Associate Professor @Aarhusuni. Trying to understand how RNPs shape transcriptomes and proteomes to impact cell biology.

Joined August 2016
8 Photos and videos
Christian Damgaard retweeted
Our paper on Stopless-ORF Circular RNAs (socRNAs) is now out in Cell. By high-res tracking and comparing translation by either single or multiple ribosomes, we find that ribosomes cooperate to overcome pausing to ensure fast and efficient translation cell.com/cell/fulltext/S0092…
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Christian Damgaard retweeted
Please SHARE: we are looking for a postdoc to study synaptic Calcium homeostasis and its dysfunction in Parkinson’s. Deadline: Nov 20, 2024 @dandrite @MolBiolAU @AIAS_dk @NordicEMBL au.dk/om/stillinger/job/full…
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Christian Damgaard retweeted
We in the Department of Molecular Genetics at Ohio State are looking for a new colleague in the areas of Cell Biology, Development Biology, or Genomics: osu.wd1.myworkdayjobs.com/OS…

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Christian Damgaard retweeted
Our new paper! mRNAs play structural roles in the cytoplasm. The longest mRNAs bound to FXR1 generate an mRNA-protein assembly that plays an essential role in cellular signaling by enabling proximity of proteins without RNA binding domains. cell.com/cell/fulltext/S0092…
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We report that circular RNA circHIPK3 sequesters IGF2BP2 to regulate cancer targets. Surprisingly, this is possible even though circHIPK3 is outnumbered by orders of magnitude by its client protein. Great collab with @TrineLineOkholm and @skouped doi.org/10.7554/eLife.91783.… 👇
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We suggest that circHIPK3 may nucleate several copies of IGF2BP2 per circRNA molecule, likely via phase separation. More speculatively, only a small fraction of IGF2BP2 may be available for RNA binding or an enzymatic modification of IGF2BP2 may take place on the circRNA.
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Finally, we find no evidence that circHIPK3 functions by tethering miRNAs, as has been suggested by numerous studies mostly based on circRNA overexpression, expression of miRNA mimics and/or miRNA reporter assays. @MolBiolAU
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Christian Damgaard retweeted
We now open a fully-funded postdoc position ⁦@dandrite⁩ ⁦@NordicEMBL⁩ ⁦@MolBiolAU⁩ to study synaptic homeostasis using cutting-edge single-molecule/live-neuron imaging techniques. Please retweet! Application Deadline: Sept 6th au.dk/om/stillinger/job/full…
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Christian Damgaard retweeted
Very proud to share this paper in Nature today. nature.com/articles/s41586-0… A screen that lead to a completely unexpected regulatory mechanism linking soil nitrogen to the function of legume nodules. A great collaboration with @JieshunLin @PeteBork Marie, Kasper and many others
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Christian Damgaard retweeted
Jeg er forbløffet over den naivitet, som @RStoklund @sofielippert og minister @ChristinaEgelun lægger for dagen her. Reformen er en katastrofe. Det var den sidste år, og det er den også om et halvt år. I har stillet en umulig opgave på et fejlagtigt grundlag. Held og lykke 🤷
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Christian Damgaard retweeted
We’re excited to share our study in @CellCellPress on the role of the MAP3 kinase ZAK in UV-induced apoptosis led by @2primehydroxyl! We studied cell signaling kinetics following UV-damage and found that ZAK drives apoptosis via ribosome collisions. cell.com/cell/fulltext/S0092…
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Christian Damgaard retweeted
25 Apr 2024
#Postdoc position available to investigate the neurobiology of sleep as NORPOD fellow of ⁦@NordicEMBL⁩ with me ⁦@dandrite⁩ ⁦@MolBiolAU⁩ and ⁦@ChaBoccara⁩ ⁦@NCMMnews⁩ Deadline: May 31st, 2024. Apply here: job.jobnet.dk/CV/FindWork/De…

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Christian Damgaard retweeted
19 Mar 2024
8 Mar 2024
Today marks #InternationalWomensDay all over the world. In #neuroscience, there is also a battle worth fighting. On 22 March we are happy to host a panel discussion on the topic with Prof. Erin Schuman, Prof. Marina Romero-Ramos & Clin. Prof. Ida Vogel. 📹It will be live streamed
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Christian Damgaard retweeted
10 Mar 2024
8 Mar 2024
Today marks #InternationalWomensDay all over the world. In #neuroscience, there is also a battle worth fighting. On 22 March we are happy to host a panel discussion on the topic with Prof. Erin Schuman, Prof. Marina Romero-Ramos & Clin. Prof. Ida Vogel. 📹It will be live streamed
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Christian Damgaard retweeted
Very excited to share our paper out today in @naturemethods, introducing TREX (Targeted RNase H-mediated Extraction of X-linked RBPs), a novel approach to reveal proteins that bind to any region of any RNA molecule of interest in living cells🧪: rdcu.be/dyZ2c (1/10)
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Udfordrende men spændende øvelse at formidle forskning bredt - især når der ikke kan bruges illustrationer. Chapeau til @DFF_raad Kasper Friis @videnslyd . #dkforsk @MolBiolAU
🎧PODCAST: Vidste du, at vores celler rammes hårdt, når vi får den frygtede sygdom ALS? Hvad der går galt og hvorfor, er et mysterium som @CKDamgaard fra @AarhusUni forsøger at opklare, så vi i fremtiden kan forhindre og behandle flere sygdomme👇#dkforsk dff.dk/ansog/stottet-forskni…
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Christian Damgaard retweeted
Happy to share the publication of our paper in @Nature Conformational ensembles of the human intrinsically disordered proteome Work led by @GiulioTesei and @AnnaIdaTrolle. I'll post more later, but for now here is a link: nature.com/articles/s41586-0… and a short movie about the work
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Christian Damgaard retweeted
A 3 year postdoc position in bioinformatics and cancer genomics is available in the @LDyrskjot team with focus on translational bladder cancer research and identification of biomarkers for treatment response and outcome using tumor profiling and ctDNA. au.dk/om/stillinger/job/post…
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