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GenomeWeb Daily Scan @DailyScan

GenomeWeb blog covering editors' picks of what's worth reading on the Web.

Joined March 2009
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The new algorithm, described in this week's @PNASNews, can use ancient DNA to track the mobility of human populations in the past bit.ly/3ZdWkfW
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Researchers unravel the genetic mechanisms of fingerprint formation, reports @TheScientistLLC bit.ly/3kiYrk8
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A Las Vegas-based team examines in @JAMANetworkOpen the effect of visitors and tourists on wastewater-based surveillance of SARS-CoV-2 bit.ly/3It2ORA

Visitors May Affect Utility of Wastewater Analysis for COVID-19 Surveillance, Study Finds

A Las Vegas-based team examines in JAMA Network Open the effect of visitors and tourists on wastewater-based surveillance of SARS-CoV-2.

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Amidst its ongoing war with Ukraine, Russia has increased scientific collaborations with India and China, @Nature finds go.nature.com/3ZnIRm9
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An analysis in @CurrentBiology of ancient Yersinia pestis shows that the plague-causing bacterium was introduced in waves into medieval Denmark bit.ly/3XZI5uf
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Moderna shells out $400 million to pay the NIH for a government funded technique it used in its COVID-19 vaccine shot, reports @nytimes nyti.ms/3ZnggNL

After Long Delay, Moderna Pays N.I.H. for Covid Vaccine Technique (Published 2023)

Moderna has paid $400 million to the government for a chemical technique key to its vaccine. But the parties are still locked in a high-stakes dispute over a different patent.

nytimes.com
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. @Nature feature explores the state of research linking the brain to immune function, inflammation, and conditions ranging from heart disease to autoimmune conditions or cancer recovery go.nature.com/3IpQrpc
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Researchers use single-nucleotide sequencing and mass spec to map alkylation-derived DNA adducts in a lung cancer cell line exposed to benzo(a)pyrene in @ACSCentSci bit.ly/3Zg0oMH

DNA Damage Map Reveals Mutational Signature Stemming From Carcinogenic Compound

Researchers use single-nucleotide sequencing and mass spec to map alkylation-derived DNA adducts in a lung cancer cell line exposed to benzo(a)pyrene in ACS Central Science.

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Stanford University biochemist Paul Berg, a recombinant DNA pioneer and Nobel Prize winner in Chemistry, is remembered in @nytimes nyti.ms/3Imno60

Paul Berg, Nobel-Winning Pioneer of Genetic Engineering, Is Dead at 96 (Published 2023)

In 1971, he transferred material from one organism to another, creating the first recombinant DNA, or rDNA. He later helped lead a historic effort to write protocols for genetic research.

nytimes.com
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Researchers in @alzassociation journal linked obesity-related measurements such as body mass index and waist-to-hip ratio to increased or diminished expression of 21 Alzheimer's-associated genes bit.ly/41ngoyG

Framingham Heart Data Suggests Alzheimer's Disease-Related Gene Expression Influenced by Obesity

Researchers in Alzheimer's & Dementia linked obesity-related measurements such as body mass index and waist-to-hip ratio to increased or diminished expression of 21 Alzheimer's-associated genes.

genomeweb.com
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. @ScienceMagazine reports on a research team using induced pluripotent stem cells from adult bats to understand how bat species dodge diseases associated with the many viruses they carry bit.ly/41h8BlR

How do bats live with so many viruses? New bat stem cells hint at an answer

Research team hits on formula to create stem cells from tissue of adult

science.org
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Researchers develop, validate, and test a haplotype-based artificial intelligence model for identifying SARS-CoV-2 variants, mutations, and variant mixtures in @JAMANetworkOpen bit.ly/3EvVnrt
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A particularly deadly and dangerous version of monkeypox, or mpox, has been found in immunosuppressed individuals with advanced HIV, @guardian notes, prompting calls for increased testing bit.ly/3xMFOIa
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. @voxdotcom looks at pandemic-related learning loss, children's mental health, and what comes next for children and teens who fell behind when schooling moved online bit.ly/3YRrZUG
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Using nanopore sequencing, researchers profile the germline structural variant breakpoints, unbalanced SVs, and allelic heterogeneity in several breast cancer risk genes in the @ejhg_journal bit.ly/3ImeWnj

Breast Cancer Structural Variant Features Unearthed With Long-Read Sequencing

Using nanopore sequencing, researchers profile the germline structural variant breakpoints, unbalanced SVs, and allelic heterogeneity in several breast cancer risk genes in the European Journal of...

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. @NPR's Goats and Soda profiles a nurse from rural Guatemala who is part of a local clinic and laboratory focused on active surveillance for emerging and established infectious diseases n.pr/3ZfhJWp

A kid in Guatemala had a dream. Today she's a disease detective

Neudy Rojop made a girlhood pledge. When family members fell ill, she says she decided to become a nurse "so I could change my community for good."

npr.org
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With data from hundreds of prior studies, researchers explore genetic ties between neurodevelopmental conditions and with disruptive, impulse control and conduct disorders in @NatureHumBehav bit.ly/3Z6hPzq

Meta-Analysis Points to Neurodevelopmental Disorder Heritability, Genetic Overlap

With data from hundreds of prior studies, researchers explore genetic ties between neurodevelopmental conditions and with disruptive, impulse control and conduct disorders in Nature Human Behaviour.

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. @guardian says University of Oxford mathematical biology professor Dame Angela McLean will become UK's first female chief scientific advisor, starting in April bit.ly/3ErYgcX

Dame Angela McLean to be UK’s first female chief scientific adviser

Professor of mathematical biology to succeed Sir Patrick Vallance after advising MoD and working with Sage during pandemic

theguardian.com
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Researchers in @PNASNews find two repeat-rich proteins that are sometimes expressed from the mammalian telomeric RNA TERRA, particularly when telomere problems are present bit.ly/3II7WCx

Repeat Protein Products Production Possible From Telomeric RNA, Study Suggests

Researchers in PNAS find two repeat-rich proteins that are sometimes expressed from the mammalian telomeric RNA TERRA, particularly when telomere problems are present.

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A previously HIV-positive patient treated with HIV-resistant donor stem cells has been free of the disease since 2018, without the need for antiretroviral therapy, @Nature reports go.nature.com/41ke5MO

Third patient free of HIV after receiving virus-resistant cells

Nature - But the risks associated with the procedure mean it is unlikely to be used widely in its current form.

nature.com
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