningLab that discusses exciting and unconventional fungal 🍄 pathways we could be targeting in our search for new #antifungal #drugs 💊 frontiersin.org/article/10.3…
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Some fresh #aspergillus research from @StephNguyenPhD published in @FEBSJournal - a tremendous amount of work to elucidate the structural determinants of nucleoside selectivity of the enzyme, nucleoside-diphosphate kinase
My 1st first author paper is out! A paper I’m so proud of because I learnt everything I now know about crystallography from this protein 💎 big thanks to our collaborators @blagojce11 @PukalaLab @BruningLab onlinelibrary.wiley.com/shar…
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Congratulations to @FrkicRebecca on submitting her PhD thesis! Wishing her all the very best for the future 💕
I have just submitted my PhD thesis at @UniofAdelaide! Shout out to those legends who have made my experience amazing. This journey has been so incredible and I am so excited for what is next to come!
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A snapshot of some of the exciting projects we have been working on using #proteincrystallography
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A new publication from @StephNguyenPhD from her time in the Booker Lab that started her work on #fungi and #antifungals with Dr. Sternicki and Dr. Polyak. Check it out! authors.elsevier.com/a/1bUOT…

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Soaking up some sun and enjoying Christmas lunch with the Bruning family 🌲☀️
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An insightful review written by @aimeehorsfall from #AbellGroup for anyone interested in #peptidomimetics, cancer therapeutics and #PCNA
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A Bruning reunion! Always nice to catch up with @acmarshall88, especially at @ITSASBMB!
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The latest in #PPARgamma research as we work towards developing improved anti-diabetic drugs
Thanks to @AdelaideProtein I was able to present some of my work at the @ITSASBMB conference in sunny Fremantle today! #ASBMB2019
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