Hey, all of you with #Colon or #Rectal #Cancer. @MayoClinic we have a solution for You. youtu.be/14GMFM5sHaU

I’ve had a number of conversations with folks inside and outside government about the current situation with Anthropic, and here is what I believe to be true: — As we know, Anthropic publicly released its Mythos class models earlier this week under the commercial name Fable. — Fable is Mythos with guardrails. But if those guardrails fail, then you’ve exposed Mythos and its advanced cyber capabilities to people who shouldn’t have them. (Keep in mind that Anthropic itself widely promoted the idea that Mythos was a cyberweapon and needed to be regulated as such. They asked for government regulation of Mythos and championed the guardrails on Fable. If there is a vulnerability — big or small — it is Anthropic’s responsibility to patch.) — A highly credible trusted partner of both Anthropic and the USG who was testing Fable came forward with a jailbreak of those guardrails. The Admin asked Dario to fix the jailbreak or de-deploy the model. Dario refused. — In their blog post, Anthropic defended its decision by saying the jailbreak isn’t serious. That is not what the trusted partner and the USG believe; nor is that kind of minimizing language consistent with Anthropic’s brand as the AI safety company. It’s difficult to fathom how they could claim a jailbreak allowing operability of a cyber weapon could be defined as not “serious.” — In the past, Anthropic has always said that safety must be top priority and taken super seriously. In this case, Anthropic prioritized the continued offering of the consumer model over safety. — In reaction, the Admin issued the export control. The Admin did this reluctantly. It’s been very surprised that Anthropic hasn’t wanted to cooperate with a reasonable safety request (ie fixing the jailbreak issue). Anthropic’s reaction is very much at odds with their branding and ethos as a safe AI research community. — The Admin’s hope now is that Anthropic remediates the safety issue, the export control is lifted, and Fable goes back into general release. The Admin wants all of this to happen as soon as possible. It is frankly bewildered that Anthropic hasn’t wanted to comply with safety requests that it previously said were its highest priority. — Those trying to misdirect and tie this action to the prior DoW/Anthropic issues are wrong. The Admin values Anthropic’s technical capabilities and feels that this issue, while serious, should be easily resolved. The ball is in Anthropic’s court.

#AudioVisualAbstract : The Impact of RAS/BRAF Mutation on Pathological Complete Response After Total Neoadjuvant Therapy in #RectalCancer @Ibrahim_Gomaa95 @DrDavidLarson ow.ly/Jljp50Z8XAj @docgovind @SyedAAhmad5

We see encouraging discrimination, and promising performance after appropriate recalibration to account for differences in case-selection! 📈 We hope this is a step toward more individualized counselling and organ-preservation decision-making in rectal cancer care.

We trained an ensemble of state-of-the-art tabular foundation models to predict pathological status after TNT TME. We then applied this model in patients on a post-TNT W/W pathway, to assess its utility to predict persistent clinical complete response. 💻⚡️

Pleased to share our new model to guide decision-making after total neoadjuvant therapy in locally advanced rectal cancer, now pub'd in @AnnalsofSurgery! ⚡️ Paper 📝: journals.lww.com/annalsofsur… Online calculator 💻: chrisvarghese-pccr-estimator…

Couldn't have done this without my fiancé @JyiChengNg! 💪 Thanks to co-authors: @RichardSassun, @ThielsCA, @SalehinejadH, Dr William Perry, @KellieLMathisMD, @DrDavidLarson! Work from🏥 @MayoClinicSurg & 🔬 #SurgicalAI2 Lab!

#GooglNext2026 many new opportunities for healthcare and opportunities to strengthen @Google and @MayoClinic partnership

Human Complexity is truly Amazing. @MayoClinic

Ever wonder what predictors of Success for #RectalCancer look like? Take a look at a few of our recent publications @JyiChengNg @RichardSassun @MayoClinicSurg @MayoClinic @EricDozoisMD @merchea_md

#Robotics appears to help all aspects of complex #Diverticulitis and presentation, based on our recent #publications. @MayoClinicSurg @MayoClinic @SheriefShawkiMD @merchea_md @RichardSassun

These are my thoughts on #Diverticulitis given recent #publications at #MayoClinic @MayoClinicSurg @MayoClinic @RichardSassun @merchea_md

No better place to learn from @MayoClinicSurg colorectal surgery experts @DrDavidLarson @merchea_md @KellieLMathisMD then in Maui

Has been another successful meeting! Always an amazing time in paradise. Next year it’s on the Big Island! ce.mayo.edu/surgical-special…

Elon Musk predicts that Tesla Optimus robots will surpass today's best human surgeons within 3-4 years at scale. “There will probably be more Optimus robots that are great surgeons than there are all surgeons on Earth. I'm not absolutely certain, but if you say four years, I'd be absolutely certain.”

Robotic-assisted rectal cancer surgery is associated with superior short- and long-term outcomes, a large-scale study finds.📈 Compared to open and laparoscopic procedures, robot-assisted surgery had the lowest complication and mortality rates, the shortest hospital stays, and the highest 5-year overall survival and relapse-free survival.🇯🇵 onlinelibrary.wiley.com/doi/… #colorectalresearch #colorectalsurgery #AGSurg #SoMe4Surgery @SWexner @juliomayol

Nice paper by @Roy__Hajjar during his colorectal surgery fellowship @MayoClinicSurg @DrDavidLarson

Honored for being part of the scientific secretariat of this really passionate congress on #DiverticularDisease that took place in #Desio. A special thanks to my mentors @DrDavidLarson, Dario Maggioni, and @GiulioMari2, guiding me from the beginning and helping shaping my future.

Today I was at a nice and scientific sounds congress about #DiverticularDisease Congress in Desio, Milan Speaking of #SUDD surgical management Meeting again with @MayoClinic research fellows and celebrating our mentor @DrDavidLarson A special thanks to @GiulioMari2 for all

Great talk, thinking differently. Complex surgery with awake patients Dr Jacopo Crippa!

Classification of #diverticulitis by @AnneClair Sileo MD at Dazio clinical congress.