@GeiselBiofilm profile picture
George O'Toole (he/him/his) @GeiselBiofilm

Editor in Chief, Journal of Bacteriology; Bacterial Biofilms, Surface Sensing, c-di-GMP Signaling, Polymicrobial Communities & Gut Microbiota in Cystic Fibrosis

Joined June 2017
  • Tweets 1,866
  • Following 6
  • Followers 6,485
581 Photos and videos
I'm out! Thanks for all those who have followed posts on JB and our lab research. Please find me at BlueSky @geiselbiofilm.bsky.social
2
1
640
New in JB: Roberge & Burrows review the role of the PilB ATPase and other factors in the assembly of type IV pili. journals.asm.org/doi/10.1128… @ASMicrobiology @JBacteriology
2
16
1,328
I am looking for a research associate - a recent college grad with BS or equivalent. Apply online! searchjobs.dartmouth.edu/pos…

3
14
22
3,398
Working on biofilms!
1
1
519
George O'Toole (he/him/his) retweeted
ASM
@ASMicrobiology
28 Jan 2025
TfpY is a conserved accessory protein found in type IV pili (T4P)-expressing bacteria. While T4P are often phage receptors, research in #JBacteriology suggests TfpY does not mediate phage defense, but instead facilitates efficient pilus assembly/function. asm.social/2gA
TfpY expression promotes type IV pilus assembly and function. (A) Type IV pilin operon in P. aeruginosa PA14.

ALT TfpY expression promotes type IV pilus assembly and function. (A) Type IV pilin operon in P. aeruginosa PA14.

1
5
14
2,836
New in JB: Romanov and O'Connor will teach you about the history of Legionella, and its tremendous role as a tool to understand host biology. pubmed.ncbi.nlm.nih.gov/3963… @ASMicrobiology @JBacteriology
3
13
1,024
Pls share: Tenure-Track Assistant Professor of Microbiology, Hofstra University, NY Full ad and application link: hofstra.peopleadmin.com/post…
40
40
5,716
My last week on X. Please find me at @GeiselBiofilm on BlueSky
287
New in JB: Garretto, Woods et al. examine 2,248 clinical E. faecium isolates and show that Bacteriocin 43 (bac43) is highly conserved and increasing in prevalence, which has implications for infections/spread by this pathogen. @asm.org #Jbacteriology journals.asm.org/doi/10.1128…
1
3
652
George O'Toole (he/him/his) retweeted
ASM
@ASMicrobiology
23 Jan 2025
Know an outstanding lecturer? Nominate them for the ASM Distinguished Lecturer (ASMDL) roster, a group of accomplished scientists who deliver lectures & participate in career development & mentoring activities at ASM Branch meetings. Submit by Jan. 28! asm.social/2g5
Audience at a lecture.

ALT Audience at a lecture.
2
2
1,577
George O'Toole (he/him/his) retweeted
Dartmouth CF Research Center@DartCF
23 Jan 2025
Join us!
1
1
4
358
New in JB: Brezovská, Krásný et al. show that a σA-MoaB2 interaction modulates gene expression in. M smegmatis - and they solve the structure of MoaB2, too. journals.asm.org/doi/10.1128… @ASMicrobiology @JBacteriology
1
402
Pls share: Penn State Berks, a college of Penn State University in suburban Reading, has a Tenure-track appointment in biology with a focus in prokaryotic microbiology starting August 2025. A Ph.D. in microbiology or a related field is required. berks.psu.edu/

Penn State Berks

berks.psu.edu
22
28
3,666
2 weeks til my X-it. If you are interested in biofilms and ASM publishing, please join me on Blue Sky: @geiselbiofilm.bsky.social
3
323
A new direction for research in the lab around carbon sequestration! irving.dartmouth.edu/news/20…

Two Professors Receive $100,000 Pilot Grant to Enhance Understanding

Two Dartmouth faculty members have been awarded a $100,000 pilot grant to deepen our understanding of the role of marine microbes in carbon sequestration.

irving.dartmouth.edu
5
3
23
2,022
JB Editor's Choice: Ramírez-Guadiana, Rudner et al. perform a genetic screen to identify spore germination genes. Their data support a model whereby GerY, GerT, and the GerP play a role in the transit of nutrients across the spore coat. journals.asm.org/doi/10.1128… @ASMicrobiology
2
10
978
George O'Toole (he/him/his) retweeted
ASM
@ASMicrobiology
17 Jan 2025
Mycobacterium abscessus (Mabs) is often found in the cystic fibrosis (CF) lung, where it forms biofilms. Exogenous heme alters Mabs biofilms by preventing formation of a submerged film and promoting the growth of unattached aggregates. @JournalSpectrum: asm.social/2fM
Effects of shaking and standing growth on intracellular heme and extracellular porphyrin in mycobacteria. (A) Intracellular heme arbitrary fluorescence units/optical density (AFU/OD) normalized to shaking in Mabs in standing conditions (stand) vs shaking (shake) at 37°C in Sauton’s media. (B) Extracellular porphyrin fluorescence (AFU 654 nm) normalized to OD in Mabs in standing conditions vs shaki

ALT Effects of shaking and standing growth on intracellular heme and extracellular porphyrin in mycobacteria. (A) Intracellular heme arbitrary fluorescence units/optical density (AFU/OD) normalized to shaking in Mabs in standing conditions (stand) vs shaking (shake) at 37°C in Sauton’s media. (B) Extracellular porphyrin fluorescence (AFU 654 nm) normalized to OD in Mabs in standing conditions vs shaki
8
34
2,845
Just published a new paper with our collaborator here at Dartmouth - Mukul Sharma. This project leverages disciplines from micro to earth sciences to oceanography to explore a new mechanism of carbon sequestration. nature.com/articles/s41598-0…
3
14
1,132
JB Editor's Choice: Carey, Parsek et al. explore the regulation of the Psl matrix component by QS. journals.asm.org/doi/abs/10.… @ASMicrobiology @JBacteriology
3
8
715
Hi all: I will be X-iting this feed soon and moving to BlueSky: Find me at @geiselbiofilm for all things JB, ASM journals and O'Toole lab and Dartmouth microbiology related posts. I'll keep you posted.
1
363
Load more