Twitter account of the Fiedler group. (student handled)
Joined August 2020
- Tweets 50
- Following 42
- Followers 333
- Likes 79
8 Photos and videos
1 Aug 2024
During our investigation of protein pyrophosphorylation, we identified a novel post-translational modification (PTM), which we have termed 'Protein Oligophosphorylation'.
biorxiv.org/content/10.1101/…
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1 Aug 2024
To substantiate our findings, we collaborated with @PhosphorusFive @CEStieger and @daniel_roderer @FelixSchoepf to obtain mass spectrometry spectra and the first-ever Cryo-EM structure of pyro-and oligo- phosphorylated proteins.
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1 Aug 2024
We would also like to thank all the people involved in this study. @MRuwolt @theliulab @JeremyAMMorgan
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25 Apr 2024
Happy to share our latest paper on protein pyrophosphorylation - yes, it exists! It has been a long journey with many wonderful co-workers and collaborators. Thank you all!
@JeremyAMMorgan @MRuwolt
nature.com/articles/s41589-0…
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25 Apr 2024
Together with the paper checkout this „News&Views“ article about the „Pyrophosphomania“!
nature.com/articles/s41589-0…
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11 May 2024
Follow up to our discovery of endogenous protein pyrophosphorylation, Arif Celik, a PhD student from our lab, decided to select one of the newly found „pyrophosohoproteins“ and see what effect does this PTM have on protein activity.
pubs.acs.org/doi/10.1021/jac…
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11 May 2024
On the way to understanding the role of pyrophosphorylation, he also discovered a new mode of protein pyrophosphorylation! Thank you Arif for the hard work!
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Fiedlerlab retweeted
6 Nov 2023
📢Vortrag: Wer quasselt da? Wie Zellkommunikation funktioniert, Prof. Dr. Dorothea Fiedler @FiedlerLab
Für Lehrkräfte, Schüler:innen & Wissbegierige
📍 Kinosaal des Zeiss-Großplanetariums,Berlin
🕓16 Uhr, 7. Nov. Eintritt: Kostenlos!
📝 ticket@planetarium.berlin
#BerlinSciWeek
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21 Oct 2023
After a lot of efforts from our former post doc Sarah Hostachy, we are do happy to see this out!
Fluorination Influences the Bioisostery of Myo-Inositol Pyrophosphate Analogs (Dorothea Fiedler and co-workers) @FiedlerLab @LeibnizFMP onlinelibrary.wiley.com/doi/…
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17 Oct 2023
Unexpected results often lead to fascinating discoveries!
Have a look at this new paper from our lab where @timaguirre_chem developed an inhibitor for IP6Ks and found out some really cool mechanistic details about the inhibition
elifesciences.org/articles/8…
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6 Oct 2023
The group retreat begins with a ~ 40 km bike ride thru a beautiful forest! 🚵♀️🚵🚵♂️
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7 Oct 2023
After the amazing bike ride and an even better scientific session, it was barbecue time :)
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Fiedlerlab retweeted
27 Sep 2023
📢Exciting talk alert! Maja Köhn @MAJAFL @UniFreiburg will delve into "Function, selectivity & chemical targeting of protein phosphatases.”
This Friday, September 29th, 3:00 pm. Join us on Zoom! Meeting-ID: 963 0761 9443, Kenncode: 550079
#ScienceTalk @PhosphorusFive @FiedlerLab
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Fiedlerlab retweeted
5 Sep 2023
Congratulations to Minh Nguyen Trung @FiedlerLab for a wonderful defense of his PhD "Elucidation of Inositol Polyphosphate Dephosphorylation Pathways using Stable-Isotope Labelling and NMR spectroscopy" What a journey! Grateful to have been part of the evaluation committee🍾🥞😀
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5 Sep 2023
Congratulations Minh for successfully defending your PhD! A very well deserved “summa cum laude” and thank you so much for contributing towards unveiling of the black box of inositol polyphosphate metabolism :)
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Fiedlerlab retweeted
27 Jun 2023
Dorothea Fielder @FiedlerLab is up here next at #ISMSC2023 with a really interesting talk on inostol pyrophosphates and their different signaling functions.
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