A reintroduction feels appropriate.
I have a degree in nutrition, medicine, am internal-medicine certified. My practice focuses on dysregulated metabolism and the treatment of obesity and other weight-related comorbidities.
My goal is to help you understand what we now know.
Last week my cousin was playing lacrosse. Today, we’re glad he can walk.
For a very tense 12 hours, we thought we might lose him.
During my hardest days in residency, I would be grateful to not be the patients in the beds. Hospitals help dose perspective and build gratitude.
Low T is not to be ignored or skirted around. 85% of the time, it’s a sign of underlying disease that is driving the low T.
Whether you pursue TRT or not, at least figure out WHY it is low.
A colleague, Joseph Zucchi, PA-C, MPAS shared the following on LinkedIn. It is an extraordinary infographic. With his permission, I am sharing the file here for others.
Eating less, not more, was shown to decrease the aging pace in this multi-center trial. These were in normal weight to moderately overweight subjects (BMI 22-27.9).
I’d be curious how aging is slowed in those with excess weight.
Look AHEAD: ~8% weight loss via lifestyle intervention → no CV benefit.
SELECT: ~9% weight loss via semaglutide → 20% reduction in MACE. Same weight lost, different outcome. The mechanism matters.
There were LOTS of benefits with wt loss. Just not decreased heart events 😔
Losing weight makes you hungrier. That’s not weakness. That’s leptin.
When fat cells shrink → leptin drops → your brain screams “EAT.”
The body defends its fat stores harder than you can white-knuckle a diet.
This is biology. Not willpower.
When we stop exercising and our diet lapses, weight is regained.
When we stop our cholesterol medications, cholesterol rises.
When we stop blood pressure (BP) meds, BP climbs.
When we stop contraceptives, fertility increases.
When we stop GLP1 medications, weight rises.
Here are some of the highlights on Retatrutide.
1️⃣ Binds 3 sites instead of 1 or 2
2️⃣ Weight loss approaches surgical outcomes
3️⃣ Similar side effect profile as semaglutide & tirzepatide
4️⃣ Side effects were dose dependent
Still not available, but promising so far.
Retatrutide is coming!
1️⃣It treats obesity (up to 22% wt reduction).
2️⃣Reduces osteoarthritis symptoms.
3️⃣Alleviates metabolic disease burden (eg, insulin resistance).
Side effects? Similar to our current GLP-1 agents.
This will change lives. #obesitymedicine
My last streak was more than two years long; hope to surpass it here. Thanks language learning platforms for making the world warmer, more inviting, and familiar. Learning another’s language tears down our perceived barriers! Muchísima gracias por todo @duolingo!