The Drug-Gene Interaction Database (DGIdb) is an open access, open source database that provides information on drug-gene interactions and gene druggability.

Joined October 2017
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Pinned Tweet
21 Sep 2020
Our latest major update is now officially live and described in our preprint!
Integration of the Drug-Gene Interaction Database (DGIdb) with open crowdsource efforts biorxiv.org/cgi/content/shor… #bioRxiv
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5 Dec 2025
Help the DGIdb development team understand how we can better promote hypothesis generation and interaction data sets for the biomedical and clinical research community. Take 5 minutes to share how you use DGIdb and what we can improve for your research: forms.gle/ohrk49dmHMPXzY1K8
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11 Nov 2025
DGIdb is currently planning new feature sets for our next development cycle! Features under consideration include the expansion of regulatory and pathways datasets, and more avenues for community engagement. Provide your feedback here: forms.gle/ohrk49dmHMPXzY1K8
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Elaine Mardis: More shoutouts to @treehousecancer and @DGI_db for interpretation of RNAseq data and identification of potentially druggable targets.
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DGIdb retweeted
The new Drug-Gene Interaction Database @DGIdb is live! Integration with crowd-sourced curation and data in network format available via @NDExProject : bit.ly/3kCjGHT Congrats to the whole team! @obigriffith @malachigriffith @HandlerWagner @DGI_db #nciitcr
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DGIdb retweeted
Major update just released: Integration of the Drug-Gene Interaction Database (@DGI_db v4.0) with open crowdsource efforts. Includes new/updated sources, improved drug normalization, query scores, @NDExProject integration, and more! biorxiv.org/content/10.1101/…
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5 Aug 2020
Shoutout from Elaine Mardis's keynote for the @CG_Consortium annual meeting! It's always exciting to see how our database is being used by others!
Replying to @CG_Consortium
Elaine Mardis: More shoutouts to @treehousecancer and @DGI_db for interpretation of RNAseq data and identification of potentially druggable targets.
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DGIdb retweeted
6 Sep 2019
Following the update of OmniPath we present our new annotations dataset 🥳 omnipathdb.org/annotations?p… Characterize a #protein using data from 36 resources! @HumanProteome @DGI_db @DisGeNET #MatrisomeDB #systemsbiology #omics @sysbiomed
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DGIdb retweeted
Replying to @DGI_db
@DGI_db (dgidb.org/) team is embarking on a major update (v4). If your favorite source of drug-gene interactions or druggable gene categories is missing, now would be a good time to let us know! Feature requests welcome, but major UI refactoring is slated for v5. :)

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DGIdb retweeted
Funding bill gives $3 billion boost for NIH medical research thehill.com/policy/healthcar…

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DGIdb retweeted
Latest review paper with Fei Wang just came out: Everything you need to know about drug knowledge bases and their applications in biomedical informatics research academic.oup.com/bib/advance…
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DGIdb retweeted
24 Oct 2017
.@UCSC Haussler Lab's Lauren Sanders shares her work combining @treehousecancer @PNOC_kids @DGI_db for #DIPG research @CI4CC #ci4cc2017
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DGIdb retweeted
We just got our v3.0 preprint out the door, manuscript in review. #DGIdb 3 is bigger, better, faster! dgidb.org x.com/biorxiv_bioinfo/status…

DGIdb 3.0: a redesign and expansion of the drug-gene interaction database biorxiv.org/cgi/content/shor… #biorxiv_bioinfo
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