We love DNA, RNA and their protein partners.
Joined August 2019
- Tweets 16
- Following 0
- Followers 396
- Likes 13
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13 Jul 2022
Highlights the awesome power of NMR and cryo-EM combined to make the "invisible" visible.
13 Jul 2022
Happy to share our latest paper on the cryo-EM structure of a telomere end replicon: Tetrahymena telomerase-CST-Pola-Primase. Active for coordinated G-strand and C-strand synthesis. nature.com/articles/s41586-0…
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13 Jul 2022
Big congratulations to current and former @FeigonLab members @YaoHe_YH @HeSong2009 HenryChan @Baocheng_Liu @YaqiangWang LukasSusac and great collaborator @zhou_lab !!!
13 Jul 2022
Happy to share our latest paper on the cryo-EM structure of a telomere end replicon: Tetrahymena telomerase-CST-Pola-Primase. Active for coordinated G-strand and C-strand synthesis. nature.com/articles/s41586-0…
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13 Jul 2022
Great to be part of today’s trifecta of @Cechlab @cijilim @FeigonLab Nature papers on telomere C-strand synthesis by CST-Pola-Primase!
nature.com/articles/s41586-0…
nature.com/articles/s41586-0…
nature.com/articles/s41586-0…
13 Jul 2022
Happy to share our latest paper on the cryo-EM structure of a telomere end replicon: Tetrahymena telomerase-CST-Pola-Primase. Active for coordinated G-strand and C-strand synthesis. nature.com/articles/s41586-0…
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13 Jul 2022
Happy to share our latest paper on the cryo-EM structure of a telomere end replicon: Tetrahymena telomerase-CST-Pola-Primase. Active for coordinated G-strand and C-strand synthesis. nature.com/articles/s41586-0…
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3 Jun 2022
Happy to be at the #RNA2022 #RNA22
@RNASociety meeting to share our 7SK @AuroraYuanYang and telomerase work. Check out @Baocheng_Liu 's talk C11-10 and @YaoHe_YH 's poster PS3-496 today for telomerase. Also had a beautiful hike in Boulder!
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13 Apr 2022
Happy😊to share our work on human telomerase with shelterin protein TPP1 @Nature. Our cryo-EM structures define the determinants of telomerase recruitment by TPP1, TERT–TER interactions, and structural basis of telomerase inhibitor & telomeropathies. rdcu.be/cLheF
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23 Mar 2022
Super excited to share our work on 7SK core RNP structures and conformational switching published @MolecularCell. These cryo-EM structures are the first for 7SK RNP, providing structural and mechanistic insights for 7SK RNP assembly and P-TEFb regulation. authors.elsevier.com/c/1ena7…
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23 Mar 2022
For LaRP enthusiasts @LarPsociety, the structures include the first full-length La-related protein.
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1 Jun 2021
Beautifully written review by Michael Stone on the recent cryo-EM structures of telomerase from our lab and Nguyen's lab.
28 May 2021
Cryo-EM structures tell a tale of two telomerases: A News & Views by Michael D. Stone and colleagues @ucsc discusses two recent papers in @nature reporting #telomerase #cryoEM structures by @KellyTHD_Nguyen and @FeigonLab
nature.com/articles/s41594-0…
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12 May 2021
Feigon lab is excited to share our paper: Structures of telomerase at several steps of telomere repeat synthesis. Congratulations @YaoHe_YH @YaqiangWang @Baochen66151807 Christina, Lukas, and Ryan. #telomerase #cryoEM @uclachem @nature nature.com/articles/s41586-0…
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4 Dec 2020
Feigon Lab is hiring! Prospective postdocs with experience in NMR and interest in integrative structural biology of RNA or RNA-protein complexes. Applicants with expertise in crystallography or cryoEM also welcome. Email feigon@mbi.ucla.edu with CV and names of 3 refs. @nmr900
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2 Dec 2020
Congratulations to @yaqiangwang, @MGJones13, Lukas, @HeSong05808037 @uclachem on our new publication in PNAS. Our study shows that TERT TEN and TRAP motif have coevolved and are hallmarks of functional telomerase. doi.org/10.1073/pnas.2011684…
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Feigon Lab retweeted
28 Aug 2019
In the integrated #structuralbiology session in Max Kade Auditorium, Juli Feigon @uclachem talks about #NMR and X-ray studies of RNA-protein complexes. conference.euroismar2019.org…
- photo by @LindFT
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21 Aug 2019
Postdoc position available in #FeigonLab for experienced and motivated NMR spectroscopist interested in integrative structural biology of RNA-protein complexes. Email feigon@mbi.ucla.edu with CV and names of 3 refs.
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20 Aug 2019
Joining the modern age - our first tweet and first bioRxiv preprint. Structure of S. pombe telomerase protein Pof8 C-terminal domain is an xRRM conserved among LARP7 proteins biorxiv.org/content/10.1101/…
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