Happy to drop this in the New Year. Learn how the “tough momma” regulates her house. @JExpMed @Dukeneurosurg rupress.org/jem/article-abst…

A special issue curated by guest editor @FilianoLab at @Dukeneurosurg highlights nine reviews discussing the multi-directional communication that occurs between the central nervous system, the surrounding tissues, and the immune system. Read it now: ow.ly/GTNh50YNzTC

Was a blast guest editing this special issue for @J_Immunol . Check out these amazing reviews on brain border sites. academic.oup.com/jimmunol/ar…

Check out our new preprint on a novel neuro-immune niche that underpins touch sensation.

Immune System Gene Linked to Hyperactivity, ADHD and Autism Researchers have identified a link between the immune system and hyperactive behaviors, highlighting the role of the STAT1 gene in regulating behavior. STAT1, a key regulator in immune responses, appears to influence brain development and function, particularly in dopamine neurons responsible for learning, memory, and motivation. In mouse studies, prolonged activation of STAT1 during embryonic development led to hyperactivity, fewer neurons, and reduced neural activity in critical brain regions. The findings suggest that disruptions in STAT1 signaling may contribute to neurodevelopmental disorders like autism and ADHD. Researchers are now exploring whether the STAT1 pathway could be targeted for future therapies.

Study in Mice Links Immune System to ADHD, Neurobehavioral Conditions corporate.dukehealth.org//ne…

New study from @FilianoLab links immune system to neurobehavioral conditions: "This work may have implications for ADHD, autism, and schizophrenia and open doors for investigating other conditions like Parkinson’s and substance abuse disorder." neurosurgery.duke.edu/news/s…

Check out our review "Mechanisms and risk factors for perinatal #allergic disease", led by Jozef and with @Abhay_R_. I♥️ how he simplified the complexities of allergies at the #maternal/#fetal & maternal/#infant interface. Authors' link for full access: authors.elsevier.com/sd/arti…

Today I was discussing the evolutionary differences in the mouse and human brains. Please feel free to use this in your lectures. Really, you don’t even need to give me credit.

Did you know that the fetal immune system can protect from congenital infection before birth? -Proud to share our study identifying protective functions of #microglia, contrasting the harmful early influence of #monocytes and primitive macrophages to #zika virus infection.

Thrilled to share new work from our lab led by ⁦@mitchkim_mw⁩! The results provide new insight to immune privilege and hopefully diagnostic/therapeutic tools || Endogenous self-peptides guard immune privilege of the central nervous system | Nature nature.com/articles/s41586-0…

Hyunjung Min et al. @FilianoLab reveal a mechanism by which mural cell–#macrophage interactions regulate the trafficking of CNS antigen-specific T cells to the dura. hubs.la/Q02Tfxbb0 📘 In our #Autoimmunity collection: hubs.la/Q02TfwNt0

Hyunjung Min et al. @FilianoLab reveal a mechanism by which mural cell–#macrophage interactions regulate the trafficking of CNS antigen-specific T cells to the dura. hubs.la/Q02RDb4D0 📘 In our #Neuroscience collection hubs.la/Q02RD9SC0 #SfN24

🚨UVa Neurodegeneration job alert!! UVa Neuroscience is hiring multiple TT faculty in neurodegenerative disease research. If you're looking for a vibrant scientific community with wonderful colleagues then check it out! Please share/rt! @uvavpr @BIG_Center_UVA @UVANeurology

The Dou lab at @ImmunologyDuke @dukemedicine is now recruiting new members! Join the team in deciphering the "lncs" between lncRNAs and autoimmunity! #rna #autoimmune #postdocjobs #AcademicTwitter careers.duke.edu/job/Durham-…

Our new work published today @NatrureMedicine nature.com/articles/s41591-0… The work led by Neta Rosenzweig (@NetaRose11) and Kilian Kleemann (@KilianKleemann). Thanks to our collaborators @EggenBart, @BlurtonJonesLab, @ReisaSperling @weinerlabhms @NowarskiLab

Grateful for this suppport from the @Rosenau_Fdn . Hoping this work translates to help those living with #Krabbe.

📢 I'm hiring postdocs/Sr. Research Associates for my Nutritional & Behavioral Epigenetics Lab at @UTSWMedCenter!!❤️‍🔥 If you're passionate about the neuroepigenetic regulation of appetite during obesity and aging I'd love to potentially work with you 🫵🏾 Please RT/share 🙏🏾