Being an editor sometimes really tests your patience, especially when authors treat peer-review feedback and formatting as optional. We're not gatekeepers but your safety net. Revisions help your research survive scrutiny and earn citations. #PeerReview #JournalEditor #Science

Leaving the lab for leadership is a tough shift for scientists. We’re trained in data, but people management requires a completely different operating system. Engagement metrics reveal issues, but learning to structure teams effectively closes the gap. #Leadership #Science

📢We are looking for a motivated reseacher to join our in vitro gametogenesis program. If you are interested in germ cell biology, click on the link for more details: jobs.nottingham.ac.uk/vacanc… #stem #gametogenesis #notinthegenes

Exam season is here. Good luck to everyone! We, as teachers and examiners, do our best to help, but every so often things still don't go as planned... #ExamSeason #GoodLuck

Can cycloheximide cause DNA damage? Possibly. Inhibiting protein synthesis stresses cells and raises DNA‑damage markers like γH2AX — but are these actual DNA breaks or is it just induction of markers? #CellBiology #DNA

When you can't replicate published results, self-doubt sets in: why isn't it working? What´s wrong? In desperation, you start optimizing with what you have. Glad we did! We learned a lot, and now we´re looking forward to the key experiment. Exciting! #CellBiology #OocyteResearch

How do oocytes handle DNA damage when transcription is shut down? What I thought would be a small, fun project has ballooned into a nightmare of endless variables. Science really isn’t all sunshine and rainbows. #CellBiology #ReproductiveBiology #futureART

Bovine oocytes and embryos closely mirror human ones and are vital to reproductive research, yet they are notoriously challenging to handle. Many thanks to our colleagues in the Department of Reproduction at the Institute of Animal Science. #ReproductiveScience #AnimalScience

We are thrilled to be part of the ART FOR THE FUTURE project, aiming to explore new frontiers, from AI and germ cells in vitro to ethical or legal issues, bridging basic science and clinical practice. More: buff.ly/jF24A2d #futureART #Strategie_AV21 #ReproductiveMedicine

Check out these beauties! Our advanced-maternal-age oocyte media has produced its first embryos. It's both exciting and nerve-wracking, but I love every moment! 🤩 #Embryology #Innovation

How can we tackle issues like DNA damage or mitochondrial dysfunction in embryos? By intervening before the first embryonic replication, we can prevent these issues from becoming permanent, ensuring healthy development. Read more: buff.ly/gPwRBk1 #Genetics #Embryology

Curious about why some genes are favored in the egg during meiosis or how selfish genetic elements break Mendel's rules? Join us on April 2nd at the Institute of Experimental Medicine to learn more! #Genetics #Meiosis #ScienceEvent

Ever wondered about the function of nucleoli in zygotes and early embryos, and their interaction with the embryonic genome? Mark your calendars! #Embryology #Genomics

It took me a while to realize that signs of oocyte aging aren't uniform (why would they be, right?): Two mouse strains, similar in age, completely different spindle traits. How much does this apply to human individuals? #OocyteAging #GeneticDiversity

After sharing the advanced publication access few weeks ago, I am now pleased to share the final typeset version, open access, of my group’s latest contribution in Molecular Human Reproduction doi.org/10.1093/molehr/gaag0… In a nutshell, we report that the first two blastomeres are reciprocally different in terms of epiblast production, for reasons that seem to depend on the site where the spermatozoon penetrated the oocyte, in mice. Our half-cell proteomics data supports that this difference is possibly due to heterogeneities in ooplasm composition and how they are apportioned into the blastomeres depending on the orientation of the first zygotic division. Thanks to the co-Authors, to the Reviewers, to the Journal, and I hope you like the paper!

How does one identify an oocyte with good developmental potential? Contrary to the often-reported decrease in maturation rate with advancing age, we never observed any difference. Has anyone truly witnessed this, or is it just the result of pressure to meet expectations/publish?

Our first attempt with media tailored for oocytes from older females shows promising results: significantly reduced DNA damage and a 50% increase in the number of euploid oocytes! But will this work for boosting blastocyst formation rates as well? 🤔

Happy Sunday! Don't miss the latest issue of #cebooc featuring the newst papers on oocyte and embryo biology! biomed.news/bims-cebooc/2026… Highlight: pubmed.ncbi.nlm.nih.gov/4172… Thanks @Bims_BiomedNews for preselecting!

Is the role of the spindle and non-chromosomal egg elements in aneuploidy underestimated? Research shows that placing young germinal vesicles (Y GVs) into the cytoplasm of aged (AMA) oocytes increases aneuploidy rates. For more details, see: onlinelibrary.wiley.com/doi/…

Tracking the movement of nucleoli in parental pronuclei could be instrumental in selecting top-quality human embryos. This movement could potentially be driven by nuclear actin, which facilitates the motion of the nucleoli: academic.oup.com/reproductio…