Senior Investigator @NIEHS Intramural. Physician scientist. Heads #innateimmunity #Fesslerlab in RTP, NC. #Macrophage #Immunometabolism Opinions are my own.
Joined January 2021
- Tweets 78
- Following 142
- Followers 161
- Likes 138
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Michael Fessler, MD retweeted
30 Jul 2024
๐ฃ CALL FOR PAPERS-Climate Change
Showcasing papers that investigate the mechanisms by which environmental climate change-related factors impact lung health and disease
Deadline is October 1, 2024
More information here:
bit.ly/3whoGx4?
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Michael Fessler, MD retweeted
19 Mar 2024
#ResearchLetter:
Sterol biosynthesis regulates TLR signaling and the innate immune response in a Smith-Lemli-Opitz syndrome model: buff.ly/4axZRM7
@FesslerMd @NIEHS
#Immunology #Inflammation
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Michael Fessler, MD retweeted
22 Dec 2023
๐ฃ CALL FOR PAPERS-From Multi-Omics to Mechanisms of Lung Disease ๐ฃ
Focusing on the use and impact of multiple omics technologies associated with respiratory diseases, lung development, and precision medicine strategies.
Deadline is March 1, 2024
bit.ly/3v7DAVL
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Michael Fessler, MD retweeted
19 Dec 2023
Meta-Analysis of COVID-19 BAL Single-Cell RNA Sequencing Reveals Alveolar Epithelial Transitions and Unique Alveolar Epithelial Cell Fates
๐ Open Access
๐ bit.ly/47ZhLWA
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Michael Fessler, MD retweeted
11 Dec 2023
Endogenous and Therapeutic 25-Hydroxycholesterols May Worsen Early SARS-CoV-2 Pathogenesis in Mice
๐ Open Access
๐ bit.ly/3GuJa70
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Michael Fessler, MD retweeted
5 Nov 2023
#WeekendRead! #InterferonPower ! Fessler &co show โฆ@jclinicalinvestโฉ that IRGM1 prevents excessive type I #IFN production & macrophages lytic death/necroptosis, allowing the differentiation of mature macrophages during bacterial infections! jci.org/articles/view/171982โฆ
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Michael Fessler, MD retweeted
6 Dec 2023
Meta-Analysis of COVID-19 BAL Single-Cell RNA Sequencing Reveals Alveolar Epithelial Transitions and Unique Alveolar Epithelial Cell Fates
๐ Open Access
๐ bit.ly/47ZhLWA
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3 Dec 2023
Our latest paper, led by talented Peer Karmaus with help from @Tatalab_Duke @TataAleksandra and other collaborators: atsjournals.org/doi/10.1165/โฆ
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3 Dec 2023
IF staining of patient lungs confirmed the AT1 cell state. Interesting implications for unexpected repair pathways in lung and perhaps for diagnosis and therapy. @AJRCMB
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Michael Fessler, MD retweeted
2 Nov 2023
1/7 Latest paper in @CellStemCell! Transitional cell states sculpt tissue topology during lung regeneration. This work was jointly led by @arvikonk @KonishiSatoshi @TataAleksandra & Lauren with help from colleagues in our lab and collaborators @Duke tinyurl.com/4xhbm3zw
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Michael Fessler, MD retweeted
2 Oct 2023
Check out the line-up for the Gordon Research Conference on Immunometabolism! Excited to co-lead this with @LynnHedrickAU @PCHo_Lab & Nancie MacIver.
Mark your calendars--Registration is open!
grc.org/immunometabolism-in-โฆ
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16 Sep 2023
Pleased to announce the latest work of talented Prashant Rai @mitoimunfection just published in @jclinicalinvest : jci.org/articles/view/171982. We show that IRGM1 supports #hostdefense against intracellular #bacteria by suppression of type I #interferons!
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16 Sep 2023
This counters the longstanding paradigm of IRGM1 as an #interferongamma cell-autonomous antimicrobial protein. Exciting implications. Thanks to our collaborators @mayer_barber and Greg Taylor.
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Michael Fessler, MD retweeted
15 Sep 2023
Our latest brief report: type i interferon is the key factor that drives susceptibility to intracellular bacterial infection in an autoimmune IRGM1-deficient mice !
#type1interferon #Fesslerlab @FesslerMd
Thanks to our collaborators !
๐ @mayer_barber lab @ Greg Taylor lab
12 Sep 2023
IRGM1 supports host defense against intracellular bacteria through suppression of type I interferon in mice dlvr.it/Sw19p7
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Michael Fessler, MD retweeted
12 Aug 2023
Our study โฌ๏ธ
Race specific association of IRGM risk allele (implicated in Crohns and other diseases), with increased cytokine expression in AAs.
Bottom line: Underscores the importance of inclusion in genetic studies of immunity
@FesslerMd
@bcm_gihep
nature.com/articles/s41598-0โฆ
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17 Jun 2023
Exciting Senior Clinician opportunity at @NIEHS /NIH. Looking for physician scientist interested in grant-free, well-supported research leadership role. Apply on USAJobs.gov from 6/26โ7/5 under โSupervisory Physician (Clinical)โ in Durham, NC: niehs.nih.gov/careers/jobs/sโฆ
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Michael Fessler, MD retweeted
No #ENDO2023 live-tweeting for me this morning...because I'm chairing SY032, Orphan Nuclear Receptors at the Crossroads of Inflammation, Immunity, and Cancer. Come see 3 great talks from @Eva46653369 @FesslerMd @mwilli323 starting at 10:30AM, McCormick W178A
ALT photos of presenters and Venn diagram of their overlapping scientific expertise.
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7 Mar 2023
Want to be a Tenure Track Investigator at NIH? Apply to be a TTI in immunology at NIEHS/NIH. Great resources and work environment. DM with questions; please RT. Details: hr.nih.gov/jobs/search/scienโฆ
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28 Apr 2023
Approaching the final week to apply for our Tenure-Track Investigator vacancy at intramural NIEHS/NIH!!
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ASCI member Michael B. Fessler @FesslerMd @NIEHS in @JCI_insight: 25-Hydroxycholesterol exacerbates vascular leak during acute lung injury: buff.ly/3KsSNov
#Inflammation #Pulmonology
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