Vascular biologist at University Health Network
Joined June 2020
- Tweets 581
- Following 511
- Followers 863
- Likes 1,222
24 Photos and videos
Jason Fish retweeted
May 1
Very excited to share chapter 1 of our endothelial identity story out now in @GenomeMedicine !!
Here we show that ERG governs dynamic and reversible EndMT in arterial ECs to limit endothelial dysfunction: link.springer.com/article/10…
@FishLab_UHN @kat_howe @Kristen_ESchulz
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Feb 18
Very excited about this study in @EmboMolMed, where we show that KRAS mutations drive glycolytic reprogramming of the endothelium in sporadic brain arteriovenous malformations. We show a synergistic impact of targeting glycolysis and MEK. link.springer.com/article/10…
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Feb 18
Work was led by Ruilin Wu with collaboration with Negar Khosraviani, Ann Mansur, Kathryn Howe, Ivan Radovanovic, Josh Wythe and many others. @UHN
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Jason Fish retweeted
Jan 31
Thank you @kat_howe and @FishLab_UHN !! It was an absolute pleasure completing this journey with your guidance and support. Very excited to share our research story in the days ahead!
Jan 30
A celebratory moment for Dr Steven Botts. Newly minted PhD! Congrats @SRBotts - you are an asset to every team you join. Our lab has been enriched by you. Looking forward to showcasing your exciting work!
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Jason Fish retweeted
Jan 20
#CTRCD may be identifiable before therapy begins. In #HER2 #breastCA pretreatment endothelial & inflammatory biomarkers: ANGPT2, MPO, & endoglin, outperformed clinical & CMR in predicting cardiac dysfunction jacc.org/doi/10.1016/j.jacca…
#JACCCardioOnc #BCsm @dineshpmcc1 @FishLab_UHN
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Jason Fish retweeted
18 Aug 2025
Yep 👇this is what it’s all about! Come work with us at howeandfishlabs.com @FishLab_UHN @kat_howe So many great endothelial centric stories. Keen on vascular biology? Cool cellular communication? Cell identity? Novel therapeutic strategies? 😎UHN Canada Leads filling fast!
19 Jun 2025
UHN's bold Canada Leads initiative aims to attract top US researchers amid funding cuts, creating a unique opportunity to recruit global talent. With a vision to elevate excellence, Toronto is set to be a leading hub for scientific innovation.
Read more: bit.ly/44h1hsS
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Jason Fish retweeted
19 Dec 2025
Exciting work by @FishLab_UHN using #cardioncology cohorts @PMunkCardiacCtr / combined blood biomarkers approach to predict #CTRCD @JACCJournals even before cancer therapy. Reach out if u have banked blood for additional external validation.@ICOSociety @CCardiacON @UHN @UofT
18 Dec 2025
Excited to share our paper jacc.org/doi/10.1016/j.jacca…. Together with @dineshpmcc1 and led by Dakota Gustafson and Priya Mistry, we show that elevated levels of inflammatory and endothelial activation biomarkers before treatment can predict cancer therapy-related cardiac dysfunction.
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18 Dec 2025
Excited to share our paper jacc.org/doi/10.1016/j.jacca…. Together with @dineshpmcc1 and led by Dakota Gustafson and Priya Mistry, we show that elevated levels of inflammatory and endothelial activation biomarkers before treatment can predict cancer therapy-related cardiac dysfunction.
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Jason Fish retweeted
27 Nov 2024
So excited to share the first paper from the lab!
We identified CD34 as a marker of the heart’s SAN pacemaker cells enabling their isolation from stem cell differentiation cultures, advancing future disease modeling and biological pacemaker applications.
nature.com/articles/s41467-0…
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Jason Fish retweeted
15 Nov 2024
We're back with another PA Day at UHN! We have two exciting sessions today with students from schools across the GTA coming in to explore #STEM. Stay tuned for some fun snapshots. 💡
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Jason Fish retweeted
14 Nov 2024
On #WorldDiabetesDay we celebrate the next generation of diabetes researchers - like Cori Lau from @FishLab_UHN. Cori shares why diabetes research matters to him. #WDD2024
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Jason Fish retweeted
7 Nov 2024
Our next Trainee Lab Seminar Series will take place in-person on Friday, Nov. 15 at 12 p.m. at the Toronto General Hospital. Members from Drs. @TonyKTLam, @FishLab_UHN and Laura Chiavaroli labs will present their latest research. Learn more & register. mailchi.mp/4a1ee55d61ad/bbdc…
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Jason Fish retweeted
5 Nov 2024
#exosomes from cardiomyocytes hurt and from endothelial cells aid vascularization
Endothelial extracellular vesicles enhance vascular self-assembly in engineered human cardiac tissues doi.org/10.1088/1758-5090/ad… via @Biofabrication
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Jason Fish retweeted
4 Nov 2024
Don’t miss our next CCON Webinar on Nov 8th at 12pm EST! We will hear from Drs. Dinesh Thavendiranathan (@dineshpmcc1) & Ian Paterson (@HeartInstitute) about the role of cardiac MRI in cardio-oncology 🫀🩺
Register here: tinyurl.com/yrvzmspy
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Jason Fish retweeted
17 Oct 2024
⛰️ #TestYourLimits is gearing up for another expedition...and it's a BIG one! In 2023, we reached new heights in Ecuador, overcoming obstacles & celebrating team wins. This Nov. we have something extra special in store. Can you guess where we're going? ➡️ youtube.com/watch?v=NpReQjxx…
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Jason Fish retweeted
14 Oct 2024
Our paper on endothelial - cardiomyocyte crosstalk in #LongCovid is now online @NatureCVR. It highlighting the importance of early vascular health monitoring in patients with #LongCovid. @iDilipThomas @StanfordCVI @StanfordSurgery @maryhawn @StanfordVasc
nature.com/articles/s44161-0…
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Jason Fish retweeted
10 Oct 2024
This AHA scientific statement discusses the pathogenic mechanisms that link three prevalent cardiac diseases of adults:
➡️Heart failure
➡️Atrial fibrillation
➡️Coronary heart disease
These are three disorders that can lead to cognitive impairment and poor brain health.
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8 Oct 2024
What a huge accomplishment! Congrats, Priya.
8 Oct 2024
Truly humbled and honoured to be awarded CIHR Vanier Scholarship! Feeling immensely grateful to all those who have guided and supported me in this journey and to be working on this important project in Dr. Jason Fish's lab! A huge thanks to everyone that supported my application!
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Jason Fish retweeted
27 Sep 2024
Congratulations to Dr. Jason Fish for winning the 2024 Mid-Career Excellence Award in Blood and Blood Vessel Research!
Dr. Fish’s background in gene regulation of blood vessels came together beautifully as he delivered his lecture entitled “Oncogenic signaling in the endothelium drives arteriovenous malformations” presented at the Canadian Lipid & Vascular Summit.
Thank you to the Canadian Society of Atherosclerosis, Thrombosis and Vascular Biology for their continued partnership with the Institute of Circulatory and Respiratory Health of the Canadian Institutes of Health Research @CIHR_IRSC.
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Jason Fish retweeted
Join us TOMORROW for a special seminar titled "Elucidating RNA processing mechanisms within nuclear compartments using RNA proximity labeling" with Laboratory Medicine and Pathobiology Tenure Stream Candidate, Nadiya Khyzha, PhD.
Friday, September 27, 11 am - 12 pm
MSB 4279
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