Cilia, centrioles, signaling & cell cycle - Yale University - Molecular, Cellular & Developmental Biology
Joined June 2017
- Tweets 189
- Following 874
- Followers 1,376
- Likes 1,038
13 Photos and videos
David Breslow lab retweeted
May 7
Please come join me in Washington, DC August 2-6th for the FASEB SRC on Cilia and Centrosomes meeting! Over 40 talks will be selected from abstracts. We are also excited to launch our first North American Ciliopathy Summit, held at the same venue on Aug 2. events.faseb.org/event/cilia…
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David Breslow lab retweeted
Imaging-based CRISPR genome screening allows effects of cell-regulating molecules & modifications to be revealed in live & fixed cells – applied here to frog embryo cilia
📹 Jingbo Sun et al @DavidBreslowLab @Yale in @Dev_Cell
➡️ bpod.org.uk/archive/2026/1/2…
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21 Nov 2025
Ever wanted to do a genome-scale CRISPR screen for a microscopy-based phenotype? Pooled CRISPR screens are amazing, but hard to combine with microscopy... Excited to share a technology platform for such imaging screens and applications to primary cilia... cell.com/developmental-cell/…
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21 Nov 2025
SMIM27/TZMP1 KO cells don't form cilia. TZMP1 localizes to the transition and by IP/MS is part of the MKS complex at the transition zone. With Mustafa Khokha, we find conserved roles in ciliary function in Xenopus embryos.
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21 Nov 2025
Lots of potential for future ciliary (and non-ciliary) screening applications. Great work by all authors, especially postdoc Jingbo Sun. And great collaboration with the Khokha lab!
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David Breslow lab retweeted
20 Nov 2025
Online now: A microscopy-based CRISPR screening platform enables organellar functional genomics and illuminates ciliary biology dlvr.it/TPNHyB
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30 Oct 2025
Excited to share our latest work on a new cilia disassembly pathway & a link between this pathway and the neurological disorder focal cortical dysplasia: science.org/doi/10.1126/scia…
Summary: From a genome-wide CRISPRa GOF screen to identify negative regulators of ciliary signaling...
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30 Oct 2025
3) it is noteworthy that a GOF CRISPRa screen was able to uncover a connection to a disorder caused by somatic activating mutations; possibly CRISPRa screening may be broadly useful for studying such diseases caused by somatic mutations ...
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30 Oct 2025
Great work by all authors, especially first Breslow lab grad student Shane Elliott. And thanks also to excellent collaborations at Yale with labs of Angelique Bordey and Tony Koleske
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David Breslow lab retweeted
9 Sep 2025
Calling all biologists! 📢
Is your research at the cutting edge of synthetic biology, genomics or AI?
Apply to join our team of world-class scholars!🔬🦠
Tenure-track Assistant Professor
Anticipated Start Date: July 1, 2026
#hiring #genomics #biology
apply.interfolio.com/172428
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David Breslow lab retweeted
8 Feb 2025
NIH indirect costs fund the backbone of research: maintaining labs, ensuring safety, and supporting admin work. These are essential for groundbreaking discoveries. Drastic cuts to NIH indirect rates are detrimental to academic biomedical research.
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Proud to share our work by a fantastic team, spear-headed by PhD student @Kainerox with major contributions by #xenopus expert @RosiFeistel.
We developed an improved iAPEX-based #ProximityLabeling method for #massspec based subcellular #proteomics.
biorxiv.org/content/10.1101/…
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