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Developmental Interactions Lab @DevInteracts

Research on developmental interactions at Faculty of Veterinary Medicine, University of Helsinki, Finland

Joined December 2019
  • Tweets 55
  • Following 2
  • Followers 69
18 Photos and videos
Developmental Interactions Lab website: helsinki.fi/en/researchgroup…
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Talk about bacterial extracellular vesicles by @MikaelNiku at #MOVE2025. They are thought to mediate microbe-host interactions in the intestine and possibly beyond. We investigate the vesicle proteomes of the mammalian intestinal microbiota. 🧵
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5/ Researchers at @UniOulu reported bacterial extracellular vesicles in the human amniotic fluid. This suggests that they may also stimulate the early development of the immune system. doi.org/10.1186/s40168-023-0…

Maternal microbiota communicates with the fetus through microbiota-derived extracellular vesicles

Microbiome - Reports regarding the presence of bacteria in the fetal environment remain limited and controversial. Recently, extracellular vesicles secreted by the human gut microbiota have emerged...

link.springer.com
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6/ We are now studying the bacterial extracellular vesicle proteomes to learn more about their potential functions and to develop novel tools for targeted investigations. Stay tuned - preprint coming soon!
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Presenting our research on the effects of gestational antibiotics on offspring microbiota, immune system and growth, and on bacterial extracellular vesicle proteomes at @iuis_online #IUIS2025!
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Rose gave an excellent talk at the @BioCityTurku symposium "Unleashing the power of metabolism" #BCS2024!
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Developmental Interactions Lab retweeted
MetaStem @MetaStem_Center
30 Nov 2023
Welcome to the Metabolism seminar next week Friday Dec 8th 9-11am in Viikki. Exciting talks on #lipidomics in human disease by @samrip lab and maternal #microbiome #metabolites in development by @MikaelNiku lab. ☕️🍪at 8:30 @LifeSciHelsinki @FIMM_UH @HiLIFE_helsinki @BIOTECH_UH
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Exciting new research on prenatal host-microbe interactions from our colleagues in Oulu! x.com/MicrobiomeJ/status/172…

Microbiome @MicrobiomeJ
14 Nov 2023
Maternal microbiota communicates with the fetus through microbiota-derived extracellular vesicles dlvr.it/Synl7C
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Presenting our research at the meeting of the Finnish Society of Developmental Biology! Great event, great atmosphere.
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Press release on our latest research: maternal microbiota and microbial metabolites can modulate fetal development helsinki.fi/en/news/healthie…

Maternal microbiota can affect foetal development | University of Helsinki

In a Finnish study, significant differences in the gene activity of the foetal intestine, brain and placenta were identified, depending on the microbes in the mother’s body and the compounds produced...

helsinki.fi
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How does the maternal microbiota modulate fetal development? We compared fetal intestine, brain and placenta from germ-free and normal mice. We saw broad differences in gene expression, associated with known & novel microbial metabolites. Now @BMCBiology: doi.org/10.1186/s12915-023-0…

Impacts of maternal microbiota and microbial metabolites on fetal intestine, brain, and placenta

BMC Biology - The maternal microbiota modulates fetal development, but the mechanisms of these earliest host-microbe interactions are unclear. To investigate the developmental impacts of maternal...

link.springer.com
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Thanks for great work @laiske @ville_koistinen @KatiHanhineva @karkkainen_olli @antagomir & co! Ping @GanalVonarburg @Kathrynated @FinlayLab @ntorow @BrodinPetter @socmucimm
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Thanks also @FIMM_UH @AfektaTech @InfrafrontierEU @IGCiencia!
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