10 Photos and videos
We did it! First CPPopt feasibility and safety trial!
Results are here doi: 10.1089/neu.2021.0197
Is precision medicine in #TBI in #CriticalCare feasible? CPPopt as an individualised dynamic CPP target for protecting the brain.
Thanks #COGiTATE team for this work!
23 Aug 2021
The Autoregulation-Guided Cerebral Perfusion Pressure after Traumatic Brain Injury (COGITATE) results have been published!! @AriErcole @DrSmielewski @Menon_Cambridge @TasJeanette @iccvanderhorst @joseph_aotearoa @pja_hutch @erta_beqiri @GMeyfroidt
Link: lnkd.in/dfjp-WDH
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CPPopt retweeted
25 Nov 2024
The President’s Commendation for a sustained contribution to the College was presented to Dr Rana Hafiz Ur Rehman.
Dr Ari Ercole gave the Macintosh Professor Lecture. Seen here with President Dr Claire Shannon and Prof Iain Moppett.
Read more: ow.ly/NsKo50UeHFx
ALT HRH The Princess Royal presenting the President’s Commendation to Dr Rana Hafiz Ur Rehman.
ALT Dr Ari Ercole holding a certificate for the Macintosh Lecture with President Dr Claire Shannon and Professor Iain Moppett.
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CPPopt retweeted
8 Jan 2024
Wonderful news for a remarkable colleague, friend, and doctor.
8 Jan 2024
Following recommendations from @NIAAResearch, we are pleased to announce that 2 Macintosh Professorships have been awarded.
@RonelleMouton - RCoA & VASGBI Macintosh Professor
@AriErcole - RCoA Macintosh Professor
Congratulations both.
ow.ly/4W9m50QoPzW
ALT Pictures of Dr Ronelle Mouton, Honorary Associate Professor of Anaesthesia, Translational Health Sciences, Bristol Medical School and Dr Ari Ercole an anaesthetist and intensive care physician, holding a substantive consultant post in neuroscience and intensive care medicine at Cambridge University Hospitals NHS Foundation Trust.
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CPPopt retweeted
15 Nov 2023
Traumatic brain injury #TBI phenotypes from @CenterTBI #ICU data by probabilistic time-series clustering
𝗧𝗲𝗺𝗽𝗼𝗿𝗮𝗹 𝘃𝗮𝗿𝗶𝗮𝘁𝗶𝗼𝗻 of brain injury 𝗯𝗶𝗼𝗺𝗮𝗿𝗸𝗲𝗿𝘀 = missing link in describing the 𝗰𝗹𝗶𝗻𝗶𝗰𝗮𝗹 course
authors.elsevier.com/c/1i5LY…
@TheLancetNeuro
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CPPopt retweeted
8 Oct 2023
ICP is strongly confounded by therapeutic intensity level (TIL) after #TBI. Measuring TIL crucial to understand severity
Various TIL scores validated in @CenterTBI doi.org/10.1089/neu.2023.037…
@TBI_data_guy nails TIL representing 'refractory' ICP:
TILᵐᵉᵈ≥7.5
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CPPopt retweeted
12 Sep 2023
A solution to the age-old problem of where to zero the transducer in neurocritical care...
rdcu.be/dlTOs
doi.org/10.1007/s12028-023-0…
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CPPopt retweeted
21 Aug 2023
Does what happens in #ICU stay in ICU after #TBI?
Well done @TBI_data_guy for time-series #machinelearning model ingesting 𝑎𝑙𝑙
@CenterTBI data with minimal pre-processing looking at contribution of clinical course events to outcome in
@npjDigitalMed
nature.com/articles/s41746-0…
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CPPopt retweeted
22 Jul 2023
Precision medicine to improve outcome after traumatic brain injury: data-driven approaches to identify pathophysiological or pathobiological mechanisms to individualize treatments
🧠suggestions for #TBI phenotypes
🧠methodological considerations
#FOAMcc
🔓 rdcu.be/dhtsr
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CPPopt retweeted
19 Sep 2022
Machine learning and novel algorithmic techniques show great potential, but need to be applied and interpreted correctly
Right question right data right method
doi.org/10.1038/s41591-022-0…
@CC4AIM
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CPPopt retweeted
28 Jul 2022
Unsupervised clustering in @CenterTBI finds 6 stable endotypes of #TBI in the #ICU
⚠️Systemic metabolic stress important differentiating patients as well as traditional GCS classification
doi.org/10.1186/s13054-022-0…
rdcu.be/cSxc0
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CPPopt retweeted
6 Jul 2022
#TraumaticBrainInjury research often dichotomises outcomes. Here's how to handle ordinal outcomes from @shubhayu_neuro including a #machinelearning approach using 𝙖𝙡𝙡 the @CenterTBI features for best prediction
doi.org/10.1371/journal.pone…
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CPPopt retweeted
19 Mar 2022
Some 𝘷𝘦𝘳𝘺 important things to know about the challenges of large-scale observational data collection in #TBI from @CenterTBI
doi.org/10.1007/s12028-022-0…
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CPPopt retweeted
Primary analysis of @global_neuro Global Neurotrauma Outcomes Study #GNOS published tonight @TheLancetNeuro.
thelancet.com/journals/laneu…
Phenomenal collaboration of clinicians from 57 countries 🌍.
#WFNS2022 #globalneurosurgery #globalneurotrauma #TBI
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CPPopt retweeted
8 Jan 2022
Yes, and Cogitate study is one of the most read papers in 2021!!
7 Jan 2022
Check out the most read papers from Journal of Neurotrauma. liebertpub.com/action/showMo…
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Reduced physiological cross-talk associated with mortality after #TBI
Well done Giovanna, @BrainPhysics @DrSmielewski @erta_beqiri @pl219_Cambridge @AriErcole and all @CenterTBI collaborators
doi.org/10.1007/s12028-021-0…
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CPPopt retweeted
24 Aug 2021
First ever prospective randomised controlled trial to assess feasibility and safety of a 'digital biomarker' for individualised care of #TBI patients on #ICU
➡️ both feasible and safe
#COGITATE
doi.org/10.1089/neu.2021.019…
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We did it! First CPPopt feasibility and safety trial!
Results are here doi: 10.1089/neu.2021.0197
Is precision medicine in #TBI in #CriticalCare feasible? CPPopt as an individualised dynamic CPP target for protecting the brain.
Thanks #COGiTATE team for this work!
23 Aug 2021
The Autoregulation-Guided Cerebral Perfusion Pressure after Traumatic Brain Injury (COGITATE) results have been published!! @AriErcole @DrSmielewski @Menon_Cambridge @TasJeanette @iccvanderhorst @joseph_aotearoa @pja_hutch @erta_beqiri @GMeyfroidt
Link: lnkd.in/dfjp-WDH
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CPPopt retweeted
7 Aug 2021
Glasgow Coma Score & pupil reactivity=crucial #TBI outcome determinants but timepoints frequently missing in real-world data
Evaluation of methods for effective imputation by @CenterTBI...
... the answer depends on the question!
doi.org/10.1371/journal.pone…
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