Molecular Cell is a Cell Press journal that aims to publish the best papers in molecular biology.
Joined April 2013
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Molecular Cell retweeted
Jun 8
🚨 Today we report cryo-EM structures of Bxb1 integrase complexed with its attB/attP DNA substrates before, during and after recombination.
We engineer Bxb1 mutants with improved recombination and altered sequence recognition properties.
Out today @MolecularCell ⬇️
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Molecular Cell retweeted
Jun 12
Excited to share that our preprint 'RNA reinforces condensate nucleation on chromatin to amplify oncogenic transcription' is now online @MolecularCell cell.com/molecular-cell/full… @PennMedCSO @PennCancer @PennEpiInst
4 Aug 2025
(1/n) Excited to share our new preprint! We uncover that RNA actively promotes nucleation and function of pathogenic condensates, amplifying locus-specific oncogenic transcription and promoting tumorigenesis. #epigenetics #condensates #cancer #RNA biorxiv.org/content/10.1101/…
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Jun 12
Online Now: RNA reinforces condensate nucleation on chromatin to amplify oncogenic transcription dlvr.it/TT0yzt
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Online Now: Distinct associations of pioneer factor Ascl1-E12a with nucleosomes drive changes in cell fate dlvr.it/TT0t7k
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Jun 11
Explore the latest research from the NIH SenNet consortium, working to identify and characterize senescent cells across the human body, lifespan, and states of health and disease. @sennetresearch
View the collection: hubs.li/Q04l2Z670
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Jun 11
Featuring Commentary "Charting Human Cellular Senescence in Aging and Disease" from @vidyani8 Vidyani Suryadevara, Rong Fan, and colleagues in @cellcellpress
cell.com/cell/fulltext/s0092…
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Online Now: SenCat: Cataloging human cell senescence through multi-omic profiling of multiple senescent primary cell types dlvr.it/TT04z8
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Online Now: Structure and engineering of the large serine recombinase Bxb1 for gene integration dlvr.it/TSxXmC
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Everything you always wanted to know about plasmid chromatinization … but were afraid to ask dlvr.it/TSxQQv
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RNAP at the apex: Cryo-ET unveils the torsional tango between plasmid DNA and double-helix-melting proteins dlvr.it/TSxKTl
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Use it or lose it: A ubiquitin-mediated autophagy pathway for degradation of MHC-I in pancreatic cancer dlvr.it/TSxCCk
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Mitochondria across the globe: Diverse voices, shared energy dlvr.it/TSx6ZS
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A multi-subunit autophagic capture complex facilitates degradation of ER-stalled MHC class I in pancreatic cancer dlvr.it/TSx1jd
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Join speaker Martin Beck @MPIbp at #CS3Dbiologicalfunction2026.
Martin’s cutting-edge research combines cryo-ET, structural proteomics and computational modeling to uncover how molecular machines function within cells.
Abstract deadline: July 3, 2026
hubs.li/Q04ksBXs0
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Uncovering the initial response: Intra-mitochondrial surveillance activates the UPRmt dlvr.it/TSvnjL
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Chromatin architectures underlying plasmid-based assays for regulatory variant effects dlvr.it/TSvDv7
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Hypoxia-driven lncRNA SHIELD promotes GPX4 translation and protects against ferroptosis in hepatocellular carcinoma dlvr.it/TSv82y
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In vivo single-cell ribosome profiling reveals cell-type-specific translational programs during aging dlvr.it/TSv1b2
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