Haven't been on here much, mainly due to recovering from longcovid and it being exhausting. Despite all that, v.pleased with our latest collaborative work (aptly) on rapid SARS-CoV-2 variant detection with ability to discriminate single nucleotide changes. medrxiv.org/content/10.1101/…
3/ The cross-School @cardiffuni Screening Service based in @CUBiosciences , led by Dr Tomasz Jurkowski and Prof Pete Kille - winner of the “Exceptional Enhancement of Staff Wellbeing” award
1/ Dr Tomasz Jurkowski - winner of the "Vice-Chancellor’s Award for Outstanding Contribution to the University" - for his "extraordinary action" in his central role establishing the university's #COVID19 testing service. This is the only award chosen by the Vice-C!
People seemed to quite like levitating droplets, so a couple more vids from @JinLi_AOR
First, Jin shows you can spin and reshape droplets, using this to break/reform lipid bilayers (DIBs) between internal cores, and to reconfigure the droplet network.
biorxiv.org/content/10.1101/…
We've a new pre-print "Building programmable multicompartment artificial cells incorporating remotely activated protein channels using microfluidics and acoustic levitation" up on @biorxivpreprint. Great effort by @JinLi_AOR on this work.
biorxiv.org/content/10.1101/…
As @DrMikeBooth's team point out in their recent review (frontiersin.org/articles/10.…) control of artificial cells is going to be vital for future applications. Here we address this by using ultrasonic & magnetic fields to selectively activate MscL channels in work with @phatmattbaker
Levitating artificial cells is kinda fun in itself, but @JinLi_AOR also shows how this can be used with microfluidics to reorganise, pattern and manipulate the internal structure and connectivity of artificial cells & also control function with selective activation/deactivation.
Building programmable multicompartment artificial cells incorporating remotely activated protein channels using microfluidics and acoustic levitation biorxiv.org/cgi/content/shor…#bioRxiv
Haven't been on here much, mainly due to recovering from longcovid and it being exhausting. Despite all that, v.pleased with our latest collaborative work (aptly) on rapid SARS-CoV-2 variant detection with ability to discriminate single nucleotide changes. medrxiv.org/content/10.1101/…
We applied to wastewater samples as well. In Cardiff, Swansea & Newport. We see the change in dominance from wildtype to Alpha to Delta - perhaps not surprising - but we also pick up the presence of Beta VoC in the community in a high background of Alpha. Useful for surveillance?
Can be readily adapted to any newly identified VOCs or other pathogens. Lots of hard work from Xinsheng and @tomek_criters and everyone really, but especially these two. Great project to be involved in. Have a read here (pre-print, not yet peer-reviewed) medrxiv.org/content/10.1101/…