Fumiko Esashi Lab at @Dunn_School, @UniofOxford. Curious about DNA repair, replication and chromosome segregation, the things that make us who we are.

Joined January 2020
19 Photos and videos
Ever wonder what’s happening at centromeres in resting cells? Our latest study, led by @xssaayman and in collab with @nussenza, demonstrates striking enrichment of DNA breaks at centromeres in quiescent human cells. Excited to share this work @MolecularCell now!
Online Now: Centromeres as universal hotspots of DNA breakage, driving RAD51-mediated recombination during quiescence dlvr.it/ShRC9b
11
62
239
52,919
Esashi Lab also @esashilab.bsky.social retweeted
10 Jun 2025
Thank Dr. Wan for an exciting talk. This week, Dr. Fumiko Esashi @EsashiLab will discuss centromere instability. Sign up and check out the 2nd half of the year schedule at cancer.columbia.edu/research…
1
4
10
930
This study, conceived 8 years ago, was made possible by a global collab across the UK, USA, Japan and Turkey. The team efforts of Emily and Lucia, relayed by Brian, Jacob, Emoke and Ramazan @rguendogdu, and invaluable assistance from many others, brought this research to life.
1
1
1
266
Huge thanks to everyone involved and the support from the community. We will be moving to another place 🦋- follow us there (@esashilab.bsky.social) if you are curious about what is going on in the Esashi lab!
1
147
Esashi Lab also @esashilab.bsky.social retweeted
We are pleased to inform you that the meeting “From Genome Instability to Cancer: A tribute to Angelos Constantinou” that will take place in Carry-Le-Rouet from March 10th to March 13th 2025 is now open for registration on the link: tribute2angelos.fr/page/home…
2
30
48
5,281
Great pleasure to share our unusual review article, discussing DNA repair in quiescent cells, out now online bit.ly/3McCj5e
2
18
91
8,443
We find interesting DNA repair mechanisms that are regulated differently in quiescent cells. Excellent work by two talented PhD students, Brian and Jacob, who have contributed equally. There is definitely a lot more to learn and we welcome any feedback you may have!
1
1
287
This is our contribution to the Special Issue 'Cutting Edge Perspectives in Genome Maintenance XI' @repair_dna, edited by Penny Jeggo. We thank Penny for this great opportunity!
244
Esashi Lab also @esashilab.bsky.social retweeted
Programme: June 4, Cell Cycle Club meeting! PROGRAMME (digital & in-person) 4 talks: Barr, @PinesLab, @lab_baum, & Novak labs 1 Keynote: @EsashiLab IN-PERSON @TheCrick Tea/coffee & poster session Networking & drinks REGISTER (FREE) @abcam events.abcam.com/event/bfdb7…
1
8
17
2,876
Thrilled to be part of the project - big congrats to Dani & everyone involved!
1
4
1,051
Esashi Lab also @esashilab.bsky.social retweeted
#1 Happy to share our work “Specialized replication mechanisms maintain genome stability at human centromeres” @MolecularCell from A. Scelfo, A. Angrisani and T. Wilhelm @institut_curie @CNRS where we provide the causes of centromere fragility. authors.elsevier.com/a/1iba6…

19
37
130
15,411
Happy to share our review article, discussing DNA strand breaks at centromeres🧬Are they all toxic? We explore their origins and impact across cell cycle stages and quiescence - open access⬇️ doi.org/10.1016/j.semcdb.202…

14
48
3,834
Ever wonder what’s happening at centromeres in resting cells? Our latest study, led by @xssaayman and in collab with @nussenza, demonstrates striking enrichment of DNA breaks at centromeres in quiescent human cells. Excited to share this work @MolecularCell now!
Online Now: Centromeres as universal hotspots of DNA breakage, driving RAD51-mediated recombination during quiescence dlvr.it/ShRC9b
11
62
239
52,919
🔬Excited to share the much-requested step-by-step exo-FISH protocol, now in @STARProtocols! Led by @xssaayman, meticulously tested by Emily & Brian, and enriched through peer reviews. 📝 DNA breaks at repetitive regions🧬 Let's advance together! 🚀🚀sciencedirect.com/science/ar…

2
6
807
Esashi Lab also @esashilab.bsky.social retweeted
Our latest📰! Out today in @MolecularCell We used single-molecule imaging to directly observe human BRCA2 tumour suppressor in action! Spearheaded by @BelanOndrej & @LukeGreenhough. A thread. (1/10) sciencedirect.com/science/ar…
5
61
261
48,170
🎓🎉 Huge congratulations to Emily on successfully defending her DPhil thesis! 🙌🥳Special thanks to the brilliant examiners, Peter Thorpe (@Thorpelab) and Chris Norbury (@NorbsOx), for their insightful discussion. Well done, Emily! 🍾🥂
2
2
23
1,841
Looking for #postdocposition? Excited about R-loop biology? Still, 10 days to apply for an MRC-funded position in the Gromak Lab! @Dunn_School ⬇️⬇️
And another postdoc opportunity! Join the Gromak lab and help investigate the role of R-loop biology in health and disease. More info about the group here: sites.google.com/view/gromak… Deadline: 12th May Advert: my.corehr.com/pls/uoxrecruit… Please share!
5
5
2,151
Many congrats Ramazan🎉Look forward to working with you soon!
Very happy to get @Tubitak postdoctoral fellowship to have a chance to work @EsashiLab @UniofOxford @bingoluni2007 Thank you for the support @TubitakBIDEB @ProfHasanMandal @OFUrsavas
1
2
4
1,254