Inflammaging and Sarcopenia as Interconnected Hallmarks of Aging: Integrative Roles of Bioactive Compounds and Lifestyle Interventions ▶️ Age-related functional decline is increasingly linked to chronic low-grade inflammation (inflammaging) & sarcopenia, two interconnected processes contributing to frailty, metabolic dysregulation, & impaired physical function. ✅️ Natural bioactive compounds & lifestyle-based interventions represent promising approaches for targeting biological processes implicated in inflammaging & sarcopenia. ✅️ This review highlights the importance of adaptive redox regulation, metabolic resilience, & evidence-based lifestyle strategies in healthy aging. mdpi.com/2072-6643/18/12/192… @HealthyFellow @DHPSP Conceptual schematic framework illustrating hypothesized and partially evidence-supported interactions among lifestyle interventions, bioactive compounds, molecular signaling pathways, & functional outcomes in healthy aging. The figure is intended for conceptual interpretation & does not imply direct causal relationships for all depicted interactions.

Recent sunlight evidence points to possible systemic benefits, but the case is mostly observational and must be weighed against established UV skin-cancer risk. 🧵 1/7

AI generated a new green fluorescent protein unlike any known natural one.

The Gut–Lung Microbiome Crosstalk and Pulmonary Disease ✅️ The purpose of this review is to describe the important roles that the gut microbiota play in the pathogenesis and potential therapies of common pulmonary diseases. ▶️ Gut microbiota dysbiosis directly affects immune responses, altering disease severity in asthma, chronic obstructive pulmonary disease, cystic fibrosis, & lung infections such as pneumonia & COVID-19. ▶️ The gut microbiome plays a significant part in lung health & disease. ⚠️ Diet, tobacco smoking & electronic cigarette vaping all impact both the gut & lung microbiomes. mdpi.com/2218-273X/16/6/833 @HealthyFellow

Intermittent fasting shows mostly modest benefits; the clearest gains are versus usual eating, not an across-the-board edge over daily calorie restriction. 🧵 1/7

“Non-coeliac gluten sensitivity.” Published October 22, 2025, The Lancet doi.org/10.1016/S0140-6736(2…

A wrinkle cream making skin look younger isn't surprising. A topical serum making skin appear biologically younger is. 🔗link.springer.com/article/10… #antiaging

"Efficacy of vitamin D supplementation on glycaemic control in type 2 diabetes: An updated systematic review and meta-analysis of randomized controlled trials." Diabetes Obes Metab. 2024;26(12):5713-5726. dom-pubs.onlinelibrary.wiley…

Expecting gluten worsened symptoms more clearly than eating gluten alone in self-reported non-celiac gluten sensitivity. 🧵 5/7

Gluten can clearly harm people with celiac disease; in self-reported non-celiac sensitivity, many symptoms appear tied to wheat carbohydrates, expectations, or both. 🧵 1/7

Blood isn’t just carrying oxygen—it may be carrying your aging rate. 🔗nature.com/articles/s12276-0… #Aging #Longevity #Science #Biology

Brain Aging and the Pursuit of Longevity: Biological Mechanisms and Clinical Implications aginganddisease.org/EN/10.14…

Background TV was linked to poorer cognitive outcomes in young children.

"Standard" vitamin B12 ranges may be still too low, leaving older adults vulnerable to cognitive decline.

Bees might help fight cancer. 🐝 Scientists are studying melittin — a bee venom compound that can target tumor cells. Nature is smarter than we think. #CancerResearch #BeeVenom pmc.ncbi.nlm.nih.gov/article…

FDA Approves First Treatment for Chronic Hepatitis Delta Virus (HDV) Infection

Medical evidence can take about 17 years to change everyday clinical practice.

Across recent evidence, GLP-1 receptor agonists look like multi-organ metabolic therapies—not just glucose drugs—with real benefits and real safety and durability trade-offs. 🧵 1/7

Catch-up sleep after sleep restriction was linked to lower mortality.

Preschool ultra-processed food intake was linked to worse behavioral symptoms.