Our small green planet
Joined February 2018
- Tweets 25
- Following 41
- Followers 98
- Likes 27
1 Photos and videos
Dmitriy M Chudakov retweeted
Jan 6
N.B. VDJdb is up and running after a planned server upgrade, it can be now accessed at vdjdb.com, the old vdjdb.cdr3.net URL redirects there and should be considered obsolete. If you are using VDJdb web API please update accordingly.
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Dmitriy M Chudakov retweeted
24 Sep 2024
First manuscript from my group! š¢š¢š¢š¢ @StJudeResearch
23 Sep 2024
TCR repertoire dream: decoding immune status by sequencing TCRs. Problems: 1) Need paired TCRab chains 2) Interesting T cell clones are often VERY small. Our solution: TIRTL-seq š¢Deep, quantitative, & affordable paired TCR repertoire sequencing. š§µ biorxiv.org/content/10.1101/ā¦ (1/11)
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11 Jul 2024
Structure-based prediction of T cell receptor recognition of unseen epitopes using TCRen. Yes, it works: pubmed.ncbi.nlm.nih.gov/3898ā¦
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13 Apr 2024
And one more manuscript from our team, also focussed on Treg. Purely repertoire-based as we like)) Beautiful (!) data from Prof. Rudensky. Long work, short read. pubmed.ncbi.nlm.nih.gov/3859ā¦
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12 Apr 2024
Happy to report our development for scRNA-Seq analysis. Employs splicing information at the level of clustering and dimensionality reduction. Readily revealed beautiful aspects of Treg and Th1/CD4 cytotoxic biology. Try! biorxiv.org/content/10.1101/ā¦
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Dmitriy M Chudakov retweeted
24 Oct 2023
Targeted depletion of TRBV9 T cells induces remission in a single ankylosing spondylitis patient, with significant improvements in functional and mobility metrics #Immunotherapy #AnkylosingSpondylitis nature.com/articles/s41591-0ā¦
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24 Oct 2023
We started this work ~15 years ago. Now it is on the 2nd phase clinical trial. With all the circumstances, things evolve towards new generation immunotherapies, to make life happier on our small fragile planet.
24 Oct 2023
Targeted depletion of TRBV9 T cells induces remission in a single ankylosing spondylitis patient, with significant improvements in functional and mobility metrics #Immunotherapy #AnkylosingSpondylitis nature.com/articles/s41591-0ā¦
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5 Mar 2021
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Dmitriy M Chudakov retweeted
10 Feb 2021
Spectacular finding from Dmitryi Chudakov group (time to get a Twitter handle!) @CEITEC_Brno. Blind moles are special, they #live #long and prosper, now we know, at least in part, why. It goes down to the organisation of their adaptive #immune #system. š
8 Feb 2021
Izraelson et al. @CEITEC_Brno, @immunology_s reveal that the adaptive immune system of the long-lived blind mole rat is organized differently over its lifespan from other rodents. Read it here: nature.com/articles/s43587-0ā¦
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19 May 2020
Great Misha's work
19 May 2020
Our collaborative project (@pogorely, @elisarosix, @BensoudaMeriem, @an_franke, @ChudakovM and others) about longitudinal #TCR repertoire sequencing after #SARSCoV2 infection is now also on biorxiv. biorxiv.org/content/10.1101/ā¦
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29 Jan 2020
nature.com/articles/s41590-0ā¦
Admiration, envy, hope, inspiration ... altogether. And love for Andrew Sewell and his way of thinking. Ultimately - inspiration.
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29 Jan 2020
nature.com/articles/s41577-0ā¦
Yet many things unclear, but was a great pleasure to dig.
SupplTable1 tries to summarize clinically relevant things, some controverisal. Great work by George Sharonov.
Intersting what people say on IgG1/IgG3 difference hypothesized on Fig. 3.
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Dmitriy M Chudakov retweeted
5 Nov 2019
TCGA RNA-Seq analysis reveals strong association between Tumor-infiltrating B-cell antibody isotypes and survival in lung adenocarcinoma carrying specific driver mutations.
jitc.biomedcentral.com/articā¦
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28 Oct 2019
Comprehensive analysis of antiviral adaptive immunity formation and reactivation down to single-cell level disq.us/t/3j7jxy4
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Dmitriy M Chudakov retweeted
14 Feb 2018
Our latest study on immune responses to the flu vaccine and B cell memory in human tissues is out today and featured on the cover of @ScienceTM!
@TheDohertyInst @UniMelbMDHS stm.sciencemag.org/content/1ā¦
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Dmitriy M Chudakov retweeted
27 Feb 2018
CD8 T cells with characteristic T cell receptor beta motif are detected in blood and expanded in synovial fluid of ankylosing spondylitis patients academic.oup.com/rheumatologā¦
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Dmitriy M Chudakov retweeted
3 Mar 2018
New from Andrew Sewell lab: "PeptideāMHC Class I Tetramers Can Fail To Detect Relevant Functional T Cell Clonotypes and Underestimate Antigen-Reactive T Cell Populations" jimmunol.org/content/early/2ā¦ @J_Immunol
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Dmitriy M Chudakov retweeted
4 Mar 2018
Story of Alexander (Sasha) Rudenksy, recipient of 2018 #VilcekPrize in Biomedical #Science, discoverer of regulatory T cells #FOXP3 #Tregs youtu.be/SMWQMXKDDVM @UW @HHMINEWS @sloan_kettering @Ludwig_Cancer @UWalum #Proudimmigrant #UWalmamater #immunology
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