📢 What is the relationship between polygenic risk and individual symptoms of psychopathology? In a new pre-print (and my first PhD study!) we combine network analysis and polygenic risk scores ⬇️ psyarxiv.com/6mzxd/ [1/9]
Just out in @NatureHumBehav
👇🏼👇🏼
We focused on the causes & impact of self-report error in the UK Biobank. We found that reporting error does not occur at random, is not independent of other participation behaviours, and can complicate the interpretation of genome-wide findings
New preprint is out @medrxivpreprint 👇
Here, we assess the impact of error in self-report measures in the UK Biobank: what are the implications for (genetic) epidemiology?
medrxiv.org/content/10.1101/…
(1/) 🧵🧵
Excellent blog by @GiuliaPiazza15 & @jonroiser for @mental_elf on our paper on depressive symptom dynamics and the need to improve clinical characterisation of mental disorders by taking into account their dynamic nature & the disorder evolution over time
nationalelfservice.net/menta…
enjoyed writing this blog with @GiuliaPiazza15 on a recent study describing individal symptom networks in depression @AndreaCipriani@OmidVEbrahimi. Will be interesting to see how this develops and whether network structure is associated with response to interventions!
In a 3 cohort and 3 measure replication (ALSPAC @CO90s, #ABCDstudy, MCS @CLScohorts) we found:
1. Network temperature 'cooling' across adolescence indicating ⬆️ network stability and ⬇️ symptom variability (more alignment) with age ❄️
[5/9]
🚨🌡️New pre-print on PsyArXiv!
We conceptualise and investigate network temperature as a measure of longitudinal stability in depression symptom networks across adolescence...
osf.io/preprints/psyarxiv/9z… [1/9]
Pre-doc RA job in our NMH lab at @UCL_ICN with @olijrobinson! Focusing on mechanisms of treatment in anxiety, a great opportunity to learn skills in mental health/neuroscience/computational research and work in a collaborative environment, deadline Aug 7th ucl.ac.uk/work-at-ucl/search…
Which specific mental health symptoms are associated with genetic risk? Answers in our new Jama Psychiatry paper led by @GiuliaPiazza15 in n=5521 with preregistered replication in n=4625.
jamanetwork.com/journals/jam…
JOB ALERT: We're advertising for a ~1-year Research Assistant on the @The_MRC funded ReThink project. @UCLPALS
Ideal for those interested in child trauma, mental health and wellbeing. Qualitative or mixed-methods experience ideal.
Link below:
jobs.ac.uk/job/DID695/resear…
Combining networks and polygenic scores, this study shows polygenic scores for psychopathology traits associate with a restricted number of trait-relevant and cross-trait symptoms, replicated in an independent sample with preregistered analyses. ja.ma/3z1dwOc
📢 Our paper (my first PhD study!) on the association between bullying victimisation and adolescent mental health across national contexts is now published in the journal of European Child & Adolescent Psychiatry 🧵 [1/5]
🔗 link.springer.com/article/10…
Just concluded our 2024 UCL-Wellcome Mental Health Science PhD Retreat with all four cohorts!
Huge gratitude to @wellcometrust & @ucl for their unwavering support throughout our PhD journeys! 🧠
📣Exciting RA position with @docqhuys and our wonderful Applied Computational Psychiatry lab @UCLPsychiatry @MPC_CompPsych!📣
Work on a longitudinal study examining the processes engaged by psychotherapy in the NHS:
ucl.ac.uk/work-at-ucl/search…
Apply and share!
We have a new preprint out! Intergenerational transmission of polygenic predisposition for neuropsychiatric traits on emotional and behavioural difficulties in childhood
osf.io/preprints/psyarxiv/w4…
We are now recruiting for the fifth (and sadly, final) cohort of the UCL-Wellcome 4-year PhD in Mental Health Science, closing date 10th January. For more info, including videos of our online "Roadshows", see our "How to apply" page ucl.ac.uk/mental-health/stud…
Massively excited to finally be able to share this amazing news! @wellcometrust have awarded UCL a 4-year PhD programme in Mental Health Science. Looking forward to working with @DrAPitman, @annaremington, @PascoFearon, Claudia Cooper and Marcus Richards bit.ly/2maUcbz