Caitlyn Holmes. Incoming Assistant Professor at the U of Minnesota studying Klebsiella-host interactions. Postdoc: Bachman Lab. Alum: UW-Madison, UCF. #KlebClub

Joined January 2011
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An Update! πŸŽ‰ I am so happy to announce that in May 2025, I will be joining the University of Minnesota as an Assistant Professor in the Department of Microbiology & Immunology. My lab will study host-pathogen interactions during Klebsiella systemic infection.
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I'm excited to announce our latest publication! We teamed up with @KHullahalli to barcode Klebsiella and ask basic questions about bacteremia pathogenesis: 1) how are bacteria shared between sites and 2) which host and bacterial factors influence dynamics? nature.com/articles/s41467-0…
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Klebsiella leaves the lung in two distinct patterns, termed "metastatic" and "direct", which are defined by the extent of clonal replication in primary tissues and predict bacterial burden across sites. Oxidative stress from the host and bacterial LPS influences these patterns.
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Thank you to all collaborators for helping to sort through this huge set of data and to the barcoding community for your help in comparing our trends to other systems! This is truly a study were I made friends and collaborators along the way. ⭐
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It's that time of year! Registration and abstract submission for the 6th Klebsiella Seminar Series is now open. Participation is free and abstracts are due by February 16th. See the link below for details: forms.gle/gxbvaC6FjzuSPtjD9 #KlebClub

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Caity Holmes retweeted
I'm so happy that this paper is finally published! This one was a long time coming: 9 years, 3 pairs of hands, 270 strains, 93 plasmids, and a lot of hard work. It started as a side project that eventually led to my entire dissertation, and I'm glad it did.
Superb @mSystemsJ study by @RuthlessRuth15 et al from @markjmandel Functional analysis of cyclic diguanylate-modulating proteins in Vibrio fischeri "protein OE to systematically characterize the functional potential of all 50 V. fischeri proteins"❗️ journals.asm.org/doi/10.1128…
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New article!✨In this review, we present a broad overview of bloodstream infections, consider microbial pathogenesis mechanisms, and discuss how these strategies could be used in future therapies. #KlebClub
Bloodstream infections: mechanisms of pathogenesis and opportunities for intervention Holmes, Bachman & co. explore major pathogens causing bloodstream infections, their pathogenesis, opportunities for prevention, diagnosis & treatment options.
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Caity Holmes retweeted
#KlebClub planning is back in session with our TWO NEW MEMBERS!!! Make sure to send a big congrats to Juan Valencia and @tomstantonmicro!!
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Caity Holmes retweeted
Great @GordonConf for #KlebClub! Safe travels to all, especially those dealing with flight delays and cancellations!
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β€οΈπŸ¦ πŸ™ŒπŸ’… Great science and great friends!
#KlebClub spotted in the wild! It was a beautiful day for a hike at @GordonConf with @az1980micro, @CL_Holmes, @KHullahalli, and @VornhagenLab!
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Caity Holmes retweeted
Excellent #KlebClub meetup at #ASMicrobe! It was great to see everyone in person! Let's keep growing this awesome community!
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An Update! πŸŽ‰ I am so happy to announce that in May 2025, I will be joining the University of Minnesota as an Assistant Professor in the Department of Microbiology & Immunology. My lab will study host-pathogen interactions during Klebsiella systemic infection.
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This has truly been an exciting process, and I have been supported (from the very beginning) by an all-star team of mentors, collaborators, and coworkers. A big thank you to everyone who has helped make this a reality!
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Caity Holmes retweeted
Hey #KlebClub! Are you going to #Microbe2024? Join us for our #KlebClub get-together πŸ‘‹ on Friday from 5-6 PM! If you plan on attending, please reply with the number of folks there so we can plan accordingly!

ALT Happy Dog GIF by GIPHY Studios 2021

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Come join us on the @KlebClub Organizing Committee! This community is a great way to engage with others in the field, and the committee is very flexible and supportive. Feel free to contact us if you have any questions.
KlebClub is looking for additional members to join our organizing committee!πŸ§ͺ Specifically, we are seeking 1-3 graduate and postdoc trainees to assist with new a community engagement initiative. If you are interested in joining, see the link below! πŸ‘‡ forms.gle/JtYamucXrb9Wsqs57
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So excited to share news of my K99 NOA from @NIAIDFunding! This award will allow me to expand my interests in Klebsiella pathogenesis and host-pathogen interactions during bacteremia, and I am thankful to continue this work into future projects.🦠
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There are many people to thank for their support - I am fortunate to work with mentors who are dedicated to trainee success. Particularly, I want to highlight @Bachman_Lab, @andolive85, and @bmoore_beth for their encouragement starting all the way back at the first draft. πŸ™Œ
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Caity Holmes retweeted
Get ready for Session 3️⃣ of #KlebClub ! Tons of #phages S Federici @sary82 will be our keynote & present her work from the @Elinav_Lab , followed by @DaniRothschild presenting @KlebPhaCol, and finally Aimee Tan from @UniMelbMDHS
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A perfect day! β˜€οΈπŸŒ˜πŸŒŽ
Total eclipse of the Mike Lab et al @microbioSaroj @rmwooten66 @CL_Holmes @MelanieMPearson
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New pre-print up today! We used bacterial barcoding to measure infection kinetics during bacteremia initiation from the lung. This collaboration was so fun (@KHullahalli and @kg_dailey) and the results were unexpected!
Patterns of Klebsiella pneumoniae bacteremic dissemination from the lung dlvr.it/T52qZt
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The fifth Klebsiella Seminar Series starts on Thursday! Join us to learn from our community about the latest Klebsiella research. Registration is still open!
It's time! Klebsiella Seminar Series starts this week!🌟We are thrilled to announce the 2024 program and are excited to hear the latest Klebsiella research. #KlebClub🦠See you on Thursday! Registration is free and still live at: sites.google.com/view/klebcl…
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