Translational tumor immunologist, breast cancer pathologist, passionate about cancer immunotherapy

Joined July 2023
6 Photos and videos
This account is not active. You can find me @sandrademarialab.bsky.social
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Join the SITC Run Club for the 2025 AACR Runners for Research 5K Run/Walk in support of Cancer Research! do.nr/49dr11dl via @DonorDrive @gulleyj1 @JennGuerriero

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Happy to be recognized by @Clarivate as a 2024 Highly Cited Researcher who has demonstrated significant influence in their field! #HighlyCited2024 clarivate.com/highly-cited-r…
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Sandra Demaria retweeted
➡️Join us October 11th at the JBL Symposium to hear from leaders in radiation oncology and AI in medicine including @HugoAerts (@harvardmed) @DrRebeccaHowel1 (@MDAndersonNews) @DemariaLab_WCM (@WeillCornell) & @HenningWillers (@MGHCancerCenter)! Info: hsph.harvard.edu/jbl-center/…
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September @sitcancer #JITC Reading List by Section Editor Sandra Demaria @DemariaLab_WCM @WeillCornell selection #4: FcγRIIB Is an Immune Checkpoint Limiting the Activity of Treg-Targeting Antibodies in the Tumor Microenvironment by @RockefellerUniv and @ChilesResearch bit.ly/3MRuLoU
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5 Oct 2024
Jalal Ahmed presented exciting insights into enhancing CAR T cell therapy in solid tumors in the last talk of this "Novel Approaches" session. His talk focused on how radiotherapy (RT) can improve the effectiveness of CAR T cells in solid tumors.
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5 Oct 2024
🗺 To finish this second day of the Immunorad conference, Brian D. Brown presented exciting research on how tumor microenvironment (TME) composition impacts immunotherapy (IO) success.
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5 Oct 2024
Dr. Sierra McDonald presented complementary findings from the P-RAD clinical trial and a genetically engineered TNBC mouse model:
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4 Oct 2024
⭐ Exciting takeaways from Anguraj Sadanandam, Ph.D.'s talk on AI and single-cell data analysis. He began by discussing the challenges of data-driven algorithms, emphasizing that cancer evolution is multifactorial and requires diverse data inputs.
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4 Oct 2024
Timothy Chan kicked off the "Cancer Immunogenomics and Radiation Therapy" session with a detailed talk emphasizing the need for biomarker identification to improve the efficacy of RT/IO combinations.
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4 Oct 2024
⌚️To finish this session, Sean Pitroda presented extensive research on “Immunogenomic Responses to Combination SBRT and Immune Checkpoint Blockade in Metastatic NSCLC.” , from a recently published work originally from COSINR randomized phase I trial.
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4 Oct 2024
Exciting updates from Gaorav Gupta on the P-RAD trial—the first randomized study comparing aPD-1 alone vs. aPD-1 RT in early-stage, LN metastatic, TNBC, and high-risk HR-HER2- breast cancer:
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4 Oct 2024
Great insights from Dr. Kristina Young’s talk on targeting TGF-β in rectal cancer, showing that TGF-β directly impact CD8 T-cells anti-tumor efficacy
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4 Oct 2024
🌟 Exciting Insights from Alan Melcher's talk on T Cell Dynamics and Radiotherapy in Rectal Cancer! 🌟 During his presentation, Prof. Melcher highlighted how a strong immune response to radiotherapy mimics viral infection.
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4 Oct 2024
⭐️Kicking off the second day of ImunoRad, Anne-Gaëlle Goubet presented an exciting talk on leveraging Flash Radiotherapy for immune engagement and tumor control.
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3 Oct 2024
Dr. Ben Chetrit stressed the need for developing innate immune strategies, particularly targeting Notch4 to reverse macrophage-related immunosuppression.
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3 Oct 2024
"Radiation Therapy-Induced Modulation of the Tumor Immune Microenvironment" kicked off with insights from James Welsh on novel strategies to tackle checkpoint resistance.
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3 Oct 2024
📷 Gut-Immune Axis: Healthy gut microbiome dysbiosis can enhance the immune system's ability to fight cancer cells 📷Low-dose #radiation: When combined with specific gut bacteria, can boost the response to immunotherapy and may drive the #abscopal effect. Prospective study inc
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3 Oct 2024
Dr. @Laurence Zigvogel's introductory presentation shed light on the revolutionary potential of the #gut #microbiome in combating cancer. 📷 #Antibiotics: Disrupting the delicate balance of gut bacteria with antibiotics can hinder the effectiveness of immunotherapy.
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