We are thrilled to share that our first paper from my new lab, Spateo (github.com/aristoteleo/spate…) for spatiotemporal modeling of molecular holograms, is now online in Cell: cell.com/cell/fulltext/S0092…. Spateo is a comprehensive analytical framework for 3D whole-embryo spatiotemporal modeling. Its advanced features include: • 3D alignment and reconstruction at the whole-mouse-embryo scale (see the animation). • 3D spatial domain digitization and cell-cell communication analysis to understand spatial gene expression gradients and both inter- and intracellular communication. • 3D morphometric and volumetric analyses along with 3D morphogenesis vector field modeling to quantify dynamics such as surface area, volume, and cell density across organs, and to dissect the interplay between morphogenesis factors and cell migration. • A “Google Earth”-like browser, Spateo-viewer (viewer.spateo.aristoteleo.co… and github.com/aristoteleo/spate…), for interactive and intuitive exploration of 3D spatial data. • Additional features, such as RNA signal-based single-cell segmentation. We are also honored that Nature “News and Views” has highlighted this work as well: nature.com/articles/d41586-0…. This is really an amazing outcome after two years' heroic revision process that rewrite the entire paper using a new data (doi.org/10.1101/2024.08.17.6…) for whole mouse embryos.

Finally out 😃! Many thanks to all the contributors ! @crcl @iNeuroMyoGene @NatureComms nature.com/articles/s41467-0…

A Master internship (2nd year) in the lab starting from October 2024 for 10 months. Please spread the news. More informations below graduate-plus.fr/files/2024/…

Absolutely thrilled to announce that our superstar @benjaminvi99309 successfully defended his thesis ! 🌟👏 I'm immensely proud of his hard work and dedication. A heartfelt thank you to the jury members for their invaluable support and insights. #ProudPI @crcl @eddpasquier

#southROCK Avec 1000 personnels de recherche, les 2 plus grands centre de recherche en cancérologie français, le @crcl et le @crcm_marseille sont très fiers de faire partie de ce formidable projet. Ensemble nous serons plus fort dans la lutte contre les cancers pédiatriques !💪

*** on recrute ! / we're hiring ! *** Please share

📢 We are hiring a highly motivated postdoc in bioinformatics/genomics to join us in @institut_curie and beautiful Paris! Reach out if you want to decipher the spatio-temporal origins of pediatric brain tumors🧠 Please RT and spread the word!! 🤞

Please RT ! 3-year postdoc position open in my 🎗️KidsCaN team @CDB_lab @crcl @ERC_Research to work on the #ERCStG CANEUTREAT project and decipher neuro-cancer dialogs in pediatric malignancies of the peripheral nervous system #neuroblastoma #Pediatrics #cancer #neuroscience #job

We are recruiting a highly-motivated PhD student to join @INMG in Lyon. This fully-funded PhD position is starting in January 2024. Apply if you’re interested in epigenetics and muscle stem cell fate. Please RT. @MYOTWlTTER and @STEMCELLTech

Happy to share this fantastic news for the #CDB_lab 🤩🤟! We've been awarded a #ERCStG to decrypt the dialogs between young neurons and #PediatricCancers of the peripheral nervous system, #neuroblastoma. So proud of my wonderful #KidsCaN team🎗️@CRCL. #CancerNeuroscience @CNRS

We're hiring ! 🎗️A postdoc position is open in our team @CDB_lab @crcl Come and join the KidsCaN team to work on neuroblastoma dialogs with the bone marrow niche ! #neuroblastoma #Pediatrics #CancerNeuroscience

Exciting new #CancerNeuroscience paper from Ben Deneen’s group ⁦@bcmhouston⁩ @bcm_neurosci⁩ , uncovering neuronal activity-regulated paracrine signaling from long range projections to #glioma that promotes tumor invasion. 🧠 nature.com/articles/s41586-0…

1/ We're thrilled to share our preprint on Deep3P - a new approach that takes us on a deep dive into the world of brain tumors, using three-photon microscopy and #AI. This exciting endeavor is brought to life together with the amazing @Prevedel_Lab ! tinyurl.com/mpz3extr

Please RT: We are 🔥recruiting a post-doc 🔥to work on an exciting proof-of-concept project aiming at manipulating tumor cell trajectory by silencing microRNA modules. @IBDMmarseille emploi.cnrs.fr/Offres/CDD/UM…

Les chercheurs du réseau experts du #Neuroblastome se retrouvent au congrès international #ANR2023 “Advanced in Neuroblastoma Research” à Amsterdam. L’opportunité de renforcer les liens entre nos laboratoires et de diffuser nos travaux de recherche. #R4KatANR

The #CancerNeuroscience Symposium 2024 @MDAndersonNews is now open for registration! tinyurl.com/2p7s5m94

Don´t forget to register for the Heidelberg Conference on Cancer Neuroscience: cancerneuroscience.de/confer… Learn more about this emerging field of research and discuss its hottest topics and clinical implications.

I don’t usually post personal news but Clinicians have told us to pull every lever. Our daughter has with #dipg Brain cancer. There is no cure and typically 9m life expectancy. If anyone knows of trials then please get in contact! #braincancer #childrenscancer @CR_UK

Aujourd'hui, c'est la journée mondiale des cancers pédiatriques. Pour soutenir les enfants et les jeunes qui se battent contre la maladie, et ensemble faire reculer le cancer, je joins ma voix. #jejoinsmavoix #InternationalChildhoodCancerDay