Structural biologist and protein biochemist. Interested in bacterial pathogenesis and host-microbiome interactions. Junior Group Leader at @LeibnizFMP.

Joined April 2018
6 Photos and videos
Daniel Roderer retweeted
17 Dec 2024
We are very grateful for this exciting opportunity provided by Leibniz Cooperative Excellence. Looking forward to new collaborations through this framework. Within this funding opportunity, we have one job opening for a PhD student or Postdoc: leibniz-fmp.softgarden.io/jo…

Exciting news! @LeibnizFMP, @kieluni & @LeibnizLIV are starting new project, supported through "Leibniz CooperativeExcellence" program. Goal: Unravel mechanisms of K2P potassium channels – with potential new therapeutic approaches. leibniz-fmp.de/newsroom/news… #LeibnizWGL @HanSun_lab
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Daniel Roderer retweeted
🎉 Herzlichen Glückwunsch! Prof. Volker Haucke @VolkerHaucke erhält den #LeibnizPreis 2025 der @dfg_public für seine bahnbrechende Forschung zu #Lipidsignaling & synaptischer Signalübertragung. 👏 #Wissenschaft #Forschung
Herzlichen Glückwunsch zum #LeibnizPreis! 10 Wissenschaftler*innen gebührt große Ehre. Sie erhalten je 2,5 Mio. Euro für ihre #Forschung. Die Verleihung feiern wir am 19. März in #Berlin – zusammen mit vielen bisherigen Preisträger*innen aus #40JahreGWL. ➡️dfg.de/de/service/presse/pre…
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Daniel Roderer retweeted
25 Nov 2024
Sebastian Tacke has been honored with the Paper of the Year Award by the Journal of Structural Biology @ElsevierConnect for his innovative technical developments in the field of #cryoET #cryoEM Congratulations! #teamtomo
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Daniel Roderer retweeted
Ich möchte nur kurz daran erinnern, dass dieser Zug in meiner Kindheit aus politischen Gründen unmöglich gewesen wäre, und ich finde, wir sollten - allen Problemen und Meinungsverschiedenheiten und Streitereien zum Trotz - dankbar sein, dass er heute eine Selbstverständlichkeit ist.
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Daniel Roderer retweeted
I am happy our new manuscript on intrinsically disordered proteins in #endocytosis is now out on BioRxiv #NMR @LeibnizFMP
Competitive interactions between Eps15 EH domains and intrinsically disordered proteins generate a complex interaction network biorxiv.org/cgi/content/shor… #biorxiv_biophys
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RT @martingommel: 🚬 An die Raucher:innen, die kommentieren, dass ich mich ja woanders hin bewegen soll, wenn ihr an der Haltestelle qualmt:…
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Daniel Roderer retweeted
We have a new paper for you: “Structure of tetrameric forms of the serotonin-gated 5-HT3A receptor ion channel”. Here we found that the prototypical pentameric ligand gated ion channel can form stable tetramers and characterized it with cryo-EM/ET and molecular simulations.
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Are you interested in the structural background of the host-microbiome interaction and searching for a PhD position in an exciting scientific community? Then look no further and apply at the @LeibnizFMP! Please find details here: leibniz-fmp.de/fileadmin/Dat…

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Daniel Roderer retweeted
Happy to start working with new 1,2 GHz NMR spectrometer - perfect for precise analysis of complex biological systems like #proteinstructures ! Peter Schmieder, @HanSun_lab , Adam Lange, @MillesSigrid , Hartmut Oschkinat Read more 👇 leibniz-fmp.de/newsroom/news…
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Daniel Roderer retweeted
11 May 2024
Follow up to our discovery of endogenous protein pyrophosphorylation, Arif Celik, a PhD student from our lab, decided to select one of the newly found „pyrophosohoproteins“ and see what effect does this PTM have on protein activity. pubs.acs.org/doi/10.1021/jac…
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Daniel Roderer retweeted
25 Apr 2024
Happy to share our latest paper on protein pyrophosphorylation - yes, it exists! It has been a long journey with many wonderful co-workers and collaborators. Thank you all! @JeremyAMMorgan @MRuwolt nature.com/articles/s41589-0…
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Daniel Roderer retweeted
FMP Retreat 2024! 🎉A big thank you to everyone who joined us. It was fantastic to see all of you presenting your science, exchanging ideas, and getting to know one another. Your enthusiasm & contributions made this event a huge success! #FMPRetreat2024 #science📸Maria Jäpel
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Daniel Roderer retweeted
22 Apr 2024
📢Time to voice our concerns about the #WissZeitVG once again! ➡️17 scientific societies, which together represent more than 55,000 scientists, are speaking out! 👉Please share our initiative! 🔁Please RT
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Daniel Roderer retweeted
17 Apr 2024
Finally published! Delighted to introduce CLASP: a novel framework for spatial proteomics. Using XLMS we unveiled intricate protein localizations & topologies in mitochondria. CLASP offers higher resolution and throughput than BioID/APEX. nature.com/articles/s41467-0…
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Daniel Roderer retweeted
Check out our new paper on a previously unknown function of the type 1 pilus assembly platform FimD! Many thanks to everybody involved in this terrific collaboration with the labs of Gabriel Waksman, Manuela Hospenthal, Beat Meier and Thomas Wiegand. rdcu.be/dD7C6

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Daniel Roderer retweeted
13 Mar 2024
The 1.2 GHz NMR spectrometer has arrived at FMP Berlin. 😀 (Photo copyright: Adam Lange)
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This groove is closed by the unstructured N-terminus. At the membrane-distal end, the b-helix ends in a matchstick-like thickening. By combining cryo-EM, structure prediction, molecular docking, and MD simulation, we identify the binding sites of the two Fap2 receptors ...
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... TIGIT and Gal-GalNAc on two sides of the matchstick head. From this, we can deduce a model on how F. nucleatum applies Fap2 both as a molecular spear against immune cells and a molecular grappling that attached it to tumors.
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