Thrilled to share our invited Nature Reviews Neuroscience review on the role of peripheral immunity in Alzheimer’s disease. Honored to write this piece with outstanding colleagues @KuchrooLab, @RudyTanzi, @weinerlabhms, Mehdi Jorfi and rising stars from my lab Neta Rosenzweig and Kilian Kleemann. My sincere thanks to Editor Katherine Whalley for the invitation. The time has come to deeply investigate peripheral immunity in AD.

organoids, while a powerful tool for studying human biology, lack immune systems, which is a significant limitation. NIH prioritized organoids to model human tissues and diseases in vitro. However, their lack of an immune system hinders their ability to fully recapitulate human physiology, especially for studying immune-related processes or diseases involving immune responses, like Alzheimer’s and Cancer

Thrilled to share invited review with the brilliant @NetaRose11! in the @ImmunityCP special issue on neuroimmune interactions. We explore shared immune pathways in Alzheimer’s & AMD, and chart new directions for cross-disease therapeutic strategies. cell.com/immunity/fulltext/S…

Online now: Alzheimer’s disease and age-related macular degeneration: Shared and distinct immune mechanisms dlvr.it/TKZSH4

Common immune system mediated threads of Alzheimer's disease and age-related macular degeneration, a new open-access review cell.com/immunity/abstract/S… @ImmunityCP

APOE4-dependent neutrophil-microglia interactions drive cognitive impairment in female individuals with Alzheimer’s disease via IL17F @ButovskyLab, @OlegButovsky, @NetaRose11, @KilianKleemann #neutrophils, #microglia, #IL-17 nature.com/articles/s41591-0…

Research Spotlight: Uncovering How a Cellular Miscommunication Leads to Cognitive Impairment in Female Patients with Alzheimer’s Disease buff.ly/4d1NmJT @ButovskyLab @OlegButovsky @NetaRose11 @KilianKleemann

Sex-Dependent APOE4 Neutrophil–Microglia Interactions Drive Cognitive Impairment in Alzheimer’s Disease stemcellsciencenews.com/news… via @Science News

This work led by Neta Rosenzweig (@NetaRose11), @KilianKleemann, & Thomas Rust provides a translational basis to target IL-17F in APOE ε4 female carriers with cognitive impairment. 🧠 Congratulations to all the authors! @OlegButovsky @EggenBart go.nature.com/4eZef2H

Any Clinical development incoming of bimekizumab for Alzheimer Disease @UCB_France ?

Sex-dependent APOE4 neutrophil–microglia interactions drive cognitive impairment in Alzheimer disease nature.com/articles/s41591-0…

APOE4-dependent neutrophil-microglia interactions drive cognitive impairment in female individuals with Alzheimer’s disease via IL17F @ButovskyLab, @OlegButovsky, @NetaRose11, @KilianKleemann #neutrophils, #microglia, #IL-17 nature.com/articles/s41591-0…

Our new work published today @NatrureMedicine nature.com/articles/s41591-0… The work led by Neta Rosenzweig (@NetaRose11) and Kilian Kleemann (@KilianKleemann). Thanks to our collaborators @EggenBart, @BlurtonJonesLab, @ReisaSperling @weinerlabhms @NowarskiLab

Another tour de force from @OlegButovsky lab further expanding our understanding of the APOE biology in Alzheimer’s disease. Congrats to the entire team of authors!

Our new work published today @NatrureMedicine nature.com/articles/s4159… The work led by Neta Rosenzweig (@NetaRose11) and Kilian Kleemann (@KilianKleemann). Thanks to our collaborators @EggenBart, @BlurtonJonesLab, @ReisaSperling @weinerlabhms @NowarskiLab

Sex-dependent APOE4 neutrophil–microglia interactions drive cognitive impairment in Alzheimer’s disease @NatureMedicine nature.com/articles/s41591-0…

APOE4 locks microglia in a state of homeostasis, preventing them from clearing amyloid plaque or beckoning astrocytes to help. Deleting APOE4 stirred microglia to dispose of plaques and tau tangles. @BrighamWomens @MayoClinic @hkust ow.ly/YwlG50Q18O9

אתה יודע מה היופי. שגם אם דעתי שונה משלך, אלמד להקשיב ולקבלה. שתזכה להתחדש כל פעם מחדש לטובה🌷 קודם כל לחתור להחזיר את כל השבויים. ולהפוך את רחל אדרי לראש הממשלה🙃

Dear Harvard Community and Alumni, We, the Israeli students at Harvard College, are reaching out to you during a time of profound grief and urgency. Over the weekend, the community of Kfar Azza, situated right next to the Gaza border, experienced an unimaginable tragedy.

During this darkest hour, the Sun encourages you to join us in extending a helping hand to the Israeli kibbutzim as they begin their long journey to recovery. kibbutzim-appeal.postedstuff…