We study chromatin conformation regulating transcriptional dynamics in mature cells

Joined January 2019
23 Photos and videos
Furlan-Magaril_lab retweeted
We just finished writing up this beautiful story on how transcription factors can generate pulses by using chromatin (led by Cece & @ECosta173 ): Bifunctional transcriptional effector domains control gene expression pulses in an occupancy-dependent manner biorxiv.org/content/10.64898…
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Fue un éxito!!! Muchas gracias a todos los ponentes y participantes que nos acompañaron. 🤗🤗🤗
Ayer en el instituto se llevó a cabo el Minisimposio por 25 años de Epigenética en México, un evento que reunió a ponentes nacionales e internacionales investigando diferentes rubros de la epigenética en distintos modelos. ¡Gracias por asistir!
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No se lo pierdan!!! Minisimposio de epigenética en México. Un lineup increíble de ponentes!!! 18 y 19 de Noviembre en el IFC les esperamos (registro en el QR anexo).
🗓⏰📍Minisiposio por 25 años de Epigenética en México, martes 18 y miércoles 19 de noviembre de 9:30 a 17:00 hrs., auditorio Antonio Peña. Responde este formulario para acudir: forms.gle/VJnQRF9NKQxjLvye9 Algunas charlas se van a transmitir por YouTube: youtube.com/@institutodefisi…
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Furlan-Magaril_lab retweeted
Liveposting on Bluesky: Lingbin Ni: Haplotype-resolved chromatin differences and genome structural variation #ASHG25 bsky.app/profile/michaelhoff…

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And it’s out! Thanks you @NatureSMB for the kind invitation! Come have a read 😊 “Returning home: a story of chromatin and community” rdcu.be/eJGcQ

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Furlan-Magaril_lab retweeted
Replying to @arjunrajlab
There is a lot of truth to this. The advances in sequencing throughput continue. The one exception might be 3D genomics. 100x coverage of the human 3D genome at nucleosome resolution would require 10^16-17 reads: nature.com/articles/s41588-0…

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Furlan-Magaril_lab retweeted
Estimados colegas y miembros de la Sociedad Mexicana de Inmunología, les compartimos la propuesta de candidatura que el Dr José Luis Maravillas JL Maravillas Montero y yo estamos sometiendo para ocupar los puestos de vicepresidente y prosecretario de la SMI, voten por nosotros
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Furlan-Magaril_lab retweeted
Our new preprint is out! We combined single-nucleosome imaging and 3D-SIM to reveal: 🔹 Euchromatin forms condensed domains, not open fibers 🔹Cohesin loss increases nucleosome mobility without decompaction 🔹Cohesin prevents neighboring domain mixing Full story & movies👇
Is euchromatin really “open”? 🧬Our new study @bioRxiv suggests otherwise. Using super-resolution imaging🔬 @shiori_iida @MasaAShimazoe reveals: Euchromatin forms condensed domains in live cells. Cohesin constrains them and prevents domain mixing. 🔗biorxiv.org/cgi/content/shor… (1/3)
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Furlan-Magaril_lab retweeted
Think babies are born without a body clock? ⏰ Not true! By the time they’re born, infants already have a working circadian system that responds to light. Here’s the timeline of how their internal clock develops before birth 👇@LauraKervezee frontiersin.org/journals/neu…
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Furlan-Magaril_lab retweeted
🚨New preprint from the lab🚨 🧬 What keeps certain chromatin domains anchored at the nuclear periphery? Our new genome-wide HiDRO screen uncovers a key role for RNA-binding protein hnRNPK. biorxiv.org/content/10.1101/…
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Furlan-Magaril_lab retweeted
WORK! My lab currently have 5 (!) open positions for postdocs/PhD students for: -Nanopore protein sequencing -Archaeal CDV cell division -Microfluidics for synthetic cells -Nuclear Pore Complex -Origami mimics of peroxisomes Please apply! ceesdekkerlab.nl/come-join-u… RT=👍
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Furlan-Magaril_lab retweeted
SCIENCE IN MEXICO: A RISING FORCE AMID ADVERSITY. I came back knowing the funding would be scarce, the bureaucracy maddening, and the equipment overpriced. But also knowing I’d find freedom, brilliant students, and generous colleagues. I have no regrets shorturl.at/Mqd1N
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Very happy this is out. Come and have a read :)) It was a pleasure to write this with @Valdes_Lab_ Science in Mexico: a rising force amid adversity sciencedirect.com/science/ar…

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We wrote this review a while back but somehow I do not see it in pubmed... so here it is again "Distal and proximal control of rhythmic gene transcription" 😀🌕🌓🌑🕛🕒🕕🕘🕛🌍 frontiersin.org/journals/sys…
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Furlan-Magaril_lab retweeted
It's out! Our Science & Society article in @TrendsCellBio , in collaboration with @rocamboleando Unlocking Latin America´s scientific potential: challenges and opportunities in a globalized world 🌎 cell.com/trends/cell-biology…

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