Back traveling again (!!!) ...
Joined January 2011
- Tweets 186
- Following 444
- Followers 266
- Likes 239
21 Photos and videos
Michael Keogh retweeted
Feb 18
Now streaming ▶️
Missed Michael-Christopher Keogh’s talk in the 2026 Fragile Nucleosome series? The replay is live on YouTube.
🔗 Watch now: youtu.be/JxlLsmAa2jo
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Jan 16
Some forms of heterologous competition for the nucleosome acidic patch are tolerated by cells, but an 'arginine anchor' causes profound problems. A collaboration between labs of Jim Kadonaga, @valendraica, @GCloner, @EpiCypher and @ujanichakrabort in @jesstylerlab.
A wonderful collaboration between @jesstylerlab, @epicypher, @gcloner, James Kadonaga and our lab at PSU. In this article, we provide the significance of the nucleosome acidic patch
doi.org/10.64898/2026.01.14.…
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Michael Keogh retweeted
5 Nov 2025
Our #Epi2025 Trainee Session honoring the legacy of C. David Allis was an incredible success last night! Huge thank you to our selected trainees for sharing their outstanding research, and to our session chairs for organizing such a thoughtful introduction honoring Dave.
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Michael Keogh retweeted
2 Oct 2025
Today, we introduce a nomenclature that can express discrete PTMs, proteoforms, nucleoforms, or situations where defined PTMs exist in an uncertain context and can describe how proteoforms are configured in functionally distinct complexes across biology. authors.elsevier.com/c/1lt5I…
ALT Today, we introduce a nomenclature that can express discrete PTMs, proteoforms, nucleoforms, or situations where defined PTMs exist in an uncertain context. Though specifically designed for the chromatin field, adaptions of the framework could be used to describe—and thus dissect—how proteoforms are configured in functionally distinct complexes across biology. Thank you to the many co-authors for your input and support. https://authors.elsevier.com/c/1lt5I3vVUPVb4c
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30 Apr 2025
22x Chromatin Readers dissected for their histone nucleosome binding by biochemical, proteomic and genomic approaches - major biological insight revealed [!] ..[biorxiv.org/content/10.1101/…] @epicypher @MusselmanLab @NLKProteomics
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25 Jun 2024
Chania Crete for Aegean Conference ! Going to guess the local Mouse population is minuscule and edgy ..
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Michael Keogh retweeted
29 May 2024
To begin to undercover immune cell diversity, we partnered with @ImmGen_ to use our low-input automated CUT&RUN platform to process >1,100 samples and generate chromatin profiles from 94 cell types, including ultra-rare cell populations.
Explore here! hubs.la/Q02yR7Fr0
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29 May 2024
Welcome to Busan Korea .. the location for KSBMB .. and apparently that breeding colony you’re having problems with (presumably the kimchee is key) …
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28 May 2024
They have a beautiful campus at Seoul National University - as I found out when I gave the wrong address to Taxi driver - a very pleasant 30min walk ensued to visit Sung Hee Baek ! #asiatravels
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28 May 2024
Behold : the coin-on-side stability of the Shanghai to Beijing bullet train [and at 347kph / 215mph] !
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Michael Keogh retweeted
4 Apr 2024
Another great day at EpiCypher! We hosted @NLKProteomics - who described how mass spectrometry methods are transforming the study of nucleosome modifications and the histone code.
Great to see you, Neil!
ALT Dr. Neil Kelleher presenting on the Human Proteoform Project: Defining the human proteome
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Michael Keogh retweeted
7 Mar 2024
A lot of fun to highlight great work from @GiuseppeLeuzzi_ and @CicciaAlberto et al showing how the the DNA translocase SMARCAL1 dampens immune responses against tumor cells through two distinct mechanisms. Together with @Ele_Toufektchan in @MolecularCell. authors.elsevier.com/a/1ijJ1…
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Michael Keogh retweeted
6 Mar 2024
Publication alert ! Paper from helmholtz-munich.de/en/ife in @Nature
How complex epigenetic modification signatures regulate genome function. With interactive online resource marcs.helmholtz-munich.de/ Big data ! @epigeneticsHMGU @HelmholtzMunich
nature.com/articles/s41586-0…
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Michael Keogh retweeted
6 Mar 2024
“If you want to know someone, look at their friends…” that’s how we decode histone codes and chromatin states.
Finally, the dream has come true… Almost a decade after I started the project in London, it has been published on Nature.
Enjoy the paper: nature.com/articles/s41586-0…
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6 Mar 2024
Some of what we've been up to for the past while ...
26 Feb 2024
Don't miss out! On March 14th at 12PM EST EpiCypher CSO @GCloner will present, 'Next generation epigenetic insight with fully-defined nucleosomes.' Register today: hubs.la/Q02lXzHb0
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Michael Keogh retweeted
29 Feb 2024
I was deeply honored to be recognized during the @GatorsMBK game tonight! Achieving @UFHealthCancer designation from @theNCI was a team effort involving the tremendous efforts of researchers and staff across @UF and the support of our community, state & federal partners.
ALT Dr. Licht gives a high-five while being recognized on court at the Gators men's basketball game.
ALT Dr. Licht is recognized on court at the Florida Gators men's basketball game.
ALT Dr. Licht is recognized on court at the Florida Gators men's basketball game.
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27 Feb 2024
What is the state of possible for extracting open chromatin data from banked clinical samples - specifically FFPE patient tissues ? We've been thinking about it (helps when you're planning to do it) : our field review. @epicypher @NEBiolabs #chromatin preprints.org/manuscript/202…
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26 Feb 2024
Product of a collaborative project with the newly minted Dr. Chad Hicks PhD (huge congratulations to same !) : H2BK120 controls access to a hub of nucleosome engagement : the acidic patch. @CWolberger @HicksChadW @epicypher #nucleosome biorxiv.org/content/10.1101/…
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Michael Keogh retweeted
25 Feb 2024
"A true mentor is someone who has more imagination about you than you have about yourself"
nejm.org/doi/10.1056/NEJMp23…
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