GPnotebook helps busy GPs save time by providing easy access to reliable, concise information to support quicker, more assured clinical decision-making.

Joined March 2012
338 Photos and videos
Did you know? Lecanemab and donanemab are amyloid-targeting immunotherapies that are approved in the UK for mild cognitive impairment or mild dementia in Alzheimer's disease, with the exclusion of homozygote carriers of the 4-allele of the apolipoprotein E gene. See link ⬇️.
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A recent MHRA drug safety update warns that overuse of nasal decongestant sprays and drops containing xylometazoline hydrochloride or oxymetazoline hydrochloride carries an increased risk of rebound congestion, rhinitis medicamentosa and tachyphylaxis. See link ⬇️.
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In this week's episode of GPnotebook TV, Dr @LisaDevineGP discusses a study that explored primary healthcare professionals' perspectives on the barriers and facilitators to support self-management in people living with multiple long-term conditions and socioeconomic challenges.
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In this week's GPnotebook Podcast episode, Dr Hannah Rosa discusses bacterial meningitis and meningococcal disease, with a focus on the NICE guideline that was published in 2024. Episode link below ⬇️.
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In a study of adults with acute hyperkalaemia, achievement of potassium normalisation was similar for both sodium polystyrene sulfonate and sodium zirconium cyclosilicate treatments, with normalisation occurring faster with sodium zirconium cyclosilicate. See link ⬇️.
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With respect to antibiotic prophylaxis in infants with Grade III, IV or V vesico-ureteric reflux, a study found that continuous antibiotic prophylaxis for 2 years reduced the occurrence of a first urinary tract infection versus no treatment. See link in comments ⬇️.
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Did you know? Limb girdle dystrophy refers to a broad heterogeneous group of genetic disorders characterised by postnatal onset and progressive weakness. Mostly, the weakness is predominantly symmetric, typically affecting the pelvic or shoulder girdle musculature. See link ⬇️.
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In this week's episode of GPnotebook TV, Dr @LisaDevineGP discusses an article evaluating the benefits of combined high-intensity circuit training plus a sleep health intervention, versus either intervention alone, in women with a sedentary lifestyle and poor sleep health.
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In this week's GPnotebook Podcast episode, @rogerthedoctor explores anabolic–androgenic steroid misuse, covering its appearance-driven causes, pathophysiological risks and clinical strategies for GP identification and withdrawal management. Episode link below ⬇️.
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Did you know? Rectus abdominis diastasis (RAD) is characterised by the pathological separation of the two rectus abdominis muscles along the linea alba. A study showed that structured exercise programmes significantly reduce inter-rectus distance in women with RAD. See link ⬇️.
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