Computational oncologist working on understanding phenotypic differences between co-existing clones #crdlab @mathonco

Joined July 2012
103 Photos and videos
Pinned Tweet
Introducing ALFA-K for mapping karyotype fitness landscapes. We uncovered massive epistasis in karyotype evolution & estimated fitness of 272k karyotypes. Huge congrats to @Richard_J_Beck for crossing the finish line! nature.com/articles/s41467-0… #cancerevo #mathonco #MoffittResearch
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Noemi Andor retweeted
Live from #AACR25: Alexander Anderson, PhD, (@ara_anderson) leads the Adaptive Therapy from Board to Bench to Bedside and Back Again symposium. He shares how evolution-inspired treatment strategies like adaptive therapy can optimize drug use, delay resistance and improve outcomes across cancer types. #MoffittAACR25
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🎉Thrilled to share that our paper is featured on the cover of CancerResearch: aacrjournals.org/cancerres/i……Kudos to the entire team for this achievement, and a special shoutout to @zuzannows for the stunning cover design.​ Thanks to @theNCI @mathonco @MoffittResearch for the support

Finally out! Our 2022 @IMOworkshop-winning #teamviolet article is published in Cancer Research - a thread (1/n)
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Excited to see this out! Huge credit to @Zuzannows and Frederika for leading the way. Our S3MB model recapitulates GBM growth and karyotype evolution post-surgery, revealing how resource access shapes tumor ploidy. Grateful to have been part of this with such a fantastic team!
Finally out! Our 2022 @IMOworkshop-winning #teamviolet article is published in Cancer Research - a thread (1/n)
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Today at #ITCR2024 we looked at CLONEID’s role in collecting genotypic and phenotypic data. Use case demo was a long term evolution experiment led by @VuralTagal with Jackson Cole
Replying to @EinsteinCross
@EinsteinCross presenting her work at @NCI_CSSI #NCIITCR this morning. This is my first time here for our new U24 with @FertigLab, and I couldn't me more thrilled with this amazing cancer informatics community! @IUImpact @mathonco @theNCI
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Compelling talk from @benjraphael at the #ITCR2024 on quantification of spatial heterogeneity. Looking forward to using CalicoST to inform our mathematical models of chromosome mis segregations!
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Excited to share our software CLONEID at the #ITCR2024. CLONEID collects and maps genotypic and phenotypic data, across space & time. Use cases demonstrated by @thomasaveith and @Richard_J_Beck . Thanks to the #NCIITCR @theNCI for funding the work!
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Excited to announce that registration for the 12th @mathonco workshop on Treatment Toxicity is now open. Held onsite @MoffittNews Nov 3-Nov 8 #MoffittIMO more details: imo12.eventbrite.com. Deluxe travel awards are available on a competitive basis, apply by 09/30!
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Noemi Andor retweeted
It will be a great pleasure to attend and present at the 1st Polyploid Giant Cancer Cell Conference at the MD Anderson Cancer Center in Houston this week. @MDAndersonNews #Houston #Polyploidy #Cancer
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Todays @mathonco research in progress is from @EinsteinCross lab member Richard Beck presenting, Modelling the Evolutionary Landscape of Aneuploidy @MoffittNews
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If you are a High School student aged 16 or older and interested in learning how you can apply mathematics to cancer then consider applying to the @mathoncoblog fully funded High School Internship summer program @MoffittNews: moffitt.org/education/resear…
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Noemi Andor retweeted
A great study on the relationship between cancer cells, stroma and multifactorial drug resistance was presented by @AndriyMarusyk from Moffitt Cancer Center. @MoffittNews #AACRevol23 #AACR
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Noemi Andor retweeted
Congratulations to Ryan Schenck and Maureiq Ojwang for their talks at the AACR Special Conference in Boston! #AACREvol23 #AACR #cancerevolution
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Peter Laird From Van Andel Institute presents how global and local DNA methylation contributes to cancer development #AACREvol23 #AACR #CancerResearch
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Noemi Andor (@EinsteinCross) has been presenting the last seminar so the headliner of the 2023 AACR Special Conference "Translating Cancer Evolution and Data Science: The Next Frontier" and informs the audience on ALFA-K. #AACR #AACREvol23 #CancerEvolution #Aeneuploidy
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6 Dec 2023
.@EinsteinCross: ALFA-K is available on github - designed and implemented by @Richard_J_Beck #AACRevol23
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The final presentation of #AACREvol23 is from our very own @EinsteinCross presenting new work on, Adaptive local fitness landscapes for aneuploid karotype @mathonco @MoffittNews
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6 Dec 2023
.@val_boeva is talking next about "Unraveling potential genetic drivers of intratumor transcriptional heterogeneity and phenotypic plasticity in malignant cells" #AACRevol23
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6 Dec 2023
Laird: The slope of the hypomethylation with age was slightly different in different tissues, so the rate of hypomethylation per cell division may vary with organ biology/context #AACRevol23
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