Cancer Biologist @fredhutch

Joined February 2019
29 Photos and videos
Pinned Tweet
📣The MacPherson lab @fredhutch is hiring a postdoc to study the biology of small cell lung cancer. We employ in vivo models, genetic screens and genomic approaches to understand therapeutically target subsets of SCLC. $78K salary ⬆️ to >$90K after 2 yrs careers-fhcrc.icims.com/jobs…

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DavidMacPherson retweeted
22 Sep 2025
The Division of Human Biology @fredhutch is recruiting for a lab-based scientist at the Assistant or Associate Professor level. Come join a dynamic research community committed to pushing the boundaries of discovery in cancer biology. apply.interfolio.com/174007
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Thanks for highlighting our efforts to use in vivo CRISPR screens to identify drivers of resistance to chemotherapy in small cell lung cancer
In work published in Science Advances, researchers in the @DMacPhersonLab used #CRISPRCas9 on #SCLC tumor cells to better model how tumors that initially respond to chemotherapy become resistant. bit.ly/4krzUTn
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Our collaborative study with @GavinHa @fredhutch is out in @ScienceAdvances. Led by Joe Hiatt and Anna Lisa Doebley, we developed a liquid biopsy approach, SCLCpheno-seq, to classify SCLC subsets and distinguish from NSCLC based on analyses of ctDNA 1/X science.org/doi/10.1126/scia…
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Our fragmentomics approach complements other emerging strategies towards SCLC liquid biopsy phenotyping such as DNA methylation analyses and ChIPseq approaches. We advocate for broad application of different phenotyping approaches to patient samples 13/X.

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This work was possible only because of the contributions of our collaborators – Anish Thomas, @charlesrudin, Keith Eaton, McGarry Houghton, Caroline Dive, as well as SCLC patients and funding from NCI and @KuniFoundation 14/14
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DavidMacPherson retweeted
17 Feb 2023
We have an open joint-postdoc position with @DMacPhersonLab to work on new computational approaches for studying #lungcancer using #liquidbiopsy. If you're interested in cancer genomics, LBx, AI or #PrecisionOncology, pls apply! careers-fhcrc.icims.com/jobs…

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DavidMacPherson retweeted
I’m counting down the sleeps to @IASLC #SCLC23! Was thrilled to help organise this meeting together with @AlvaroQuintanal @DMacPhersonLab the twitter-less Kathryn Simpson & @charlesrudin. Don’t hesitate - register now! 👇
13 Feb 2023
Join us for #SCLC23! A meeting focused on preclinical/clinical advances in #SCLC research, including basic research on oncogenesis & biology of disease, preclinical therapeutic research & highlights of ongoing clinical translation. Register Now! bit.ly/SCLC23 #LCSM
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DavidMacPherson retweeted
Looking forward to @IASLC #SCLC23! So much fun to help organise this meeting together with superstars @Sutherland_Lab, @DMacPhersonLab, Kathryn Simpson and @charlesrudin. So many amazing talks with the latest advances in #SCLC. Limited spots! - register now! 👇
13 Feb 2023
Join us for #SCLC23! A meeting focused on preclinical/clinical advances in #SCLC research, including basic research on oncogenesis & biology of disease, preclinical therapeutic research & highlights of ongoing clinical translation. Register Now! bit.ly/SCLC23 #LCSM
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