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Dog Genome Annotation Project @DogGenome

Improving the dog genome knowledge as a model for human health

Joined September 2018
  • Tweets 62
  • Following 41
  • Followers 65
13 Photos and videos
📈 Whether studying tissue enrichment, disease genes, or SNPs, our Shiny app provides powerful visualizations (scatter plots, heatmaps) to aid in data exploration and discovery. #genetics #dataexploration expression-atlas.doggenomean…
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💡 With this Expression Atlas tool, researchers can easily access, analyze, and visualize canine promoter and gene expression, accelerating the study of genetics and diseases. #genomics #bioinformatics #dogresearch expression-atlas.doggenomean…
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Doga In use: Smarter genome annotation with ANNEXA 🧬 Annotating the canine genome just got easier: ANNEXA long-read RNA-seq = next-gen precision. biorxiv.org/content/10.1101/…

Facilitating genome annotation using ANNEXA and long-read RNA sequencing

With the advent of complete genome assemblies, genome annotation has become essential for the functional interpretation of genomic data. Long-read RNA sequencing (LR-RNAseq) technologies have...

biorxiv.org
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Doga In use: Canine transcriptional architecture mapped 📊 From promoters to enhancer clusters—Pol II regulation across the dog genome just got a whole lot clearer.biorxiv.org/content/10.1101/…

Transcriptional architecture and Pol II regulation at promoters, enhancers, and enhancer clusters...

Domestic dog exhibits remarkable phenotypic diversity and provides versatile models for genomics, evolution, and complex traits. DNA sequences and stable RNAs have revealed regulatory regions in the...

biorxiv.org
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Doga In use: 🧠 Genetic mystery solved: The RSPO2 gene is associated with bilateral anterior amelia in Chihuahuas. Rare traits, now decoded.link.springer.com/epdf/10.10…
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Doga In use: Check out this paper Common variants in the CPT1A gene are now linked to cataracts in Northern dog breeds. A step forward in understanding inherited canine eye diseases.journals.plos.org/plosone/ar…

Common variants in the CPT1A gene are associated with cataracts in Northern breeds of domestic dog

Primary hereditary cataract affects many purebred domestic dog breeds and is a major cause of visual impairment in dogs. Cataracts are common in Northern breeds such as the Siberian Husky, Alaskan...

journals.plos.org
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🔄 Switch easily between robust and comprehensive datasets: the comprehensive dataset includes all promoter regions, while the robust dataset focuses on those replicated in at least three samples. #dataanalysis #genomics expression-atlas.doggenomean…
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🧠 The app lets you dive deep into behavior-associated SNPs, giving insight into how genetics impact dog behavior. Perfect for researchers studying canine genetics! #dogbehavior #genomics expression-atlas.doggenomean…
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🌍 We’ve incorporated SNP cluster data from dog lineage and behavior studies! Visualize overlapping expression in heatmaps and explore SNPs related to lineage and behavior. #SNP #dogbehavior expression-atlas.doggenomean…
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🧪 In the Disease-Associated Genes tab, search for genes and diseases from OMIA to visualize tissue expression linked to specific conditions, using scatter plots or heatmaps. #disease #genomics expression-atlas.doggenomean…
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🔑 You can refine results by selecting a robust dataset with higher thresholds for expression levels and replicability, ensuring more reliable data for your research. #dataquality #genomics expression-atlas.doggenomean…
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🧬 Our Tissue Enrichment Panels let users explore genes and promoters enriched in specific tissues. Just select a tissue or organ system to see a list of overexpressed genes. #genomics #bioinformatics expression-atlas.doggenomean…
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🔬 We’ve developed a user-friendly Shiny appto provide intuitive access to DoGA promoters and gene expression data. Now exploring canine gene expression and tissue enrichment is easier than ever! #genomics #bioinformatics expression-atlas.doggenomean…
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📊 The Expression Panel in our app allows users to view promoter expression across various organ systems and tissues. Find genes and promoters by name or by searching specific regions. #genetics #doggenomics expression-atlas.doggenomean…
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DoGA group meeting Jan 2025 in Helsinki. Analysis presentation and discussion for future publications.
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This year DoGA project achieved a milestone by our latest publication and addition to DoGA resources through DoGA expression atlas. We can’t wait to contribute to science in coming year. Happy new year from DoGA.
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🌟 The DoGA Atlas is revolutionizing our understanding of gene regulation in dogs and wolves, setting the stage for cutting-edge research into genetic diseases, behavioral traits, and more. #CanineGenomics #GeneRegulation #ResearchBreakthrough nature.com/articles/s41467-0…
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🐕💡The DoGA resource is a huge step forward for both veterinary & human medicine! It's helping scientists decode the complex genetics of dogs & wolves for breakthroughs in disease treatment & prevention. #GenomicMedicine #VeterinaryResearch #DogHealth nature.com/articles/s41467-0…

The DoGA consortium expression atlas of promoters and genes in 100 canine tissues

Nature Communications - The Dog Genome Annotation (DoGA) study is based on 5’ transcriptomics of 132 dog tissues. Here the authors identify over 100,000 promoters and provide an expression...

nature.com
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📚 The DoGA Atlas is now available! With interactive tools for gene expression and promoter data, it’ll accelerate studies on genetic diseases in both dogs & humans, making it a critical resource for scientists worldwide. nature.com/articles/s41467-0…

The DoGA consortium expression atlas of promoters and genes in 100 canine tissues

Nature Communications - The Dog Genome Annotation (DoGA) study is based on 5’ transcriptomics of 132 dog tissues. Here the authors identify over 100,000 promoters and provide an expression...

nature.com
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🌍 Global collaboration leads to a transformative genomic resource! Over 5,000 canine & wolf samples, cutting-edge RNA sequencing, and a new era of cross-species research for genetic disorders. 🚀 #DoGAConsortium #GeneticResearch #VeterinaryScience nature.com/articles/s41467-0…

The DoGA consortium expression atlas of promoters and genes in 100 canine tissues

Nature Communications - The Dog Genome Annotation (DoGA) study is based on 5’ transcriptomics of 132 dog tissues. Here the authors identify over 100,000 promoters and provide an expression...

nature.com
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