A human-AI collaboration to map the fly brain. Explore the connectome in Codex: codex.flywire.ai/

Joined August 2019
201 Photos and videos
Pinned Tweet
2 Oct 2024
Big news! The fly connectome is featured on the cover of a special edition of Nature. This is all possible thanks to the collaboration of 292 members of The FlyWire Consortium! nature.com/immersive/d42859-… Check out the thread for an overview of the 9 #flywire papers published today
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FlyWire retweeted
Just published yesterday, the #BANC! A full central nervous system (CNS) connectome of a limbed animal enables us to trace sensory-motor arcs and understand how the CNS controls the body. rdcu.be/fncjS #neuroscience @Nature, Video by @quorumetrix, sound on! 1/18
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Know students who love science, coding & data? Invite them to apply for the FlyWire virtual summer internship in connectomics: codex.flywire.ai/academy_sum…
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Congratulations @SebastianSeung @MurthyLab Gerald Rubin and John White on winning the Wiley Prize! Photos from today’s award lecture at @RockefellerUniv in Manhattan. princeton.edu/news/2026/02/1…
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Introducing Sponsored Neurons™. You can now promote your reconstructed neurons directly on FlyWire Codex through our new sponsorship platform. Highlight your best work, increase visibility, and reach more researchers across the community. Learn more: codex.flywire.ai/app/search
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FlyWire retweeted
We've uploaded a fruit fly. We took the @FlyWireNews connectome of the fruit fly brain, applied a simple neuron model (@Philip_Shiu Nature 2024) and used it to control a MuJoCo physics-simulated body, closing the loop from neural activation to action. A few things I want to say about what this means and where we're going at @eonsys. 🧵
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Codex dark mode 😎 Start yourself out with this view of the path from photoreceptors to a descending neuron (DNa01, involved in turning). What's your favorite 3D view? codex.flywire.ai/app/view_3d…
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FlyWire retweeted
Mala and I will be delighted to accept this award on behalf of the FlyWire Consortium of 75 laboratories and citizen scientists around the world!
Congratulations to FlyWire founders @SebastianSeung and @MurthyLab, who alongside John White and Gerald Rubin have been recognized with the Wiley Prize for their work pioneering connectome reconstruction & interpretation!
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Congratulations to FlyWire founders @SebastianSeung and @MurthyLab, who alongside John White and Gerald Rubin have been recognized with the Wiley Prize for their work pioneering connectome reconstruction & interpretation!
The Wiley Foundation is pleased to announce the winners of the 24th annual Wiley Prize in Biomedical Sciences, which recognizes contributions that open new fields of research or advance concepts in a particular biomedical discipline. John White, Gerald Rubin, Sebastian Seung, and Mala Murthy will be awarded for reconstructing and interpreting connectomes, the anatomical wiring diagrams of neurons and synapses that underlie how the brain processes information and controls actions. Learn more about the winners in our latest press release: ow.ly/qzgT50YhCAP
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The Institute for Advanced Study (@the_IAS), the fabled home of Einstein and Gödel, announces a 2026-27 program on Modeling Fly Vision, intended to refound theor/comp neuro on the bedrock of 21st century brain maps. Apply for membership! ias.edu/sns/csb#special-year
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FlyWire retweeted
Our Method of the Year 2025 is...drumroll please...EM-based connectomics!! Our Editorial introduces our choice and highlights six Comments and other related content in this special issue. Please join us in celebrating EM-based connectomics! 🎉🧠🔬 nature.com/articles/s41592-0…
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Method of the Year 2025: A Comment from @MurthyLab showcases how complete connectomes can yield hypotheses about circuit function and generate predictions that can be tested with genetic tools, as illustrated with examples from the Drosophila community. nature.com/articles/s41592-0…
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Method of the Year 2025: A Comment from @martamcosta2 discusses challenges and prospects of comparative connectomics, which provides insights into variability between individuals, changes during development, differences between sexes and evolutionary changes between species.
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Method of the Year 2025: In his Comment, @janfunkey discusses current challenges in connectomics, which is time-consuming and labor-intensive. He focuses on proofreading and discusses how automated models might be further developed to embrace uncertainty. nature.com/articles/s41592-0…
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Method of the Year 2025: In their Comment, Wei-Chung Allen Lee @darbly and Ramin Khajeh discuss alternatives to the well-established approaches used in connectomics. nature.com/articles/s41592-0…
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31 Oct 2025
Just a little neuron witch casting synaptic spells. Wishing you a Happy Halloween! flywire.ai
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27 Oct 2025
Level up your Codex query powers ✨ FlyWire Codex Workshop: Tomorrow! Tues Oct 28 @ 12:30 ET with @MatsliahArie and @amyneurons RSVP for Zoom info: docs.google.com/forms/d/e/1F… Recorded for FlyWire YouTube 📷 youtube.com/@flywireprinceto…
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24 Oct 2025
Today is the last day to sign up for Brain Simulation School! sjcabs.com/
What's better than talking about simulating brains? Actually doing it. Apply to the San Juan Winter School on Connectomics and Brain Simulation sjcabs.com/ Deadline extended to Oct 24!
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22 Oct 2025
Just over one year ago, the FlyWire Connectome was published in @Nature nature.com/collections/hgcfa… How has the connectome shaped your research? @FrankieRivera25 explores its impact in @_TheTransmitter's feature, interviewing nine researchers one year on: thetransmitter.org/the-big-p…
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21 Oct 2025
Looking to level up your FlyWire Codex skills? Join us for a Codex workshop on Tuesday October 28. Learn how to navigate, query, and visualize data. Suitable for new and experienced users. RSVP: forms.gle/rSmDmVpDeG1kvY7h8
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