This account is run by members of the Chaput Lab 🥼 Pioneering the next generation of diagnostic and therapeutic agents 🧬
Joined May 2021
- Tweets 83
- Following 173
- Followers 202
- Likes 330
31 Photos and videos
May 8
Happy belated birthday to our wonderful PI, Dr. Chaput, who the lab celebrated early this week! Cheers to another great year ahead 🥂
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Apr 23
We love our undergrads! Our very own Pranav Das (‘26) presented his crystallography research through UCI’s Undergraduate Excellence in Research program yesterday. Keep up the great work! ✨🧬
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Apr 20
Congratulations to our incredible Joy Lee on her successful advancement Tuesday! We’re so excited to keep watching you shine 💪🏻✨
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Mar 1
Pop the champagne! 🍾 Our very own Victoria successfully defended her thesis on the evolution and structural elucidation of TNA polymerases this week! Congrats, Dr. Maola-Gross—we couldn’t be prouder!! 🎉
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Feb 20
The @ChaputLab holds great opportunities for undergraduates at UCI to pursue research in structural biology. Check out this article highlighting one of our star students, Gracie Ko!
pharmsci.uci.edu/2026/02/17/…
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Jan 31
Our matching XNA scientists were spotted presenting their research today during the PharmSci PhD prospective student week! ☀️
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Jan 29
Newly published in NAR: the @ChaputLab has demonstrated TNA’s utility in gene silencing by enhancing the cellular activity and stability of RNA-targeting DNAzymes. A big step forward towards the future of oligonucleotide therapeutics! ✨🔬 academic.oup.com/nar/article…
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Jan 14
How does evolution reshape enzyme activity? In a recent Nature Communications paper, members of the @ChaputLab are helping answer this question through new insight on the forces responsible for shaping enzyme function. Check it out! nature.com/articles/s41467-0…
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Jan 13
Our incredible Erica Lee was named one of UCI’s annual Pharmaron Fellows! Congrats to Erica on her hard work and success throughout graduate school!
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Jan 12
Major kudos to members of the @ChaputLab for their recent publication in Nature Chemical Biology, pushing the boundaries of enzyme evolution with a robust and highly processive RNA polymerase! Looking forward to more exciting campaigns in 2026 🎊🧬
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14 Jul 2025
Inspired by nature, chemists have spent the last 50 years systematically designing and synthesizing a vast array of sugar modified nucleic acids, so-called xenonucleic acids (XNAs). Check out this NAR review on the XNA alphabet! academic.oup.com/nar/article…
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19 Jun 2025
Big congratulations to Clark, who recently defended his Masters thesis, titled: “Development of Improved Scalable Synthesis of Nucleoside Triphosphates.”
Well done, Clark! 🎓⭐️
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18 Jun 2025
Congrats to our PhD student @MaolaVictoria, recipient of UCI pharmaceutical science’s Henry Wood Elliot Award! 👏
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Chaput Lab retweeted
Big congrats to Dr. John Chaput, ranked #24 in the world in Synthetic Biology by @ScholarGPS! This Top Scholar honor puts him in the top 0.5% of researchers worldwide based on impact, citations & productivity. @ChaputLab
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2 Apr 2025
John Chaput and Mano Manoharan at the Nucleic Acid Therapies meeting, hosted at Cold Spring Harbor Laboratory! @CSHL
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28 Feb 2025
Congrats to our very own Dr. Esau Medina on a successful PhD defense! 🎓🧬
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Chaput Lab retweeted
Our PhD students showcased their groundbreaking research at our PhD Campus Visit Poster Session! 📊✨ Prospective students had the opportunity to connect with current PhD candidates and faculty members, gaining insights into our PhD in Pharmacological Sciences program at UCI.
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17 Jan 2025
Congrats to Esau Medina for his work on measuring XNA polymerase fidelity in hydrogels -- just accepted into NAR! Starting 2025 off strong!
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17 Jan 2025
Jan 2025: The lab officially welcomes our newest graduate student, Alex Horton! ⭐️🧬
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17 Jan 2025
Congrats to our recent graduate, Dr. Daniel Schuder, for his article acceptance into ACS Syn Bio (2024)! Check it out here! pubs.acs.org/doi/10.1021/acs…
Using a REVEALR-Based Diagnostic Panel for Rapid Detection of Acute Respiratory Infections
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