intensivist at Latin America Sepsis Institute a non-profit organization willing to improve Sepsis care in Brazil LA and LMICs Defending diversity in all fields
Editorial @FlaviaSepsis
Selection of the composite primary outcome
Interaction of shock (increased permeability)
Possible factors which may produce heterogeneity
#CCR23
Continuous administration of meropenem, compared with intermittent administration, does not improve clinically relevant outcomes in critically ill patients with #sepsis.
ja.ma/440XrSP#CCR23
the discussants/panelists @FlaviaSepsis and @JAMA_current reviewers/editors and editorialists have an overview and interpretation of findings that is likely better than that of we @GiacomoMonti authors!
read the editorial if you have few minutes
ja.ma/3qEaniY
8/
#CCR23 was wonderful! A unique chance to meet face by face and to discuss with the best trialists in the world! It was an honour to deliver the John Hinds lecture in the roadmap of BRICNEt! #bricnet
Trial stopped early for efficacy…. Results: *huge* benefit of VL v DL: successful intubation on first attempt 85.1% VL v 70.8% DL >>> absolute RR 14.3% P <0.001 !!! @PCCRG@CritCareReviews#CCR23 Incredible result 👉👉👉
We've just presented and published a multicenter RCT at #CCR23 and in @JAMA_current!
Continuous vs Intermittent Meropenem Administration in Critically Ill Patients with Sepsis: The #MERCYtrial!
🔗 jamanetwork.com/journals/jam…
This 🧵 will explain the study in detail /11
#FOAMcc
I think the real take home of #CCR23 is that @CritCareReviews is the best conference around. It’s just been hit after hit with the trials this year. I definitely need to plan to go in the future. So jealous.
@FlaviaSepsis more expensive and workload etc #CCR23
Depends… our nurses on regular ward and icu less work and happier with continuous #tazocin@radboudumc
Even less disposables necessary…
Catching the last lecture of #CCR23 while waiting for the train home. Excellent presentation from @FlaviaSepsis discussing research in Brazil. Nice to see we share the same challenges
Amanhã, a Profa. @FlaviaSepsis vai apresentar no maior congresso de trials de Medicina Intensiva (@CritCareReviews) sobre a BRICNET @bricnetbr, na John Hinds Lecture
1500 em Belfast / 1100 em Brasília
#CCR23
Incisive comments from @FlaviaSepsis who brings us back to earth 🌎 reminding us that in Latin Amer many OOHCA don’t reach hosp and so she only treats pts after in-hosp cardiac arrest 😞 we should be grateful for the advanced health systems! #CCR23@TAMEtrial@CritCareReviews