Together with Chun Kan Chen's and @slavicaPD groups we have recently optimized our RAPPL method for the isolation of ribosomes and ribosome fragments from biopsies (5-10mg), tissues (1-5mg) and small blood samples (100-500ul). Soon more on RAPPL Ribo-Seq... Images from ribosome isolation from 100ul of blood, RAPPL-RiboSeq reads and comparison of low expression genes with RAPPL RiboSeq on 250K cells with 10 million cells with classical method. Pending patent #63/694,196 (WU Ref No. 020910/US) nature.com/articles/s41467-0…

It is a great privilege to be named Mencoff Family RNA Research Professor of Molecular Biology, Cell Biology and Biochemistry at Brown University. I am grateful to Samuel M Mencoff and Mencoff Family, Brown University, Department of Molecular Biology, Cell Biology, and Biochemistry and Guiliani RNA Center at Brown for this honor. Djuranovic lab will soon celebrate their first year at Brown University.

Fresh out of the press today. Great colaboration with @slavicaPD and @Mak_Mitreva labs as well as multiple other ones involved in this project. nature.com/articles/s41467-0…

10 days of RNA science in Montreal. RNA Society Meeting and Codon Usage Meeting one after other.

Our polyA track and splicing story is out today. More on Zcrb1 and it's role in U12 splicing, cilia, centrosome and l coming soon from Stratman and Djuranovic labs. Loss of U11/U12 spliceosome gene ZCRB1 leads to aberrant ciliogenesis and WNT signaling life-science-alliance.org/co…

Excited to share the first paper from our new lab @UTSWMedCenter @UTSWScience ! 🎉 Now out in @NatureComms Mechanisms of human mitochondrial leaderless mRNA translation initiation nature.com/articles/s41467-0…

4 years after terrible loss (two -80C freezers and back-ups) of almost all of our collection of regular and mutant human, Drosophila, E. Coli and Plasmodium cells, and a big hustle with insurance we are going to publish first manuscript that was hindered by this loss. Additional 2 manuscripts are on the way as well. Lot of repeated experiments, use of additional resources and lot of lost nerves over the last 4 years that could have been avoided. This was a valuable collection of mutant cell lines as well as CRISPR/Cas9 engineered lines with endogenously tagged-RBPs, translation factors, ribosomal proteins and other proteins. More than 50% of engineered Plasmodium cells are still not recovered. My suggestion to everyone is to keep some of your most valuable cell lines and back-ups in your collaborators freezers or at least in different buildings or towns.

Our RAPPL international patent application has just been published. @slavicaPD

Visit from a friend and great colleague from Newcastle University. Sergey Melnikov will after snowy February in Providence talk tomorrow about hibernating ribosomes. Another talk at Brown RNA Center. #ribosomes #RNA

Together with Chun Kan Chen's and @slavicaPD groups we have recently optimized our RAPPL method for isolation of ribosomes and ribosome fragments from biopsies (5-10mg), tissues (1-5mg) and small blood samples (100-500ul). Soon more on RAPPL Ribo-Seq... Images from ribosome isolation from 100ul of blood, RAPPL-RiboSeq reads and comparison of low expression genes with RAPPL RiboSeq on 250K cells with 10 million cells with classical method . nature.com/articles/s41467-0…

@DjuranovicLab welcomes new postdoctoral fellow @SiddikAlom19 from OSU and @FredrickLabOSU More ribosome research to come soon.

A few months ago (Sep 30th of 2025) @uspto granted yet another one of my patents on how to modulate translation efficiency by changing first 5 codons/amino acids. The origin of this patent is the work from the lab that was published back in 2019 in Nature Communications. Soon we'll have more on this... nature.com/articles/s41467-0…

Great visit and lot of fun with Yury Polikanov this week at Brown RNA Center

Great collaboration with @CarpeRibosomam and @slavicaPD labs on using MPRAs to look into non-coding mutations. Approaches for identification of 5′ UTR mutations impacting translation and protein production from neurodevelopmental disorder genes: Cell Reports Methods cell.com/cell-reports-method…

It was great to be there. Looking forward to more such meetings!

On the way back from one week of great science, technology and therapeutic potentials of RNA in organization of @ImmaginaBiotech . Thanks for the great meeting to Max and the Immagina team. Looking forward to future collaborations. #RNA #tRNA #ribosome

We are hiring…position suitable for PhD student with interest in ribosomes, antibiotics and cryoEM… uni-hamburg.de/en/stellenang…